Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology

Scott Showalter

Research Summary

Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Huck Affiliations


Publication Tags

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Proteins Protein Intrinsically Disordered Proteins Phosphorylation Nmr Spectroscopy Magnetic Resonance Spectroscopy Nuclear Magnetic Resonance Rna Polymerase Ii Rna Application Lysine Carbon Nuclear Magnetic Resonance Spectroscopy Proline Modification Switches Cyclic Amp Dependent Protein Kinases Lanthanoid Series Elements Masks Acetylation Rna Polymerase Iii Epitopes Proteome Viral Proteins Gene Expression

Most Recent Publications

Kevin E.W. Namitz, Scott A. Showalter, Michael S. Cosgrove, 2023, Journal of Biological Chemistry

Olivia A. Fraser, Kevin E.W. Namitz, Scott A. Showalter, 2023, ImmunoMethods on p. 72-83

Wei Chen, Oluwadamilare Aboyewa, Scott A. Showalter, 2023, Biophysical Journal on p. 202a

Olivia A. Fraser, Sophia M. Dewing, Emery T. Usher, Christy George, Scott A. Showalter, 2023, Frontiers in Molecular Biosciences

Emery T. Usher, Scott A. Showalter, 2022, Journal of Biological Chemistry

Emery T. Usher, Kevin E.W. Namitz, Michael S. Cosgrove, Scott A. Showalter, 2021, Biophysical Journal on p. 4710-4721

Transient Electrostatic Interactions between Fcp1 and Rap74 Bias the Conformational Ensemble of the Complex with Minimal Impact on Binding Affinity

Victor A. Prieto, Kevin E.W. Namitz, Scott A. Showalter, 2021, Journal of Physical Chemistry B on p. 10917-10927

Emery T. Usher, Nafiseh Sabri, Roman Rohac, Amie K. Boal, Tanja Mittag, Scott A. Showalter, 2021, Journal of Biological Chemistry

Emery T. Usher, Scott A. Showalter, 2020, Journal of Biological Chemistry on p. 17411-17412

Suzette A. Pabit, Yen Lin Chen, Emery T. Usher, Erik C. Cook, Lois Pollack, Scott A. Showalter, 2020, Biophysical Journal on p. 2524-2536

Most-Cited Papers

Structural Basis for Rare Earth Element Recognition by Methylobacterium extorquens Lanmodulin

Erik C. Cook, Emily R. Featherston, Scott A. Showalter, Joseph A. Cotruvo, 2019, Biochemistry on p. 120-125

Eric B. Gibbs, Erik C. Cook, Scott A. Showalter, 2017, Archives of Biochemistry and Biophysics on p. 57-70

Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature Communications

Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour, 2017, Nature Communications

Quantitative biophysical characterization of intrinsically disordered proteins

Eric B. Gibbs, Scott A. Showalter, 2015, Biochemistry on p. 1314-1326

Debashish Sahu, Monique Bastidas, Scott A. Showalter, 2014, Analytical Biochemistry on p. 17-25

A primer for carbon-detected NMR applications to intrinsically disordered proteins in solution

Monique Bastidas, Eric B. Gibbs, Debashish Sahu, Scott A. Showalter, 2015, Concepts in Magnetic Resonance Part A: Bridging Education and Research on p. 54-66

Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks

Janna Sloand, Janna Sloand^, Eric Cook, Theodore Nguyen, Scott A. Zinck, Tawanda Zimudzi, Erik C. Cook, Scott Zinck, S Showalter, Tawanda J. Zimudzi, Scott Schowalter, Scott A. Showalter, Julianna Simon, S Medina, Adam B. Glick, Julianna Simon, Scott Medina*, 2020, ACS Nano on p. 4061-4073

Role of ordered proteins in the folding-upon-binding of intrinsically disordered proteins

Chad W. Lawrence, Sushant Kumar, William G. Noid, Scott A. Showalter, 2014, Journal of Physical Chemistry Letters on p. 833-838

Daniel G. Cordek, Tayler J. Croom-Perez, Jungwook Hwang, Michele R.S. Hargittai, Chennareddy V. Subba-Reddy, Qingxia Han, Maria Fernanda Lodeiro, Gang Ning, Thomas S. McCrory, Jamie J. Arnold, Hasan Koc, Brett D. Lindenbach, Scott A. Showalter, Craig E. Cameron, 2014, Journal of Biological Chemistry on p. 24397-24416