Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology

Claire Thomas

Research Summary

Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Huck Affiliations

Links

Publication Tags

Spectrin Drosophila Proteins Membranes Annexins Cell Membrane Adherens Junctions Multivesicular Bodies Morphogenesis Endosomes Cell Adhesion Molecules Phenotype Synapses Myoblasts Nuclear Membrane Proteome Nuclear Envelope Epidermal Growth Factor Receptors Ubiquitin Skeleton Processing Cadherins Alleles Membrane Proteins Actins

Most Recent Papers

Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion

Rui Duan, Ji Hoon Kim, Khurts Shilagardi, Eric S. Schiffhauer, Donghoon M. Lee, Sungmin Son, Shuo Li, Claire Thomas, Tianzhi Luo, Daniel A. Fletcher, Douglas N. Robinson, Elizabeth H. Chen, 2018, Nature Cell Biology on p. 688-698

Spectrin tetramer formation is not required for viable development in drosophila

Mansi R. Khanna, Floyd J. Mattie, Kristen C. Browder, Megan D. Radyk, Stephanie E. Crilly, Katelyn J. Bakerink, Sandra L. Harper, David W. Speicher, Graham H. Thomas, 2015, Journal of Biological Chemistry on p. 706-715

Cytoplasmic capes are nuclear envelope intrusions that are enriched in endosomal proteins and depend upon β<sub>H</sub>-Spectrin and Annexin B9

Juan Wu, Katelyn J. Bakerink, Meagan E. Evangelista, Graham H. Thomas, 2014, PloS one

Annexin B9 binds to β<sub>H</sub>-spectrin and is required for multivesicular body function in Drosophila

Monika Tjota, Seung Kyu Lee, Juan Wu, Janice A. Williams, Mansi R. Khanna, Claire Madison Thomas, 2011, Journal of Cell Science on p. 2914-2926

Rac1 modulation of the apical domain is negatively regulated by β Heavy-spectrin

Seung Kyu Lee, Claire Madison Thomas, 2011, Mechanisms of Development on p. 116-128

Towards a membrane proteome in Drosophila

Mansi R. Khanna, Bruce A. Stanley, Graham H. Thomas, 2010, BMC genomics

The cell adhesion molecule Roughest depends on ßH<sub>eavy-</sub>spectrin during eye morphogenesis in Drosophila

Hyun Gwan Lee, Daniela Zarnescu, Bryce MacIver, Claire Madison Thomas, 2010, Journal of Cell Science on p. 277-285

Brush border spectrin is required for early endosome recycling in Drosophila

Matthew D. Phillips, Graham H. Thomas, 2006, Journal of Cell Science on p. 1361-1370

The C-terminal domain of Drosophila β<sub>Heavy</sub>-spectrin exhibits autonomous membrane association and modulates membrane area

Janice A. Williams, Bryce MacIver, Elizabeth Klipfell, Graham H. Thomas, 2004, Journal of Cell Science on p. 771-782

Crumbs interacts with moesin and β<sub>Heavy</sub>-spectrin in the apical membrane skeleton of Drosophila

Emmanuelle Médina, Janice Williams, Elizabeth Klipfell, Daniela Zarnescu, Graham Thomas, André Le Bivic, 2002, Journal of Cell Biology on p. 941-951

Most-Cited Papers

The cell adhesion molecule Roughest depends on ßH<sub>eavy-</sub>spectrin during eye morphogenesis in Drosophila

Hyun Gwan Lee, Daniela Zarnescu, Bryce MacIver, Claire Madison Thomas, 2010, Journal of Cell Science on p. 277-285

Towards a membrane proteome in Drosophila

Mansi R. Khanna, Bruce A. Stanley, Graham H. Thomas, 2010, BMC genomics

Annexin B9 binds to β<sub>H</sub>-spectrin and is required for multivesicular body function in Drosophila

Monika Tjota, Seung Kyu Lee, Juan Wu, Janice A. Williams, Mansi R. Khanna, Claire Madison Thomas, 2011, Journal of Cell Science on p. 2914-2926

Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion

Rui Duan, Ji Hoon Kim, Khurts Shilagardi, Eric S. Schiffhauer, Donghoon M. Lee, Sungmin Son, Shuo Li, Claire Thomas, Tianzhi Luo, Daniel A. Fletcher, Douglas N. Robinson, Elizabeth H. Chen, 2018, Nature Cell Biology on p. 688-698

Rac1 modulation of the apical domain is negatively regulated by β Heavy-spectrin

Seung Kyu Lee, Claire Madison Thomas, 2011, Mechanisms of Development on p. 116-128

Spectrin tetramer formation is not required for viable development in drosophila

Mansi R. Khanna, Floyd J. Mattie, Kristen C. Browder, Megan D. Radyk, Stephanie E. Crilly, Katelyn J. Bakerink, Sandra L. Harper, David W. Speicher, Graham H. Thomas, 2015, Journal of Biological Chemistry on p. 706-715

Cytoplasmic capes are nuclear envelope intrusions that are enriched in endosomal proteins and depend upon β<sub>H</sub>-Spectrin and Annexin B9

Juan Wu, Katelyn J. Bakerink, Meagan E. Evangelista, Graham H. Thomas, 2014, PloS one