Manyu Du
Assistant Professor of Biochemistry and Molecular Biology
-
454 Frear North
University Park, PA - mxd451@psu.edu
- 814-865-2095
Research Summary
How transcription machineries and regulatory DNA elements organize in 3D in the nucleus to regulate gene expression.
Huck Affiliations
- Center for Cellular Dynamics
- Center for Eukaryotic Gene Regulation
- Molecular, Cellular, and Integrative Biosciences
Links
Most Recent Publications
Erratum: Direct observation of a condensate effect on super-enhancer controlled gene bursting (Cell (2024) 187(2) (331–344.e17), (S0092867423013375), (10.1016/j.cell.2023.12.005))
Manyu Du, Simon Hendrik Stitzinger, Jan Hendrik Spille, Won Ki Cho, Choongman Lee, Mohammed Hijaz, Andrea Quintana, Ibrahim I. Cissé, 2024, Cell on p. 2595-2598
Direct observation of a condensate effect on super-enhancer controlled gene bursting
Manyu Du, Simon Hendrik Stitzinger, Jan Hendrik Spille, Won Ki Cho, Choongman Lee, Mohammed Hijaz, Andrea Quintana, Ibrahim I. Cissé, 2024, Cell on p. 331-344.e17
Regularly spaced tyrosines in EBF1 mediate BRG1 recruitment and formation of nuclear subdiffractive clusters
Nikolay Zolotarev, Yuanting Wang, Manyu Du, Marc Bayer, Anna Grosschedl, Ibrahim Cisse, Rudolf Grosschedl, 2024, Genes and Development on p. 4-10
Chemically Induced Chromosomal Interaction (CICI) method to study chromosome dynamics and its biological roles
Manyu Du, Fan Zou, Yi Li, Yujie Yan, Lu Bai, 2022, Nature Communications
Hijacking of transcriptional condensates by endogenous retroviruses
Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Julian Naderi, Nina Fasching, Niko Popitsch, Manyu Du, Helene Kretzmer, Zachary D. Smith, Raha Weigert, Maria Walther, Sainath Mamde, David Meierhofer, Lars Wittler, René Buschow, Bernd Timmermann, Ibrahim I. Cisse, Stefan L. Ameres, Alexander Meissner, Denes Hnisz, 2022, Nature Genetics on p. 1238-1247
Most-Cited Papers
Direct observation of a condensate effect on super-enhancer controlled gene bursting
Manyu Du, Simon Hendrik Stitzinger, Jan Hendrik Spille, Won Ki Cho, Choongman Lee, Mohammed Hijaz, Andrea Quintana, Ibrahim I. Cissé, 2024, Cell on p. 331-344.e17
Hijacking of transcriptional condensates by endogenous retroviruses
Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Julian Naderi, Nina Fasching, Niko Popitsch, Manyu Du, Helene Kretzmer, Zachary D. Smith, Raha Weigert, Maria Walther, Sainath Mamde, David Meierhofer, Lars Wittler, René Buschow, Bernd Timmermann, Ibrahim I. Cisse, Stefan L. Ameres, Alexander Meissner, Denes Hnisz, 2022, Nature Genetics on p. 1238-1247
Erratum: Direct observation of a condensate effect on super-enhancer controlled gene bursting (Cell (2024) 187(2) (331–344.e17), (S0092867423013375), (10.1016/j.cell.2023.12.005))
Manyu Du, Simon Hendrik Stitzinger, Jan Hendrik Spille, Won Ki Cho, Choongman Lee, Mohammed Hijaz, Andrea Quintana, Ibrahim I. Cissé, 2024, Cell on p. 2595-2598
Chemically Induced Chromosomal Interaction (CICI) method to study chromosome dynamics and its biological roles
Manyu Du, Fan Zou, Yi Li, Yujie Yan, Lu Bai, 2022, Nature Communications
Regularly spaced tyrosines in EBF1 mediate BRG1 recruitment and formation of nuclear subdiffractive clusters
Nikolay Zolotarev, Yuanting Wang, Manyu Du, Marc Bayer, Anna Grosschedl, Ibrahim Cisse, Rudolf Grosschedl, 2024, Genes and Development on p. 4-10