Collage for hero banner of microbes

One Health Microbiome Center

As one of the largest and most active organizations in the field, the internationally awarded One Health Microbiome Center has a mission to optimize, accelerate, and disseminate long-lasting applications and knowledge on the microbiome.

Microbiomes are communities of microorganisms (e.g., bacteria, fungi, viruses, archaea, and protozoa) that inhabit an environment, including plants, animals, soils, oceans, and our homes. As we peer into our bodies, half of the cells in a human are microbes, and the gene catalogue of these human-associated microbes dwarfs that of our own human genome by at least 100-fold. Members of the microbiome can range from helpful to harmful, but notably the vast majority do not cause disease. As a collective, microbial assemblages and their genomes have profound impacts on solutions related to agricultural production, human chronic diseases, and ecosystem stability, among others. As we break ground on understanding how these diverse communities impact life, it is clear that the new study of the microbiome is central to biological systems, education, and applications in a rapidly changing world.

The center deeply embodies my vision for growing interdisciplinary excellence

—Penn State President Neeli Bendapudi, November 2024

550

Members

$224M

Awarded Funding

42+

Departments

100

Country Collaborations

9

American Academy of Microbiology Fellows

2000+

Publications in a Five-Year Period

First Ph.D

In Microbiome Science

Pierce Prize

First Ever Awarded to a Center, Not an Individual

News

Chemical engineering professor honored for work on plant-based tissue scaffolds

Amir Sheikhi, the Dorothy Foehr Huck and J. Lloyd Huck Early Career Chair in Biomaterials and Regenerative Engineering and associate professor of chemical engineering at Penn State, recently received the 2025 Early Career Investigator Award from the journal BioResources. The award recognized a paper published by Sheikhi and his research team in 2026, titled “All-Cellulose Cryogels with Tunable Extracellular Matrix-MimeticArchitecture.”

One Health Microbiome Center awards Interdisciplinary Innovation Fellowships

The One Health Microbiome Center (OHMC) of the Huck Institutes of the Life Sciences at Penn State has selected three recipients for the 2026 Interdisciplinary Innovation Fellowship (IIF), a competitive funding opportunity that supports trainee-led projects bringing together diverse disciplines in innovative and impactful ways. This year, three recipients were each awarded funds to advance collaborative research through the development of new skills, tools and approaches that transcend traditional academic boundaries.

Ganda, Kovac and Hao named Huck chairs

A trio of Penn State faculty members have been named Huck chairs by the Huck Institutes of the Life Sciences in recognition of their research endeavors and track records of service to key Huck units.

Fourteen interdisciplinary research teams receive 2026 IEE seed grants

Fourteen interdisciplinary research teams have received funding through the Institute of Energy and the Environment’s (IEE) 2026 Seed Grant Program. The program supports basic and applied research that lays the groundwork to pursue external funding and is guided by IEE’s five strategic research themes. This year, the program awarded seed funding to more than 40 researchers across 10 colleges and campuses and 21 departments and units.