Jeffrey Peters

Distinguished Professor of Molecular Toxicology and Carcinogenesis

Jeffrey Peters

Research Summary

Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.

Huck Graduate Students

Huck Affiliations

Links

Most Recent Publications

Xenobiotic Receptor-Mediated Toxicity

GH Perdew, IA Murray, JM Peters,

2023–2024 Toxicological Sciences Paper of the Year

Deborah Cory-Slechta, Jeffrey M. Peters, 2025, Toxicological Sciences on p. 1

Thank You, ToxSci 2024 Reviewers

Jeffrey M. Peters, 2024, Toxicological Sciences on p. 153-156

Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation

Shigetoshi Yokoyama, Imhoi Koo, Daisuke Aibara, Yuan Tian, Iain Alexander Murray, Stephanie L. Collins, Denise M. Coslo, Mari Kono, Jeffrey Maurice Peters, Richard L. Proia, Frank J. Gonzalez, Gary H. Perdew, Andrew D. Patterson, 2024, Advanced Science on p. e2400794

Chlorpyrifos modulates the mouse gut microbiota and metabolic activity

Robert G. Nichols, Bipin Rimal, Fuhua Hao, Jeffrey Maurice Peters, Emily R. Davenport, Andrew D. Patterson, 2024, Environmental International on p. 109022

Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) in Keratinocytes by Endogenous Fatty Acids

Bokai Zhu, Xiaoyang Zhu, Michael G. Borland, Douglas H. Ralph, Christopher R. Chiaro, Kristopher W. Krausz, James M. Ntambi, Adam B. Glick, Andrew D. Patterson, Gary H. Perdew, Frank J. Gonzalez, Jeffrey M. Peters, 2024, Biomolecules

2022-2023 Toxicological Sciences: Paper of the Year

Yvonne Will, Jeffrey M. Peters, 2024, Toxicological Sciences on p. 2-3

Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice

Xiaoyang Zhu, Qing Liu, Andrew D. Patterson, Arun K. Sharma, Shantu G. Amin, Samuel M. Cohen, Frank J. Gonzalez, Jeffrey M. Peters, 2023, Metabolites

2021-2022 Toxicological Sciences paper of the year

Lei Guo, Jeffrey Peters, 2023, Toxicological Sciences on p. 1--2

Cannabidiolic acid activates the expression of the PPARβ/δ target genes in MDA-MB-231 cells

Masayo Hirao-Suzuki, Koga Takayuki, Masufumi Takiguchi, Jeffrey M. Peters, Shuso Takeda, 2022, Archives of Biochemistry and Biophysics

Most-Cited Papers

Lipid metabolism and lipophagy in cancer

Meenu Maan, Jeffrey Peters, Mainak Dutta, Andrew D. Patterson, 2018, Biochemical and Biophysical Research Communications on p. 582--589

The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions

J. Christopher Corton, Jeffrey M. Peters, James E. Klaunig, 2018, Archiv fur Toxikologie on p. 83-119

M-CSF from cancer cells induces fatty acid synthase and PPARβ/δ activation in tumor myeloid cells, leading to tumor progression

Jonghanne Park, Sang Eun Lee, Jin Hur, Eun Byeol Hong, Jae Il Choi, Ji Min Yang, Ju Young Kim, Young Chan Kim, Hyun Jai Cho, Jeffrey M. Peters, Seung Bum Ryoo, Young Tae Kim, Hyo Soo Kim, 2015, Cell Reports on p. 1614-1625

Establishing the Role of PPARβ/δ in Carcinogenesis

Jeffrey M. Peters, Frank J. Gonzalez, Rolf Müller, 2015, Trends in Endocrinology and Metabolism on p. 595-607

Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice

Limin Zhang, Bipin Rimal, Robert Nichols, Yuan Tian, Philip B. Smith, Emmanuel Hatzakis, Shu-Ching Chang, John Butenhoff, Jeffrey Peters, Andrew D. Patterson, 2020, Toxicology on p. 152365

Interplay Between the Host, the Human Microbiome, and Drug Metabolism

Robert Nichols, Jeffrey Peters, Andrew D. Patterson, 2019, Human Genomics on p. 1--10

Current Challenges and Recent Developments in Mass Spectrometry-Based Metabolomics

Stephanie Collins, Imhoi Koo, Jeffrey Peters, Philip B. Smith, Andrew D. Patterson, 2021, Annual Review of Analytical Chemistry on p. 467--487

The Evolution of Carcinogenesis

Jeffrey M. Peters, Frank J. Gonzalez, 2018, Toxicological Sciences on p. 272-276

PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration

Mayur Choudhary, Jin dong Ding, Xiaoping Qi, Michael E. Boulton, Pei Li Yao, Jeffrey M. Peters, Goldis Malek, 2016, Aging on p. 1952-1978

Molecular Regulation of Carcinogenesis: Friend and Foe

Andrew D. Patterson, Frank Gonzalez, Gary Perdew, Jeffrey Peters, 2018, Toxicological Sciences on p. 277--283