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Automated Calorimetry Facility

Analyzing the binding and folding of biological macromolecules using high-throughput thermodynamic calorimetry instruments

The Automated Biological Calorimetry Facility provides the necessary infrastructure and support for individual investigators to undertake studies of macromolecule binding and folding, as well as protein and lipid quantification. Our calorimetry instruments are fully automated and require the least amount of sample of any commercially available instruments. Specifically, we provide instrumentation and collaborative assistance for:

  • Isothermal titration calorimetry (ITC)for studying ligand-macromolecule binding
  • Differential scanning calorimetry (DSC)for investigating stability and folding thermodynamics

Our experienced staff is available to assist with project development and research.