Jeffrey Peters
Distinguished Professor of Molecular Toxicology and Carcinogenesis
-
312 Huck Life Sciences
University Park, PA 16802 - jmp21@psu.edu
- 814-863-1387
Research Summary
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.
Huck Graduate Students
Huck Affiliations
Links
Publication Tags
These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.
Peroxisome Proliferator Activated Receptors Neoplasms Liver Pharmacological Metabolism Peroxisome Proliferator Activated Receptor Cytoplasmic And Nuclear Receptors Tumors Ppar Alpha Fatty Acid Weight Dose Industrial Substance Sulfonate Perfluorooctane Sulfonic Acid Macrophage Colony Stimulating Factor Perfluorooctane Fatty Acid Synthases Cannabidiolic Acid Fatty Acid Synthase Drug Rodentia Ligands Mass Spectrometry Oxidative Stress GenesMost Recent Publications
Xenobiotic Receptor-Mediated Toxicity
GH Perdew, IA Murray, JM Peters,
Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) in Keratinocytes by Endogenous Fatty Acids
Bokai Zhu, Xiaoyang Zhu, Michael G. Borland, Douglas H. Ralph, Christopher R. Chiaro, Kristopher W. Krausz, James M. Ntambi, Adam B. Glick, Andrew D. Patterson, Gary H. Perdew, Frank J. Gonzalez, Jeffrey M. Peters, 2024, Biomolecules
2022-2023 Toxicological Sciences: Paper of the Year
Yvonne Will, Jeffrey M. Peters, 2024, Toxicological Sciences on p. 2-3
Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice
Xiaoyang Zhu, Qing Liu, Andrew D. Patterson, Arun K. Sharma, Shantu G. Amin, Samuel M. Cohen, Frank J. Gonzalez, Jeffrey M. Peters, 2023, Metabolites
2021-2022 Toxicological Sciences paper of the year
Lei Guo, Jeffrey Peters, 2023, Toxicological Sciences on p. 1--2
Cannabidiolic acid activates the expression of the PPARβ/δ target genes in MDA-MB-231 cells
Masayo Hirao-Suzuki, Koga Takayuki, Masufumi Takiguchi, Jeffrey M. Peters, Shuso Takeda, 2022, Archives of Biochemistry and Biophysics
The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice
S Su, Laura Billy, Sue Chang, Frank Gonzalez, Andrew D. Patterson, Jeffrey Peters, 2022, Toxicology on p. 153056
Targeting peroxisome proliferator-activated receptor-β/δ (pparβ/δ) for the treatment or prevention of alcoholic liver disease
Takayuki Koga, Jeffrey M. Peters, 2021, Biological and Pharmaceutical Bulletin on p. 1598-1606
Diminished Hepatocarcinogenesis by a Potent, High-Affinity Human PPARα Agonist in PPARA-Humanized Mice
Jennifer E. Foreman, Takayuki Koga, Oksana Kosyk, Boo Hyon Kang, Xiaoyang Zhu, Samuel M. Cohen, Laura J. Billy, Arun K. Sharma, Shantu Amin, Frank J. Gonzalez, Ivan Rusyn, Jeffrey M. Peters, 2021, Toxicological Sciences on p. 70--80
Current Challenges and Recent Developments in Mass Spectrometry-Based Metabolomics
Stephanie Collins, Imhoi Koo, Jeffrey Peters, Philip B. Smith, Andrew D. Patterson, 2021, Annual Review of Analytical Chemistry on p. 467--487
Most-Cited Papers
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study
J. Christopher Corton, Michael L. Cunningham, B. Timothy Hummer, Christopher Lau, Bette Meek, Jeffrey M. Peters, James A. Popp, Lorenz Rhomberg, Jennifer Seed, James E. Klaunig, 2014, Critical Reviews in Toxicology on p. 1-49
Lipid metabolism and lipophagy in cancer
Meenu Maan, Jeffrey Peters, Mainak Dutta, Andrew D. Patterson, 2018, Biochemical and Biophysical Research Communications on p. 582--589
The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions
J. Christopher Corton, Jeffrey M. Peters, James E. Klaunig, 2018, Archiv fur Toxikologie on p. 83-119
M-CSF from cancer cells induces fatty acid synthase and PPARβ/δ activation in tumor myeloid cells, leading to tumor progression
Jonghanne Park, Sang Eun Lee, Jin Hur, Eun Byeol Hong, Jae Il Choi, Ji Min Yang, Ju Young Kim, Young Chan Kim, Hyun Jai Cho, Jeffrey M. Peters, Seung Bum Ryoo, Young Tae Kim, Hyo Soo Kim, 2015, Cell Reports on p. 1614-1625
Establishing the Role of PPARβ/δ in Carcinogenesis
Jeffrey M. Peters, Frank J. Gonzalez, Rolf Müller, 2015, Trends in Endocrinology and Metabolism on p. 595-607
Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity
Pei Li Yao, Jose L. Morales, Bokai Zhu, Boo Hyon Kang, Frank J. Gonzalez, Jeffrey M. Peters, 2014, Molecular Cancer Therapeutics on p. 1008-1017
Interplay Between the Host, the Human Microbiome, and Drug Metabolism
Robert Nichols, Jeffrey Peters, Andrew D. Patterson, 2019, Human Genomics on p. 1--10
Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice
Limin Zhang, Bipin Rimal, Robert Nichols, Yuan Tian, Philip B. Smith, Emmanuel Hatzakis, Shu-Ching Chang, John Butenhoff, Jeffrey Peters, Andrew D. Patterson, 2020, Toxicology on p. 152365
The Evolution of Carcinogenesis
Jeffrey M. Peters, Frank J. Gonzalez, 2018, Toxicological Sciences on p. 272-276
The nuclear receptor peroxisome proliferator-activated receptor-β/ δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress
Bokai Zhu, Christina H. Ferry, Lauren K. Markell, Nicholas Blazanin, Adam B. Glick, Frank J. Gonzalez, Jeffrey M. Peters, 2014, Journal of Biological Chemistry on p. 20102-20119
News Articles Featuring Jeffrey Peters
Sep 02, 2022
Metabolomics Core Facility continues to expand while pushing scientific bounds
Established nearly a decade ago, Penn State’s Metabolomics Core Facility is housed in the Huck Institutes of the Life Sciences on the University Park campus.
Full Article
Jan 21, 2020
Persistent environmental contaminant changes the gut microbiome of mice
An industrial chemical — phased out since 2002, but previously used in stain and water-repellent products and firefighting foam — alters the gut microbiome of mice and could have implications for human health, according to an international team of researchers.
Full Article