artist's rendering of neurons

Neuroscience

Probe the complexities of the nervous system from the standpoint of molecular research to clinical practice

News

Novel biogel may solve a hairy problem for wearable brain-monitoring systems

A vital tool for healthcare practitioners, electroencephalography (EEG) systems measure electrical activity in the brain through electrodes placed on the scalp, but getting reliable readings can be surprisingly difficult. Hair interferes with contact between the electrodes and skin, and the gels used to improve those connections often dry out over time, weakening signal quality. Researchers at Penn State have developed a reusable material designed to solve both problems at once. The material is a thermoreversible semiconducting ionic biogel, meaning it becomes liquid when gently heated so it can move through hair and reach the scalp, then returns to a stable gel as it cools, keeping its conducting and semiconducting character.

$3M NIH grant to support research on memory and exaggerated fear responses

Experiencing a traumatic event sometimes produces long-lasting biological changes that can lead to an exaggerated fear response to future stressful events, such as what occurs in individuals with post-traumatic stress disorder. To better understand the regulatory mechanisms in the brain that produce this biological memory and exaggerated fear response, a team of researchers from Penn State and the University of Wisconsin-Milwaukee has been awarded a grant from the U.S. National Institutes of Health’s National Institute of Mental Health.

Dipanjan Pan named Huck director for innovation and entrepreneurship ecosystems

Penn State’s Huck Institutes of the Life Sciences has named Dipanjan Pan, Dorothy Foehr Huck & J. Lloyd Huck Chair Professor in Nanomedicine and professor of materials science and engineering and of nuclear engineering, to serve as the Huck’s first director for innovation and entrepreneurship ecosystems.

News

Novel biogel may solve a hairy problem for wearable brain-monitoring systems

A vital tool for healthcare practitioners, electroencephalography (EEG) systems measure electrical activity in the brain through electrodes placed on the scalp, but getting reliable readings can be surprisingly difficult. Hair interferes with contact between the electrodes and skin, and the gels used to improve those connections often dry out over time, weakening signal quality. Researchers at Penn State have developed a reusable material designed to solve both problems at once. The material is a thermoreversible semiconducting ionic biogel, meaning it becomes liquid when gently heated so it can move through hair and reach the scalp, then returns to a stable gel as it cools, keeping its conducting and semiconducting character.

$3M NIH grant to support research on memory and exaggerated fear responses

Experiencing a traumatic event sometimes produces long-lasting biological changes that can lead to an exaggerated fear response to future stressful events, such as what occurs in individuals with post-traumatic stress disorder. To better understand the regulatory mechanisms in the brain that produce this biological memory and exaggerated fear response, a team of researchers from Penn State and the University of Wisconsin-Milwaukee has been awarded a grant from the U.S. National Institutes of Health’s National Institute of Mental Health.

Dipanjan Pan named Huck director for innovation and entrepreneurship ecosystems

Penn State’s Huck Institutes of the Life Sciences has named Dipanjan Pan, Dorothy Foehr Huck & J. Lloyd Huck Chair Professor in Nanomedicine and professor of materials science and engineering and of nuclear engineering, to serve as the Huck’s first director for innovation and entrepreneurship ecosystems.

How can the same genetic mutation lead to different clinical outcomes?

Individuals that share the same deletion of a portion of chromosome 16 are at risk of developing neurodevelopmental disorders, but some experience severe intellectual disability or developmental delay, while others may only exhibit milder psychiatric features like depression or anxiety. How can this be? To answer this, a team led by Penn State scientists has developed methods to evaluate how genetic variants elsewhere in an individual’s genome work with the deletion to help determine the features that the individual will manifest.