Proteomics and Mass Spectrometry hero

Proteomics and Mass Spectrometry Core Facility

Identifying and analyzing the functions of proteins using state-of-the-art mass-spectrometry instruments and techniques

The Proteomics and Mass Spectrometry Core Facility offers highly sensitive and accurate mass spectrometry analysis, including identification and quantitation of proteins by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS-MS) or by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-TOF-MS).

News

Huck seeks grad students for immersive facility assistantships

The Huck Institutes of the Life Sciences is seeking applicants for four half-time (20-hour) graduate assistantships within Huck Core Facilities during the fall 2026 semester. Graduate assistants will be placed in a single Huck core facility, chosen by the student, for hands-on experience with that facility’s technologies and applications. The assistants will contribute to projects involving the development, optimization, or application of methods and technologies within the selected facility

Undergrad research featured in American Chemical Society journal

Undergraduate students at Penn State Brandywine developed an environmentally friendly and easy method to synthesize compounds from plant-derived molecules for potential use in therapeutics. Their work, conducted under the supervision of Penn State Brandywine Assistant Professor of Chemistry Anna Sigmon, was published in a special issue of the journal American Chemical Society (ACS) Omega titled “Undergraduate Research as the Stimulus for Scientific Progress in the USA.”

Opposing forces in cells could hold clues to treating disease

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders — including cancers, neurodegenerative diseases and immune disorders — originate, as well as how to potentially treat them, according to researchers at Penn State.

Modern methods in biological research course to be offered in spring 2026

Huck Institutes of the Life Sciences core facilities are offering a new course for spring 2026, Modern Methods in Biological Research, for upper-level undergraduate students and graduate students studying in the life sciences.