Urara Hasegawa

Assistant Professor of Materials Science and Engineering

Urara Hasegawa

Research Summary

The development of polymeric nanomaterials for controlled delivery of drug and bioactive signaling molecules

Huck Affiliations

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Publication Tags

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Micelles Hydrogen Sulfide Nanoparticles Micelle Benzeneboronic Acid Nanoparticle Acids Anethole Carbon Monoxide Reactive Oxygen Species Antioxidants Hydrolysis Catechol Polyethylene Glycols Polymerization Therapeutics Curcumin Water Cells Membranes Donor Neoplasms Endothelial Cells Proteins Macrophages

Most Recent Publications

Adsorption of CO<sub>2</sub> by Amine-Functionalized Metal-Organic Frameworks Using GCMC and ReaxFF-Based Metadynamics Simulations

Yongjian Yang, Yun Kyung Shin, Hideaki Ooe, Urara Hasegawa, Setsuko Yamane, Hayata Yamada, Adri C.T. van Duin, Yasuhiro Murase, John C. Mauro, 2024, Journal of Physical Chemistry C on p. 5257-5270

Recent advance in self-assembled polymeric nanomedicines for gaseous signaling molecule delivery

André J. van der Vlies, Setsuko Yamane, Urara Hasegawa, 2024, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Biobased Semi-Interpenetrating Polymer Networks of Poly(ϵ-caprolactone) and Epoxidized Soybean Oil with Nanoscale Morphology, Shape-Memory Effect, and Biocompatibility

Samy A. Madbouly, Setsuko Yamane, André J.van der Vlies, Urara Hasegawa, 2023, ACS Applied Polymer Materials on p. 8907-8918

Functionalization of Framboidal Phenylboronic Acid-Containing Nanoparticles via Aqueous Suzuki–Miyaura Coupling Reactions

André J. van der Vlies, Urara Hasegawa, 2023, Molecules

Manganese Porphyrin-Containing Polymeric Micelles: A Novel Approach for Intracellular Catalytic Formation of Per/Polysulfide Species from a Hydrogen Sulfide Donor

Kemper Young, Setsuko Yamane, Elmira Abbasi GharehTapeh, Shingo Kasamatsu, Hideshi Ihara, Urara Hasegawa, 2023, Advanced healthcare materials

Controlled Dissociation of Polymeric Micelles in Response to Oxidative Stress

Roujia Chang, Binru Han, Amira Ben Mabrouk, Urara Hasegawa, 2023, Biomacromolecules

Reactive Oxygen Species-Triggered Hydrogen Sulfide Release and Cancer-Selective Antiproliferative Effect of Anethole Dithiolethione-Containing Polymeric Micelles

André J. van der Vlies, Masoud Ghasemi, Bernadette M. Adair, James H. Adair, Enrique Daniel Gomez, Urara Hasegawa, 2023, Advanced healthcare materials

Mechanical loading of intraluminal pressure mediates wound angiogenesis by regulating the TOCA family of F-BAR proteins

Shinya Yuge, Koichi Nishiyama, Yuichiro Arima, Yasuyuki Hanada, Eri Oguri-Nakamura, Sanshiro Hanada, Tomohiro Ishii, Yuki Wakayama, Urara Hasegawa, Kazuya Tsujita, Ryuji Yokokawa, Takashi Miura, Toshiki Itoh, Kenichi Tsujita, Naoki Mochizuki, Shigetomo Fukuhara, 2022, Nature Communications

Launching my own lab in the US

Urara Hasegawa, 2022, Kobunshi on p. 169

Thioether-Based Polymeric Micelles with Fine-Tuned Oxidation Sensitivities for Chemotherapeutic Drug Delivery

André J. Van Der Vlies, van der Vlies, Andre J., Van Der Vlies, Andr\'e J, Jiayi Xu, Masoud Ghasemi, Carol Bator, Amanda Bell, Brett Rosoff-Verbit, Bin Liu, Enrique D. Gomez, Urara Hasegawa, 2021, Biomacromolecules on p. 77--88

Most-Cited Papers

Design and synthesis of polymeric hydrogen sulfide donors

Urara Hasegawa, André J. Van Der Vlies, 2014, Bioconjugate Chemistry on p. 1290-1300

Facile fabrication of poly(methyl methacrylate) monolith via thermally induced phase separation by utilizing unique cosolvency

Shinya Yoneda, Wenjuan Han, Urara Hasegawa, Hiroshi Uyama, 2014, Polymer on p. 3212-3216

Polymeric Framboidal Nanoparticles Loaded with a Carbon Monoxide Donor via Phenylboronic Acid-Catechol Complexation

André J. Van Der Vlies, Ryosuke Inubushi, Hiroshi Uyama, Urara Hasegawa, 2016, Bioconjugate Chemistry on p. 1500-1508

Dual Stimuli-Responsive Phenylboronic Acid-Containing Framboidal Nanoparticles by One-Step Aqueous Dispersion Polymerization

Urara Hasegawa, Tomoki Nishida, André J. Van Der Vlies, 2015, Macromolecules on p. 4388-4393

Polymeric micelles for hydrogen sulfide delivery

Urara Hasegawa, André J. Van Der Vlies, 2015, MedChemComm on p. 273-276

Framboidal Nanoparticles Containing a Curcumin-Phenylboronic Acid Complex with Antiangiogenic and Anticancer Activities

André J. Van Der Vlies, Manami Morisaki, Hoi I. Neng, Emma M. Hansen, Urara Hasegawa, 2019, Bioconjugate Chemistry on p. 861-870

Mitochondria-Targeting Polyamine–Protoporphyrin Conjugates for Photodynamic Therapy

Fargol Taba, Akira Onoda, Urara Hasegawa, Toshiaki Enoki, Yousuke Ooyama, Joji Ohshita, Takashi Hayashi, 2018, Farmaco on p. 15-19

Hydrolysis-Sensitive Dithiolethione Prodrug Micelles

Urara Hasegawa, Naoya Tateishi, Hiroshi Uyama, André J. Van Der Vlies, 2015, Macromolecular Bioscience on p. 1512-1522

Inhibition of Angiogenesis by Antioxidant Micelles

Masaki Moriyama, Stéphanie Metzger, André J. van der Vlies, Hiroshi Uyama, Martin Ehrbar, Urara Hasegawa, 2015, Advanced healthcare materials on p. 569-575

Hydrogen sulfide-releasing micelles for promoting angiogenesis

Jerry J.Y. Chen, André J. Van Der Vlies, Urara Hasegawa, 2020, Polymer Chemistry on p. 4454-4463