Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology

Claire Thomas

Research Summary

Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Huck Affiliations

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Publication Tags

These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.

Spectrin Proteins Drosophila Annexins Membranes Protein Plasma Endosomes Cell Membrane Synapses Tetramer Multivesicular Bodies Nuclear Membrane Myoblasts Ubiquitin Oligomer Epidermal Growth Factor Receptors Nuclear Envelope Processing Morphogenesis Cell Adhesion Molecules Eye Phenotype Adherens Junctions Proteome

Most Recent Publications

Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion

Rui Duan, Ji Hoon Kim, Khurts Shilagardi, Eric S. Schiffhauer, Donghoon M. Lee, Sungmin Son, Shuo Li, Claire Thomas, Tianzhi Luo, Daniel A. Fletcher, Douglas N. Robinson, Elizabeth H. Chen, 2018, Nature Cell Biology on p. 688-698

Spectrin tetramer formation is not required for viable development in drosophila

Mansi R. Khanna, Floyd J. Mattie, Kristen C. Browder, Megan D. Radyk, Stephanie E. Crilly, Katelyn J. Bakerink, Sandra L. Harper, David W. Speicher, Graham H. Thomas, 2015, Journal of Biological Chemistry on p. 706-715

Cytoplasmic capes are nuclear envelope intrusions that are enriched in endosomal proteins and depend upon β<sub>H</sub>-Spectrin and Annexin B9

Juan Wu, Katelyn J. Bakerink, Meagan E. Evangelista, Graham H. Thomas, 2014, PLoS One

Annexin B9 binds to β<sub>H</sub>-spectrin and is required for multivesicular body function in Drosophila

Monika Tjota, Seung Kyu Lee, Juan Wu, Janice A. Williams, Mansi R. Khanna, Graham H. Thomas, 2011, The Quarterly journal of microscopical science on p. 2914-2926

Rac1 modulation of the apical domain is negatively regulated by β <sub>Heavy</sub>-spectrin

Seung Kyu Lee, Graham H. Thomas, 2011, Cell Differentiation and Development on p. 116-128

Towards a membrane proteome in Drosophila: A method for the isolation of plasma membrane

Mansi R. Khanna, Bruce A. Stanley, Graham H. Thomas, 2010, BMC Genomics

The cell adhesion molecule Roughest depends on ßH<sub>eavy-</sub>spectrin during eye morphogenesis in Drosophila

Hyun Gwan Lee, Daniela Zarnescu, Bryce MacIver, Graham H. Thomas, 2010, The Quarterly journal of microscopical science on p. 277-285

Brush border spectrin is required for early endosome recycling in Drosophila

Matthew D. Phillips, Graham H. Thomas, 2006, The Quarterly journal of microscopical science on p. 1361-1370

The C-terminal domain of Drosophila β<sub>Heavy</sub>-spectrin exhibits autonomous membrane association and modulates membrane area

Janice A. Williams, Bryce MacIver, Elizabeth Klipfell, Graham H. Thomas, 2004, The Quarterly journal of microscopical science on p. 771-782

Conformational compliance of spectrins in membrane deformation, morphogenesis and signaling

Graham Thomas, Discher Dennis, 2003, on p. 213-241

Most-Cited Papers

Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion

Rui Duan, Ji Hoon Kim, Khurts Shilagardi, Eric S. Schiffhauer, Donghoon M. Lee, Sungmin Son, Shuo Li, Claire Thomas, Tianzhi Luo, Daniel A. Fletcher, Douglas N. Robinson, Elizabeth H. Chen, 2018, Nature Cell Biology on p. 688-698

Spectrin tetramer formation is not required for viable development in drosophila

Mansi R. Khanna, Floyd J. Mattie, Kristen C. Browder, Megan D. Radyk, Stephanie E. Crilly, Katelyn J. Bakerink, Sandra L. Harper, David W. Speicher, Graham H. Thomas, 2015, Journal of Biological Chemistry on p. 706-715

Cytoplasmic capes are nuclear envelope intrusions that are enriched in endosomal proteins and depend upon β<sub>H</sub>-Spectrin and Annexin B9

Juan Wu, Katelyn J. Bakerink, Meagan E. Evangelista, Graham H. Thomas, 2014, PLoS One