Idan Shalev

Assistant Professor of Biobehavioral Health

Idan Shalev

Research Summary

Interdisciplinary approach to identify mechanisms underpinning the biological embedding of stress across the lifespan with a special focus on biological aging.

Huck Graduate Students

Huck Affiliations

Publication Tags

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Telomere Child Dna Methylation Caloric Restriction Health Childhood Biomarkers Cellular Senescence Mental Disorders Genes Epigenomics Psychiatry Exposure To Violence Population Psychopathology Longevity Obesity Research Therapeutics Aptitude Mental Disorder Prospective Studies Telomere Shortening Longitudinal Studies Violence

Most Recent Publications

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

R. Waziry, C. P. Ryan, D. L. Corcoran, K. M. Huffman, M. S. Kobor, M. Kothari, G. H. Graf, V. B. Kraus, W. E. Kraus, D. T.S. Lin, C. F. Pieper, M. E. Ramaker, M. Bhapkar, S. K. Das, L. Ferrucci, W. J. Hastings, M. Kebbe, D. C. Parker, S. B. Racette, I. Shalev, B. Schilling, D. W. Belsky, 2023, Nature Aging

Investigating the effects of maltreatment and acute stress on the concordance of blood and DNA methylation methods of estimating immune cell proportions

Abner Apsley, Laura Etzel, Waylon J. Hastings, Christine C. Heim, Jennie G. Noll, Kieran J. O’Donnell, Kieran O'Donnell, Hannah Schreier, Chad E. Shenk, Qiaofeng Ye, Idan Shalev, 2023, Clinical Epigenetics

Author Correction: Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (Nature Aging, (2023), 3, 3, (248-257), 10.1038/s43587-022-00357-y)

R. Waziry, C. P. Ryan, D. L. Corcoran, K. M. Huffman, M. S. Kobor, M. Kothari, G. H. Graf, V. B. Kraus, W. E. Kraus, D. T.S. Lin, C. F. Pieper, M. E. Ramaker, M. Bhapkar, S. K. Das, L. Ferrucci, W. J. Hastings, M. Kebbe, D. C. Parker, S. B. Racette, I. Shalev, B. Schilling, D. W. Belsky, 2023, Nature Aging

Attachment insecurity and the biological embedding of reproductive strategies: Investigating the role of cellular aging

Emma Bolhuis, Jay Belsky, Willem E. Frankenhuis, Idan Shalev, Waylon J. Hastings, Marieke S. Tollenaar, Kieran J. O'Donnell, Megan G. McGill, Irina Pokhvisneva, David T.S. Lin, Julia L. MacIsaac, Michael S. Kobor, Carolina de Weerth, Roseriet Beijers, 2022, Biological Psychology

Telomere shortening and the transition to family caregiving in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study

Nicole D. Armstrong, Marguerite R. Irvin, William E. Haley, Marcela D. Blinka, Debora Kamin Mukaz, Amit Patki, Sue Rutherford Siegel, Idan Shalev, Peter Durda, Rasika A. Mathias, Jeremy D. Walston, David L. Roth, 2022, PLoS One

Obesity and accelerated epigenetic aging in a high-risk cohort of children

Laura Etzel, Waylon Hastings, Molly A. Hall, Christine M. Heim, Michael Meaney, Jennie G. Noll, K O'Donnell, E Rose, Kieran J. O’Donnell, H Schrier, I Pokhvisneva, C Shenk, Emma Rose, Hannah M.C. Schreier, Schreier HMC, I Shalev, Chad E. Shenk, Idan Shalev, 2022, Scientific Reports on p. 8328

Comparing qPCR and DNA methylation-based measurements of telomere length in a high-risk pediatric cohort

Waylon Hastings, Laura Etzel, Christine M. Heim, Jennie Noll, Emma J. Rose, Schreier HMC, Hannah M.C. Schreier, Chad E. Shenk, X Tang, Idan Shalev, 2022, Aging on p. 660-677

Cumulative risk exposure and child cellular aging in a Dutch low-risk community sample

Roseriet Beijers, Ilse ten Thije, Emma Bolhuis, Kieran J. O'Donnell, Marieke S. Tollenaar, Idan Shalev, Waylon J. Hastings, Julia L. MacIsaac, David T.S. Lin, Michael Meaney, Michael S. Kobor, Jay Belsky, Carolina de Weerth, 2022, Psychophysiology

The Flexible Regulation of Emotional Expression Scale for Youth (FREE-Y): Adaptation and Validation Across a Varied Sample of Children and Adolescents

A Haag, C Cha, Jennie G. Noll, D Gee, Chad E. Shenk, Schreier HMC, Hannah M.C. Schreier, Christine M. Heim, Idan Shalev, Emma Rose, A Jorgensen, G Bonanno, 2022, Assessment on p. 10731911221090465

Immune cell dynamics in response to an acute laboratory stressor: a within-person between-group analysis of the biological impact of early life adversity

Laura Etzel, Abner T. Apsley, Brooke C. Mattern, Waylon J. Hastings, Thomas Heller, Nilam Ram, Sue Rutherford Siegel, Idan Shalev, 2022, Stress on p. 347-356

Most-Cited Papers

The p factor: One general psychopathology factor in the structure of psychiatric disorders?

Avshalom Caspi, Renate M. Houts, Daniel W. Belsky, Sidra J. Goldman-Mellor, Honalee Harrington, Salomon Israel, Madeline H. Meier, Sandhya Ramrakha, Idan Shalev, Richie Poulton, Terrie E. Moffitt, 2014, Clinical Psychological Science on p. 119-137

Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: A longitudinal study

I. Shalev, T. E. Moffitt, K. Sugden, B. Williams, R. M. Houts, A. Danese, J. Mill, L. Arseneault, A. Caspi, 2013, Molecular Psychiatry on p. 576-581

Stress and telomere biology: A lifespan perspective

Idan Shalev, Sonja Entringer, Pathik D. Wadhwa, Owen M. Wolkowitz, Eli Puterman, Jue Lin, Elissa S. Epel, 2013, Psychoneuroendocrinology on p. 1835-1842

Childhood exposure to violence and lifelong health: Clinical intervention science and stress-biology research join forces

Terrie E. Moffitt, Louise Arseneault, Andrea Danese, Helen Fisher, Jonathan Mill, Carmine Pariante, Don Baucom, Avshalom Caspi, Edith Chen, Gregory Miller, Kurt Halweg, Ann Katrin Job, Nina Heinrichs, Barbara Heiniger Haldimann, Mariann Grawe-Gerber, Misa Kuper-Yamanaka, Matt Sanders, Idan Shalev, Susanne Walitza, 2013, Development and Psychopathology on p. 1619-1634

Internalizing disorders and leukocyte telomere erosion: A prospective study of depression, generalized anxiety disorder and post-Traumatic stress disorder

I. Shalev, T. E. Moffitt, A. W. Braithwaite, A. Danese, N. I. Fleming, S. Goldman-Mellor, H. L. Harrington, R. M. Houts, S. Israel, R. Poulton, S. P. Robertson, K. Sugden, B. Williams, A. Caspi, 2014, Molecular Psychiatry on p. 1163-1170

Oxytocin receptor and vasopressin receptor 1a genes are respectively associated with emotional and cognitive empathy

F. Uzefovsky, I. Shalev, S. Israel, S. Edelman, Y. Raz, D. Mankuta, A. Knafo-Noam, R. P. Ebstein, 2015, Hormones and Behavior on p. 60-65

Change in the rate of biological aging in response to caloric restriction: Calerie Biobank analysis

Daniel W. Belsky, Kim M. Huffman, Carl F. Pieper, Idan Shalev, William E. Kraus, Rozalyn Anderson, 2018, Journals of Gerontology - Series A Biological Sciences and Medical Sciences on p. 4-10

Microvascular abnormality in schizophrenia as shown by retinal imaging

Madeline H. Meier, Idan Shalev, Terrie E. Moffitt, Shitij Kapur, Richard S.E. Keefe, Tien Y. Wong, Daniel W. Belsky, Hona Lee Harrington, Sean Hogan, Renate Houts, Avshalom Caspi, Richie Poulton, 2013, American Journal of Psychiatry on p. 1451-1459

The association between creativity and 7R polymorphism in the dopamine receptor D4 gene (DRD4)

Naama Mayseless, Florina Uzefovsky, Idan Shalev, Richard P. Ebstein, Simone G. Shamay-Tsoory, 2013, Frontiers in Human Neuroscience

Childhood Sexual Abuse and Early Timing of Puberty

Jennie G. Noll, P Trickett, J Long, S Negriff, E Susman, Idan Shalev, J Li, F Putnam, 2017, Journal of Adolescent Health on p. 65-71