People: Cancer Biology
Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
Research in my lab focuses on the role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. We are also interested in signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.
Associate Professor of Biomedical Engineering
The Hayes lab group focuses on biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. The research efforts in these areas are materials centered with an emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts in the lab include the development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.
Professor, Veterinary & Biomedical Sciences; Director, Animal Resource Program
The pathogenesis of infectious disease: examining bacterial virulence and associated pathology in relation to host immune responses.
Associate Professor of Food Science
Dietary polyphenols in prevention of obesity and fatty liver disease; efficacy and mechanisms of action of food-derived phytochemicals in prevention of lung cancer; biotransformation, bioavailability and potential hepatotoxicity of dietary phytochemicals
Assistant Professor of Biomedical Engineering
The Medina Group focuses on the design of bio-inspired functional materials that serve as new tools in precision medicine. Central to our work is understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. Mechanistic insights gained from these studies guide the design of nano- and micro-scale biomaterials around which we develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer.
Professor of Veterinary and Biomedical Sciences; Emphasis Area Representative, Genetics
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress
Distinguished Professor of Molecular Toxicology and Carcinogenesis
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.
Professor of Immunology and Molecular Toxicology
Molecular mechanisms by which bioactives such as selenium, omega-3 fatty acids, and other products of natural origin alter the host response and immune function in inflammation and cancer
Director, Huck Institutes of the Life Sciences; Evan Pugh Professor of Biology and Entomology; Eberly Professor of Biotechnology
The ecology and evolutionary genetics of infectious disease.
Associate Director, Huck Institutes of the Life Sciences; Associate Professor; Broadhurst Career Development Professor for the Study of Health Promotion and Disease Prevention
Role of changes in energy balance and related nutritional factors on inflammation, immune regulation and cancer risk using both animal models and human subjects.
Associate Professor of Biochemistry and Molecular Biology
Epithelial cells form barriers that divide different compartments in the body. These cells are normally stationary but become migratory during processes such as the repair of tissue damage or the metastasis of epithelial tumors. The Santy lab is interested in understanding the signals and processes that initiate migration in epithelial cells.
Assistant Professor of Biobehavioral Health
Interdisciplinary approach to identify mechanisms underpinning the biological embedding of stress across the lifespan with a special focus on biological aging.
Associate Professor of Chemistry; Associate Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.
Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.
Associate Professor of Bioengineering
My laboratory aims at developing and applying micro/nano technologies for biological and medical applications. On one hand, I am interested in studying miniaturized devices and systems that can be integrated with biological system in vitro and in vivo. On the other hand, I am eager to apply these technologies for fundamental biological research, clinic diagnosis and treatment. The research is highly multidisciplinary, interfacing at engineering, biological sciences, physical sciences, and medicine.