Robert Paulson

Professor of Veterinary and Biomedical Sciences

Robert Paulson

Research Summary

The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Erythropoiesis Macrophages Erythrocytes Erythropoietin Receptors Heme Inflammation Spleen Chemical Activation Ligand Time Leukemia Anemia In Vitro Techniques Erythropoietin Down Regulation Calcium Selenium Polymerization Effector Amount Regeneration Cyclopentenone Lipopolysaccharides Sphingosine Kinase Wave

Most Recent Papers

A novel clinically relevant graft-versus-leukemia model in humanized mice

Bei Jia, Chenchen Zhao, Michael Bayerl, Hiroko Shike, David F. Claxton, W. Christopher Ehmann, Shin Mineishi, Todd D. Schell, Pan Zheng, Yi Zhang, Leonard D. Shultz, K. Sandeep Prabhu, Robert F. Paulson, Hong Zheng, 2021, Journal of Leukocyte Biology

Development of SKI-349, a dual-targeted inhibitor of sphingosine kinase and microtubule polymerization

Jeremy A. Hengst, Shailaja Hegde, Robert F. Paulson, Jong K. Yun, 2020, Bioorganic and Medicinal Chemistry Letters

Stress erythropoiesis

Robert F. Paulson, Sneha Hariharan, Jane A. Little, 2020, Experimental Hematology on p. 43-54.e2

Epo receptor signaling in macrophages alters the splenic niche to promote erythroid differentiation

Yuanting Chen, Jie Xiang, Fenghua Qian, Bastihalli T. Diwakar, Baiye Ruan, Siyang Hao, K. Sandeep Prabhu, Robert F. Paulson, 2020, Blood on p. 235-246

Stress Erythropoiesis is a Key Inflammatory Response

Robert F. Paulson, Baiye Ruan, Siyang Hao, Yuanting Chen, 2020, Cells

Yap1 promotes proliferation of transiently amplifying stress erythroid progenitors during erythroid regeneration

Siyang Hao, Yurika Matsui, Zhi Chun Lai, Robert F. Paulson, 2019, Experimental Hematology on p. 42-54.e4

Crth2 receptor signaling down-regulates lipopolysaccharide-induced NF-αB activation in murine macrophages via changes in intracellular calcium

Bastihalli T. Diwakar, Ryan Yoast, Shaneice Nettleford, Fenghua Qian, Tai Jung Lee, Svanjita Berry, Ian Huffnagle, Randall M. Rossi, Mohamed Trebak, Robert F. Paulson, K. Sandeep Prabhu, 2019, FASEB Journal on p. 12838-12852

Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Laura F. Bennett, Chang Liao, Michael D. Quickel, Beng San Yeoh, Matam Vijay-Kumar, Pamela Hankey-Giblin, K. Sandeep Prabhu, Robert F. Paulson, 2019, Science's STKE : signal transduction knowledge environment

Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche

Siyang Hao, Jie Xiang, Dai Chen Wu, James W. Fraser, Baiye Ruan, Jingwei Cai, Andrew D. Patterson, Zhi Chun Lai, Robert F. Paulson, 2019, Blood advances on p. 2205-2217

Downregulation of CD73 associates with T cell exhaustion in AML patients

Yaxian Kong, Bei Jia, Chenchen Zhao, David F. Claxton, Arati Sharma, Charyguly Annageldiyev, Joseph S. Fotos, Hui Zeng, Robert F. Paulson, K. Sandeep Prabhu, Hong Zheng, 2019, Journal of Hematology and Oncology

Most-Cited Papers

In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors

Jie Xiang, Dai Chen Wu, Yuanting Chen, Robert F. Paulson, 2015, Blood on p. 1803-1812

Monocyte-derived macrophages expand the murine stress erythropoietic niche during the recovery from anemia

Chang Liao, K. Sandeep Prabhu, Robert F. Paulson, 2018, Blood on p. 2580-2593

Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Laura F. Bennett, Chang Liao, Michael D. Quickel, Beng San Yeoh, Matam Vijay-Kumar, Pamela Hankey-Giblin, K. Sandeep Prabhu, Robert F. Paulson, 2019, Science's STKE : signal transduction knowledge environment

Selenoproteins regulate stress erythroid progenitors and spleen microenvironment during stress erythropoiesis

Chang Liao, Ross C. Hardison, Mary J. Kennett, Bradley A. Carlson, Robert F. Paulson, K. Sandeep Prabhu, 2018, Blood on p. 2568-2580

Targeting a new regulator of erythropoiesis to alleviate anemia

Robert F. Paulson, 2014, Nature Medicine on p. 334-335

Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis

Janet L.Manias Rothberg, Harinad B. Maganti, Hani Jrade, Christopher J. Porter, Gareth A. Palidwor, Christopher Cafariello, Hannah L. Battaion, Safwat T. Khan, Theodore J. Perkins, Robert F. Paulson, Caryn Y. Ito, William L. Stanford, 2018, Cell Discovery

Mechanisms of erythrocyte development and regeneration

Emery H. Bresnick, Kyle J. Hewitt, Charu Mehta, Sunduz Keles, Robert F. Paulson, Kirby D. Johnson, 2018, Journal of Embryology and Experimental Morphology

Stress Erythropoiesis is a Key Inflammatory Response

Robert F. Paulson, Baiye Ruan, Siyang Hao, Yuanting Chen, 2020, Cells

Selenium suppresses leukemia through the action of endogenous eicosanoids

Ujjawal H. Gandhi, Naveen Kaushal, Shailaja Hegde, Emily R. Finch, Avinash K. Kudva, Mary J. Kennett, Craig T. Jordan, Robert F. Paulson, K. Sandeep Prabhu, 2014, Cancer Research on p. 3890-3901

Epo receptor signaling in macrophages alters the splenic niche to promote erythroid differentiation

Yuanting Chen, Jie Xiang, Fenghua Qian, Bastihalli T. Diwakar, Baiye Ruan, Siyang Hao, K. Sandeep Prabhu, Robert F. Paulson, 2020, Blood on p. 235-246