Denise Okafor

Huck Early Career Chair in Biophysics, Assistant Professor of Biochemistry and Molecular Biology

Denise Okafor

Research Summary

Structural mechanisms of signaling and regulation in protein complexes.

Huck Affiliations


Publication Tags

These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.

Ligands Cytoplasmic And Nuclear Receptors Proteins Liver Steroid Receptors Transcription Factors Protein Agonist Dna Therapeutics Molecular Dynamics Simulation Enzymes Hormone Dna Binding Proteins Rna Plasmodium Phospholipids Parasites Glucocorticoid Receptors Steroid Antimalarials Gene Expression Crystal Structure Orphan Nuclear Receptors Iron

Most Recent Publications

Sabab Hasan Khan, Namita Dube, Nishanti Sudhakar, Olivia Fraser, Priscilla Villalona, Sean M. Braet, Stephanie Leedom, Erin R. Reilly, Jacob Sivak, Kenidee Crittenden, C. Denise Okafor, 2024, RSC Chemical Biology on p. 518-529

Saurov Hazarika, Matthew Fehrle, C. Denise Okafor, 2024, Journal of Chemical Physics

Nathaniel R. Glasser, Dongtao Cui, Douglas D. Risser, C. Denise Okafor, Emily P. Balskus, 2024, Nature Chemistry on p. 173-182

Suzanne G. Mays, David Hercules, Eric A. Ortlund, C. Denise Okafor, 2023, Protein Science

Ericka D. Surrett, Kirsten R. Guckes, Shyan Cousins, Terry B. Ruskoski, Andrew G. Cecere, Denise A. Ludvik, C. Denise Okafor, Mark J. Mandel, Tim I. Miyashiro, 2023, eLife

Namita Dube, Sabab Hasan Khan, Riley Sasse, C. Denise Okafor, 2023, Journal of Chemical Information and Modeling on p. 571-582

Interactions governing transcriptional activity of nuclear receptors

Sabab Hasan Khan, C. Denise Okafor, 2022, Biochemical Society Transactions on p. 1941-1952

Timothy James Russell, Erandi K. De Silva, Valerie M. Crowley, Kathryn Shaw-Saliba, Namita Dube, Gabrielle Josling, Charisse Flerida A. Pasaje, Irene Kouskoumvekaki, Gianni Panagiotou, Jacquin C. Niles, Marcelo Jacobs-Lorena, C. Denise Okafor, Francisco Javier Gamo, Manuel Llinás, 2022, PLoS Pathogens

Suzanne G. Mays, Emma H. D'Agostino, Autumn R. Flynn, Xiangsheng Huang, Guohui Wang, Xu Liu, Elizabeth J. Millings, C. Denise Okafor, Anamika Patel, Michael L. Cato, Jeffery L. Cornelison, Diana Melchers, René Houtman, David D. Moore, John W. Calvert, Nathan T. Jui, Eric A. Ortlund, 2022, Cell Chemical Biology on p. 1174-1186.e7

Structural and Biophysical Mechanisms Driving Differential Hormone Response in Steroid Receptors

Sabab H. Khan, Sean M. Braet, Stephen J. Koehler, Elizabeth Elacqua, Ganesh S. Anand, Denise Okafor, 2022, FASEB Journal

Most-Cited Papers

Bile acids and the gut microbiota: metabolic interactions and impacts on disease

S Collins, Jonathan Stine, Jordan E. Bisanz, C. Denise Okafor, D Okafor, Andrew Patterson, 2022, Nature Reviews Microbiology on p. 236-247

M McBride, S Pope, K Hu, C. Denise Okafor, C Denise Okafor, E Balskus, J Bollinger, J. Martin Bollinger, Amie K. Boal, 2021, Proceedings of the National Academy of Sciences of the United States of America

Burak Gulen, Anton S. Petrov, C. Denise Okafor, Drew Vander Wood, Eric B. O'Neill, Nicholas V. Hud, Loren Dean Williams, 2016, Scientific Reports

Suzanne G. Mays, C. Denise Okafor, Richard J. Whitby, Devrishi Goswami, Józef Stec, Autumn R. Flynn, Michael C. Dugan, Nathan T. Jui, Patrick R. Griffin, Eric A. Ortlund, 2016, Journal of Biological Chemistry on p. 25281-25291

C. Denise Okafor, Kathryn A. Lanier, Anton S. Petrov, Shreyas S. Athavale, Jessica C. Bowman, Nicholas V. Hud, Loren Dean Williams, 2017, Nucleic Acids Research on p. 3634-3642

C. Denise Okafor, Manish C. Pathak, Crystal E. Fagan, Nicholas C. Bauer, Megan F. Cole, Eric A. Gaucher, Eric A. Ortlund, 2018, Structure with Folding & design on p. 118-129.e3

Suzanne G. Mays, Autumn R. Flynn, Jeffery L. Cornelison, C. Denise Okafor, Hongtao Wang, Guohui Wang, Xiangsheng Huang, Heather N. Donaldson, Elizabeth J. Millings, Rohini Polavarapu, David D. Moore, John W. Calvert, Nathan T. Jui, Eric A. Ortlund, 2019, Journal of Medicinal Chemistry on p. 11022-11034

Emily R. Weikum, C. Denise Okafor, Emma H. D'Agostino, Jennifer K. Colucci, Eric A. Ortlund, 2017, Molecular Pharmacology on p. 12-21

Suzanne G. Mays, C. Denise Okafor, Micheal L. Tuntland, Richard J. Whitby, Venkatasubramanian Dharmarajan, Józef Stec, Patrick R. Griffin, Eric A. Ortlund, 2017, Molecular Pharmacology on p. 1-11

News Articles Featuring Denise Okafor

Denise Okafor named Huck Early Career Chair in Biophysics

Denise Okafor, assistant professor of biochemistry and molecular biology in the Eberly College of Science at Penn State, has been awarded a Dorothy Foehr Huck and J. Lloyd Huck Early Career Chair in Biophysics.

731: Investigating the Mechanisms of Signaling and Regulation in Protein Complexes - Dr. Denise Okafor

Learn more about the research and life of Denise Okafor

Bioluminescent bacteria coordinate signaling to colonize squid’s light organ

Bioluminescent bacteria and the Hawaiian bobtail squid have formed a longstanding mutually beneficial relationship.

Penn State biochemist Denise Okafor receives 2023 Marion Milligan Mason Award

C. Denise Okafor, assistant professor of biochemistry and molecular biology and of chemistry at Penn State, has been selected as a recipient of the 2023 Marion Milligan Mason Award for Women in the Chemical Sciences by the American Association for the Advancement of Science (AAAS).

Okafor receives 2021 National Science Foundation CAREER Award

C. Denise Okafor, assistant professor of biochemistry and molecular biology, has been honored with a Faculty Early Career Development award from the U.S. National Science Foundation. The award is the NSF’s most prestigious honor in support of early-career faculty members who have the potential to serve as academic role models.