Jeffrey Peters

Distinguished Professor of Molecular Toxicology and Carcinogenesis

Jeffrey Peters

Research Summary

Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.

Huck Affiliations

Links

Publication Tags

Peroxisome Proliferator Activated Receptors Ppar Delta Liver Ligands Choline Cells Cell Line Carcinogenesis Macrophages Perfluorooctane Sulfonic Acid Inflammation Neoplasms Cytochrome P 450 Enzyme System Chemical Activation Cytoplasmic And Nuclear Receptors Apoptosis Dietary Supplements Ions Tissue Oxidative Stress Ppar Alpha Sprague Dawley Rats Macrophage Colony Stimulating Factor Rats Breast Neoplasms

Most Recent Papers

Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer

Jeffrey M. Peters, Dae J. Kim, Moses T. Bility, Michael G. Borland, Bokai Zhu, Frank J. Gonzalez, 2019, Molecular Carcinogenesis on p. 1612-1622

Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells

Michael G. Borland, Ellen M. Kehres, Christina Lee, Ashley L. Wagner, Brooke E. Shannon, Prajakta P. Albrecht, Bokai Zhu, Frank J. Gonzalez, Jeffrey M. Peters, 2018, Toxicology on p. 25-32

Perfluorooctane sulfonate-induced hepatic steatosis in male sprague dawley rats is not attenuated by dietary choline supplementation

Bradford D. Bagley, Shu Ching Chang, David J. Ehresman, Alan Eveland, Jeremiah D. Zitzow, George A. Parker, Jeffrey Maurice Peters, Kendall B. Wallace, John L. Butenhoff, 2017, Toxicological Sciences on p. 284-298

Four-week dietary supplementation with 10- and/or 15-fold basal choline caused decreased body weight in Sprague Dawley rats

Bradford D. Bagley, Shu Ching Chang, David J. Ehresman, Alan Eveland, George A. Parker, Jeffrey M. Peters, John L. Butenhoff, 2017, Toxicology and Industrial Health on p. 792-801

PPARβ/δ and PPARγ inhibit melanoma tumorigenicity by modulating inflammation and apoptosis

Michael G. Borland, Pei Li Yao, Ellen M. Kehres, Christina Lee, Amanda M. Pritzlaff, Elizabeth Ola, Ashley L. Wagner, Brooke E. Shannon, Prajakta P. Albrecht, Bokai Zhu, Boo Hyon Kang, Gavin P. Robertson, Frank J. Gonzalez, Jeffrey M. Peters, 2017, Toxicological Sciences on p. 436-448

Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation

Pei Li Yao, Liping Chen, Tomasz P. Dobrzański, Bokai Zhu, Boo Hyon Kang, Rolf Müller, Frank J. Gonzalez, Jeffrey M. Peters, 2017, Molecular Carcinogenesis on p. 1472-1483

Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation

Joselyn N. Allen, Adwitia Dey, Ruth Nissly, James Fraser, Shan Yu, Gayathri Balandaram, Jeffrey M. Peters, Pamela A. Hankey-Giblin, 2017, Journal of Visualized Experiments

Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype

Pei Li Yao, Jose L. Morales, Frank J. Gonzalez, Jeffrey M. Peters, 2017, Immunology on p. 456-467

Regulation of cytochrome P450 2B10 (CYP2B10) expression in liver by peroxisome proliferator-activated receptor-β/δ modulation of SP1 promoter occupancy

Takayuki Koga, Pei Li Yao, Maryam Goudarzi, Iain A. Murray, Gayathri Balandaram, Frank J. Gonzalez, Gary H. Perdew, Albert J. Fornace, Jeffrey M. Peters, 2016, Journal of Biological Chemistry on p. 25255-25263

Perfluorooctane sulfonate-choline ion pair formation

Limin Zhang, Prasad Krishnan, David J. Ehresman, Philip B. Smith, Mainak Dutta, Bradford D. Bagley, Shu Ching Chang, John L. Butenhoff, Andrew D. Patterson, Jeffrey M. Peters, 2016, Toxicological Sciences on p. 186-197

Most-Cited Papers

NTP-CERHR expert panel report on the developmental toxicity of soy infant formula

Gail McCarver, Jatinder Bhatia, Christina Chambers, Robert Clarke, Ruth Etzel, Warren Foster, Patricia Hoyer, J. Steven Leeder, Jeffrey M. Peters, Emilie Rissman, Michael Rybak, Claire Sherman, Jorma Toppari, Katie Turner, 2011, Birth Defects Research Part B - Developmental and Reproductive Toxicology on p. 421-468

Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787

Prajakta S. Palkar, Michael G. Borland, Simone Naruhn, Christina H. Ferry, Christina Lee, Ugir H. Sk, Arun Sharma, Shantu Amin, Iain Alexander Murray, Cherie R. Anderson, Gary H. Perdew, Frank J. Gonzalez, Rolf Müller, Jeffrey Maurice Peters, 2010, Molecular pharmacology on p. 419-430

Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity

Pei Li Yao, Jose L. Morales, Bokai Zhu, Boo Hyon Kang, Frank J. Gonzalez, Jeffrey M. Peters, 2014, Molecular cancer therapeutics on p. 1008-1017

The nuclear receptor peroxisome proliferator-activated receptor-β/ δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress

Bokai Zhu, Christina H. Ferry, Lauren K. Markell, Nicholas Blazanin, Adam B. Glick, Frank J. Gonzalez, Jeffrey M. Peters, 2014, Journal of Biological Chemistry on p. 20102-20119

Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis

Tejas S. Lahoti, Jarod M. Hughes, Ann Kusnadi, Kaarthik John, Bokai Zhu, Iain A. Murray, Krishne Gowda, Jeffrey M. Peters, Shantu G. Amin, Gary H. Perdew, 2014, Journal of Pharmacology and Experimental Therapeutics on p. 236-245

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4

Combiz Khozoie, Michael G. Borland, Bokai Zhu, Songjoon Baek, Sam John, Gordon L. Hager, Yatrik M. Shah, Frank J. Gonzalez, Jeffrey M. Peters, 2012, BMC genomics

A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid

Prajakta P. Albrecht, Nicole E. Torsell, Prasad Krishnan, David J. Ehresman, Steven R. Frame, Shu Ching Chang, John L. Butenhoff, Gerald L. Kennedy, Frank J. Gonzalez, Jeffrey M. Peters, 2013, Toxicological Sciences on p. 568-582

M-CSF from cancer cells induces fatty acid synthase and PPARβ/δ activation in tumor myeloid cells, leading to tumor progression

Jonghanne Park, Sang Eun Lee, Jin Hur, Eun Byeol Hong, Jae Il Choi, Ji Min Yang, Ju Young Kim, Young Chan Kim, Hyun Jai Cho, Jeffrey Maurice Peters, Seung Bum Ryoo, Young Tae Kim, Hyo Soo Kim, 2015, Cell Reports on p. 1614-1625

Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPAR δ in inflammation-induced colon carcinogenesis

Jennifer M. Monk, Wooki Kim, Evelyn Callaway, Harmony F. Turk, Jennifer E. Foreman, Jeffrey M. Peters, Weimin He, Brad Weeks, Robert C. Alaniz, David N. McMurray, Robert S. Chapkin, 2012, American Journal of Physiology - Gastrointestinal and Liver Physiology on p. G153-G167

Ligand activation of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) inhibits cell growth in a mouse mammary gland cancer cell line

Jennifer E. Foreman, Arun Sharma, Shantu Amin, Frank J. Gonzalez, Jeffrey Maurice Peters, 2010, Cancer Letters on p. 219-225