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Biomolecular Interactions Facility

Analyzing the binding and folding of biological macromolecules using high-throughput thermodynamic calorimetry instruments

The Biomolecular Interactions Core Facility provides the necessary infrastructure and support for individual investigators to undertake studies of macromolecule binding and folding, as well as protein and lipid quantification. Our calorimetry instruments are fully automated and require the least amount of sample of any commercially available instruments. Specifically, we provide instrumentation and collaborative assistance for:

  • Isothermal titration calorimetry (ITC)for studying ligand-macromolecule binding
  • Differential scanning calorimetry (DSC)for investigating stability and folding thermodynamics

Our experienced staff is available to assist with project development and research.

Research

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News

Craig Praul named director of Huck Core Facilities

Joining Praul on the new leadership team are Rajeswaran Mani, director of the Flow Cytometry Facility, and financial specialist Kelly Foster.

Undergraduate research may contribute to COVID-19 treatments

Brandywine undergraduates worked with professor to investigate potential new therapies to inhibit an enzyme that helps the coronavirus replicate

Core facilities director brings more than technical advice to research

Directors of the core facilities at Penn State’s Huck Institutes of the Life Sciences are more than expert technicians — they are also researchers in their own right. And though their unique contributions are not always consistently recognized within the broader community, faculty researchers who work in the core facilities are well aware of these unsung heroes' many impressive insights.

News

Craig Praul named director of Huck Core Facilities

Joining Praul on the new leadership team are Rajeswaran Mani, director of the Flow Cytometry Facility, and financial specialist Kelly Foster.

Undergraduate research may contribute to COVID-19 treatments

Brandywine undergraduates worked with professor to investigate potential new therapies to inhibit an enzyme that helps the coronavirus replicate

Core facilities director brings more than technical advice to research

Directors of the core facilities at Penn State’s Huck Institutes of the Life Sciences are more than expert technicians — they are also researchers in their own right. And though their unique contributions are not always consistently recognized within the broader community, faculty researchers who work in the core facilities are well aware of these unsung heroes' many impressive insights.

Partnership announced between Commonwealth Campuses and shared facilities

The Office of the Vice President for Research at Penn State has announced the launch of a new program to support increased usage of shared core facilities and services by faculty at the Commonwealth Campuses.