Idan Shalev

Assistant Professor of Biobehavioral Health

Idan Shalev

Research Summary

Interdisciplinary approach to identify mechanisms underpinning the biological embedding of stress across the lifespan with a special focus on biological aging.

Huck Graduate Students

Huck Affiliations

Most Recent Publications

Cross-tissue comparison of telomere length and metrics of DNA integrity, quality, and quantity among individuals aged 8 to 70 years

Sarah Wolf, Waylon Hastings, Qiaofeng Ye, Laura Etzel, Abner Apsley, Christopher Chiaro, Christine Heim, Thomas Heller, Jennie Noll, Hannah Schreier, Chad Shenk, Idan Shalev, PLOS One

Maternal telomere length and oxidative stress in pregnancy: cross-sectional analysis with an exploratory examination of systemic inflammation

Laura Etzel, Qiaofeng Ye, Abner T. Apsley, Chris Chiaro, Lauren E. Petri, John Kozlosky, Cathi Propper, Roger Mills-Koonce, Sarah J. Short, Patricia Garrett-Peters, Idan Shalev, 2025, BMC Pregnancy and Childbirth

Cross-tissue comparison of epigenetic aging clocks in humans

Abner T. Apsley, Qiaofeng Ye, Avshalom Caspi, Christopher Chiaro, Laura Etzel, Waylon J. Hastings, Christine M. Heim, John Kozlosky, Jennie G. Noll, Hannah M.C. Schreier, Chad E. Shenk, Karen Sugden, Idan Shalev, 2025, Aging Cell

A cluster-randomized trial of water, sanitation, handwashing and nutritional interventions on stress and epigenetic programming

Audrie Lin, Andrew N. Mertens, Md Ziaur Rahman, Sophia T. Tan, Dora Il’yasova, Ivan Spasojevic, Shahjahan Ali, Christine P. Stewart, Lia C.H. Fernald, Lisa Kim, Liying Yan, Ann Meyer, Md Rabiul Karim, Sunny Shahriar, Gabrielle Shuman, Benjamin F. Arnold, Alan E. Hubbard, Syeda L. Famida, Salma Akther, Md Saheen Hossen, Palash Mutsuddi, Abul K. Shoab, Idan Shalev, Mahbubur Rahman, Leanne Unicomb, Christopher D. Heaney, Patricia Kariger, John M. Colford, Stephen P. Luby, Douglas A. Granger, 2024, Nature Communications

Parental age at birth, telomere length, and autism spectrum disorders in the UK Biobank cohort

Qiaofeng Ye, Abner T. Apsley, Waylon J. Hastings, Laura Etzel, Craig Newschaffer, Idan Shalev, 2024, Autism Research on p. 2223-2231

Pre-pandemic individual and household predictors of caregiver and child COVID-19-related stress in a high-risk sample

Anneke Olson, C Shenk, Zachary Fisher, Christine Heim, Jennie Noll, Idan Shalev, Hannah Schreier, 2024, Child Protection and Practice on p. 9

Early life adversity is associated with differential gene expression in immune cells: A cluster-based analysis across an acute psychosocial stressor

Laura Etzel, Abner T. Apsley, Waylon J. Hastings, Qiaofeng Ye, Idan Shalev, 2024, Brain, Behavior, and Immunity on p. 724-733

Effect of long-term caloric restriction on telomere length in healthy adults: CALERIE™ 2 trial analysis

Waylon J. Hastings, Qiaofeng Ye, Sarah E. Wolf, Calen P. Ryan, Sai Krupa Das, Kim M. Huffman, Michael S. Kobor, William E. Kraus, Julia L. MacIsaac, Corby K. Martin, Susan B. Racette, Leanne M. Redman, Daniel W. Belsky, Idan Shalev, 2024, Aging Cell

Stress biomarkers and child development in young children in Bangladesh

Zachary Butzin-Dozier, Andrew N. Mertens, Sophia T. Tan, Douglas A. Granger, Helen O. Pitchik, Dora Il'yasova, Fahmida Tofail, Md Ziaur Rahman, Ivan Spasojevic, Idan Shalev, Shahjahan Ali, Mohammed Rabiul Karim, Sunny Shahriar, Syeda Luthfa Famida, Gabrielle Shuman, Abul K. Shoab, Salma Akther, Md Saheen Hossen, Palash Mutsuddi, Mahbubur Rahman, Leanne Unicomb, Kishor K. Das, Liying Yan, Ann Meyer, Christine P. Stewart, Alan E. Hubbard, Ruchira Tabassum Naved, Kausar Parvin, Md Mahfuz Al Mamun, Stephen P. Luby, John M. Colford, Lia C.H. Fernald, Audrie Lin, 2024, Psychoneuroendocrinology

Cross-tissue comparison of telomere length and quality metrics of DNA among individuals aged 8 to 70 years

Sarah E. Wolf, Waylon J. Hastings, Qiaofeng Ye, Laura Etzel, Abner T. Apsley, Christopher Chiaro, Christine C. Heim, Thomas Heller, Jennie G. Noll, Hannah M.C. Schreier, Chad E. Shenk, Idan Shalev, 2024, PLoS One

Most-Cited Papers

Change in the rate of biological aging in response to caloric restriction: Calerie Biobank analysis

Daniel W. Belsky, Kim M. Huffman, Carl F. Pieper, Idan Shalev, William E. Kraus, Rozalyn Anderson, 2018, Journals of Gerontology - Series A Biological Sciences and Medical Sciences on p. 4-10

Oxytocin receptor and vasopressin receptor 1a genes are respectively associated with emotional and cognitive empathy

F. Uzefovsky, I. Shalev, S. Israel, S. Edelman, Y. Raz, D. Mankuta, A. Knafo-Noam, R. P. Ebstein, 2015, Hormones and Behavior on p. 60-65

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

R. Waziry, C. P. Ryan, D. L. Corcoran, K. M. Huffman, M. S. Kobor, M. Kothari, G. H. Graf, V. B. Kraus, W. E. Kraus, D. T.S. Lin, C. F. Pieper, M. E. Ramaker, M. Bhapkar, S. K. Das, L. Ferrucci, W. J. Hastings, M. Kebbe, D. C. Parker, S. B. Racette, I. Shalev, B. Schilling, D. W. Belsky, 2023, Nature Aging

Comparability of biological aging measures in the National Health and Nutrition Examination Study, 1999–2002

Waylon J. Hastings, Idan Shalev, Daniel W. Belsky, 2019, Psychoneuroendocrinology on p. 171-178

Childhood Sexual Abuse and Early Timing of Puberty

Jennie G. Noll, P Trickett, J Long, S Negriff, E Susman, Idan Shalev, J Li, F Putnam, 2017, Journal of Adolescent Health on p. 65-71

Early-life stress and reproductive cost: A two-hit developmental model of accelerated aging?

Idan Shalev, Jay Belsky, 2016, Medical Hypotheses on p. 41-47

Contextual adversity, telomere erosion, pubertal development, and health: Two models of accelerated aging, or one?

Jay Belsky, Idan Shalev, 2016, Development and Psychopathology on p. 1367-1383

Telomere length and chronological age across the human lifespan: A systematic review and meta-analysis of 414 study samples including 743,019 individuals

Qiaofeng Ye, Abner T. Apsley, Laura Etzel, Waylon J. Hastings, John T. Kozlosky, Cade Walker, Sarah E. Wolf, Idan Shalev, 2023, Ageing Research Reviews

Obesity and accelerated epigenetic aging in a high-risk cohort of children

Laura Etzel, Waylon Hastings, Molly A. Hall, Christine M. Heim, Michael Meaney, Jennie G. Noll, K O'Donnell, E Rose, Kieran J. O’Donnell, H Schrier, I Pokhvisneva, C Shenk, Emma Rose, Hannah M.C. Schreier, Schreier HMC, I Shalev, Chad E. Shenk, Idan Shalev, 2022, Scientific Reports on p. 8328

Translating measures of biological aging to test effectiveness of geroprotective interventions: What can we learn from research on telomeres?

Waylon J. Hastings, Idan Shalev, Daniel W. Belsky, 2017, Frontiers in Genetics