Simple drug combination creates new neurons from neighboring cells
A simple drug cocktail that converts cells neighboring damaged neurons into functional new neurons could potentially be used to treat stroke, Alzheimer’s disease, and brain injuries. A team of researchers at Penn State identified a set of four, or even three, molecules that could convert glial cells—which normally provide support and insulation for neurons—into new neurons.
Melik Demirel named Huck Chair in Biomimetic Materials
Melik C. Demirel, professor of engineering science and mechanics at Penn State, was recently named Lloyd and Dorothy Foehr Huck Chair in Biomimetic Materials by the University’s Huck Institutes of the Life Sciences.
Differences in genes’ geographic origin influence mitochondrial function
Differences in the geographic origin of genes may affect the function of human mitochondria — energy-generating organelles inside of cells — according to a new study. Mitochondria have their own genome, separate from the nuclear genome contained in the nucleus of the cell, and both genomes harbor genes integral to energy production by mitochondria. The study explores whether these “mito-nuclear” interactions, which are fine-tuned by natural selection over deep evolutionary time, could be altered when genes of different geographic origins are brought together within a genome.
Feb 13, 2019
New method uses fluorescence to identify disease-causing forms of proteins
A new method uses fluorescence to detect potentially disease-causing forms of proteins as they unravel due to stress or mutations. A team of researchers from Penn State and the University of Washington reengineered a fluorescent compound and developed a method to simultaneously light up two different proteins as they misfold and aggregate inside a living cell, highlighting forms that likely play a role in several neurodegenerative diseases including Alzheimer’s and Parkinson’s.
Feb 13, 2019
Troy Ott to discuss "the improbable series of events that led to your birth"
At this month’s "Science on Tap" event, Huck Associate Director and professor of reproductive biology Troy Ott will discuss viviparity — the development of an embryo inside the body leading to the birth of a live offspring. Viviparity is thought to have evolved from egg-laying animals. Ott's talk will focus on one of the enigmas of live birth that relates to the mother’s immune system.
Feb 11, 2019
Toward automated animal identification in wildlife research
A new automated method to prepare digital photos for analysis will help wildlife researchers who depend on photographs to identify individual animals by their unique markings. A wildlife biologist from Penn State teamed up with scientists from Microsoft Azure, a cloud computing service, using machine learning technology to improve how photographs are turned into usable data for wildlife research. A paper describing the new technique appears online in the journal Ecological Informatics.
Center for Infectious Disease Dynamics
Volatile-mediated Inhibition and Recognition Between Soilborne Fungal Pathogens and Trichoderma Biocontrol Agents
CSL Behring Fermentation Facility Tour
Center of Excellence in Industrial Biotechnology