Jeffrey Peters

Distinguished Professor of Molecular Toxicology and Carcinogenesis

Jeffrey Peters

Research Summary

Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.

Huck Affiliations

Links

Publication Tags

Peroxisome Proliferator Activated Receptors Ppar Delta Ligands Neoplasms Cells Carcinogenesis Tumors Choline Cell Line Cytoplasmic And Nuclear Receptors Apoptosis Chemical Activation Dietary Supplements Water Recycling Liver Rats Ppar Alpha Inflammation Tumor Microenvironment Macrophage Colony Stimulating Factor Lipid Metabolism Perfluorooctanoic Acid Lipid Droplets Sprague Dawley Rats Fatty Acid Synthases

Most Recent Papers

RESEARCH PROJECT OUTLINE

Jeffrey Peters, Gary Perdew,

Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice.

L Zhang, B Rimal, R Nichols, Y Tian, Philip Smith, E Hatzakis, S Chang, J Butenhoff, Jeffrey Peters, Andrew Patterson, 2020, Toxicology on p. 152365

Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer

Jeffrey M. Peters, Dae J. Kim, Moses T. Bility, Michael G. Borland, Bokai Zhu, Frank J. Gonzalez, 2019, Molecular Carcinogenesis on p. 1612-1622

Lipid metabolism and lipophagy in cancer

Meenu Maan, Jeffrey Maurice Peters, Mainak Dutta, Andrew David Patterson, 2018, Biochemical and Biophysical Research Communications on p. 582-589

Molecular Regulation of Carcinogenesis: Friend and Foe.

2018, Toxicological sciences : an official journal of the Society of Toxicology on p. 277-283

Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells

Michael G. Borland, Ellen M. Kehres, Christina Lee, Ashley L. Wagner, Brooke E. Shannon, Prajakta P. Albrecht, Bokai Zhu, Frank J. Gonzalez, Jeffrey M. Peters, 2018, Toxicology on p. 25-32

Perfluorooctane sulfonate-induced hepatic steatosis in male sprague dawley rats is not attenuated by dietary choline supplementation

Bradford D. Bagley, Shu Ching Chang, David J. Ehresman, Alan Eveland, Jeremiah D. Zitzow, George A. Parker, Jeffrey Maurice Peters, Kendall B. Wallace, John L. Butenhoff, 2017, Toxicological Sciences on p. 284-298

Four-week dietary supplementation with 10- and/or 15-fold basal choline caused decreased body weight in Sprague Dawley rats

Bradford D. Bagley, Shu Ching Chang, David J. Ehresman, Alan Eveland, George A. Parker, Jeffrey M. Peters, John L. Butenhoff, 2017, Toxicology and Industrial Health on p. 792-801

PPARβ/δ and PPARγ inhibit melanoma tumorigenicity by modulating inflammation and apoptosis

Michael G. Borland, Pei Li Yao, Ellen M. Kehres, Christina Lee, Amanda M. Pritzlaff, Elizabeth Ola, Ashley L. Wagner, Brooke E. Shannon, Prajakta P. Albrecht, Bokai Zhu, Boo Hyon Kang, Gavin P. Robertson, Frank J. Gonzalez, Jeffrey M. Peters, 2017, Toxicological Sciences on p. 436-448

Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation

Pei Li Yao, Liping Chen, Tomasz P. Dobrzański, Bokai Zhu, Boo Hyon Kang, Rolf Müller, Frank J. Gonzalez, Jeffrey M. Peters, 2017, Molecular Carcinogenesis on p. 1472-1483

Most-Cited Papers

NTP-CERHR expert panel report on the developmental toxicity of soy infant formula

Gail McCarver, Jatinder Bhatia, Christina Chambers, Robert Clarke, Ruth Etzel, Warren Foster, Patricia Hoyer, J. Steven Leeder, Jeffrey M. Peters, Emilie Rissman, Michael Rybak, Claire Sherman, Jorma Toppari, Katie Turner, 2011, Birth Defects Research Part B - Developmental and Reproductive Toxicology on p. 421-468

Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787

Prajakta S. Palkar, Michael G. Borland, Simone Naruhn, Christina H. Ferry, Christina Lee, Ugir H. Sk, Arun Sharma, Shantu Amin, Iain Alexander Murray, Cherie R. Anderson, Gary H. Perdew, Frank J. Gonzalez, Rolf Müller, Jeffrey Maurice Peters, 2010, Molecular pharmacology on p. 419-430

The nuclear receptor peroxisome proliferator-activated receptor-β/ δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress

Bokai Zhu, Christina H. Ferry, Lauren K. Markell, Nicholas Blazanin, Adam B. Glick, Frank J. Gonzalez, Jeffrey M. Peters, 2014, Journal of Biological Chemistry on p. 20102-20119

Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis

Tejas S. Lahoti, Jarod M. Hughes, Ann Kusnadi, Kaarthik John, Bokai Zhu, Iain A. Murray, Krishne Gowda, Jeffrey M. Peters, Shantu G. Amin, Gary H. Perdew, 2014, Journal of Pharmacology and Experimental Therapeutics on p. 236-245

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4

Combiz Khozoie, Michael G. Borland, Bokai Zhu, Songjoon Baek, Sam John, Gordon L. Hager, Yatrik M. Shah, Frank J. Gonzalez, Jeffrey M. Peters, 2012, BMC genomics

A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid

Prajakta P. Albrecht, Nicole E. Torsell, Prasad Krishnan, David J. Ehresman, Steven R. Frame, Shu Ching Chang, John L. Butenhoff, Gerald L. Kennedy, Frank J. Gonzalez, Jeffrey M. Peters, 2013, Toxicological Sciences on p. 568-582

M-CSF from cancer cells induces fatty acid synthase and PPARβ/δ activation in tumor myeloid cells, leading to tumor progression

Jonghanne Park, Sang Eun Lee, Jin Hur, Eun Byeol Hong, Jae Il Choi, Ji Min Yang, Ju Young Kim, Young Chan Kim, Hyun Jai Cho, Jeffrey Maurice Peters, Seung Bum Ryoo, Young Tae Kim, Hyo Soo Kim, 2015, Cell Reports on p. 1614-1625

Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPAR δ in inflammation-induced colon carcinogenesis

Jennifer M. Monk, Wooki Kim, Evelyn Callaway, Harmony F. Turk, Jennifer E. Foreman, Jeffrey M. Peters, Weimin He, Brad Weeks, Robert C. Alaniz, David N. McMurray, Robert S. Chapkin, 2012, American Journal of Physiology - Gastrointestinal and Liver Physiology on p. G153-G167

Ligand activation of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) inhibits cell growth in a mouse mammary gland cancer cell line

Jennifer E. Foreman, Arun Sharma, Shantu Amin, Frank J. Gonzalez, Jeffrey Maurice Peters, 2010, Cancer Letters on p. 219-225

Lipid metabolism and lipophagy in cancer

Meenu Maan, Jeffrey Maurice Peters, Mainak Dutta, Andrew David Patterson, 2018, Biochemical and Biophysical Research Communications on p. 582-589