Daniel Hayes

Huck Chair in Nanotherapeutics and Regenerative Medicine; Professor of Biomedical Engineering; Director, Center of Excellence in Industrial Biotechnology

Daniel Hayes

Research Summary

Biomaterials engineering for applications ranging from regenerative medicine to lab-on-a-chip technologies. An emphasis on nanomaterials, macromolecules and composite structures. Ongoing efforts include development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, cell encapsulation and delivery materials and hybrid in situ polymerizing grafts/augments.

Huck Affiliations


Publication Tags

Nanoparticles Stem Cells Hydrogels Silver Scaffolds Tissue Bone Oligonucleotides Micrornas Cellulose Hydrogel Polycaprolactone Silver Nanoparticles Osteogenic Genes Tissue Engineering Adipose Tissue Proteomics Nanocomposites Regenerative Medicine Microrna Gene Expression Modulation Skin Chemical Analysis

Most Recent Papers

Hybrid adipose graft materials synthesized from chemically modified adipose extracellular matrix

Shue Li, Yiming Liu, Jacob McCann, Dino J. Ravnic, Jeffrey M. Gimble, Daniel J. Hayes, 2022, Journal of Biomedical Materials Research - Part A on p. 156-163

MiRNA induced co-differentiation and cross-talk of adipose tissue-derived progenitor cells for 3D heterotypic pre-vascularized bone formation

Nazmiye Celik, Myoung Hwan Kim, Daniel J. Hayes, Ibrahim T. Ozbolat, 2021, Biofabrication

Breast Cancer Reconstruction: Design Criteria for a Humanized Microphysiological System

Trivia Frazier, Christopher Williams, Michael Henderson, Tamika Duplessis, Emma Rogers, Xiying Wu, Katie Hamel, Elizabeth C. Martin, Omair Mohiuddin, Shahensha Shaik, Ram Devireddy, Brian G. Rowan, Daniel J. Hayes, Jeffrey M. Gimble, 2021, Tissue Engineering - Part A. on p. 479-488

MicroRNA sequencing of CD34+ sorted adipose stem cells undergoing endotheliogenesis

Shahensha Shaik, Elizabeth Martin, Daniel Hayes, Jeffrey Gimble, Ram Devireddy, 2021, Stem Cells and Development on p. 265-288

Clinical translational potential in skin wound regeneration for adipose‐derived, blood‐derived, and cellulose materials: Cells, exosomes, and hydrogels

Trivia Frazier, Andrea Alarcon, Xiying Wu, Omair A. Mohiuddin, Jessica M. Motherwell, Anders H. Carlsson, Robert J. Christy, Judson V. Edwards, Robert T. Mackin, Nicolette Prevost, Elena Gloster, Qiang Zhang, Guangdi Wang, Daniel J. Hayes, Jeffrey M. Gimble, 2020, Biomolecules on p. 1-21

Characterization and Proteomic Analysis of Decellularized Adipose Tissue Hydrogels Derived from Lean and Overweight/Obese Human Donors

Omair A. Mohiuddin, Jessica M. Motherwell, Emma Rogers, Melyssa R. Bratton, Qiang Zhang, Guangdi Wang, Bruce Bunnell, Daniel J. Hayes, Jeffrey M. Gimble, 2020, Advanced Biology

Photocontrolled miR-148b nanoparticles cause apoptosis, inflammation and regression of Ras induced epidermal squamous cell carcinomas in mice

Yiming Liu, Jacob T. Bailey, Mohammad Abu-Laban, Shue Li, Cong Chen, Adam B. Glick, Daniel J. Hayes, 2020, Biomaterials

Alternating magnetic field mediated release of fluorophores from magnetic nanoparticles by hysteretic heating

Jonathan S. Casey, Julien H. Arrizabalaga, Mohammad Abu-Laban, Jeffrey C. Becca, Benjamin J. Rose, Kevin T. Strickland, Jacob B. Bursavich, Jacob S. McCann, Carlos N. Pacheco, Lasse Jessen, Anilchandra Attaluri, Daniel J. Hayes, 2020, Journal of Colloid and Interface Science on p. 348-355

Differentiation of Adipose Tissue-Derived CD34+/CD31-Cells into Endothelial Cells In Vitro

Anoosha Forghani, Koduru, Srinivas, V, Cong Chen, Ashley Leberfinger, Dino Ravnic, Daniel Hayes, 2020, REGENERATIVE ENGINEERING AND TRANSLATIONAL MEDICINE on p. 101-110

Decellularized Adipose Tissue

Omair A. Mohiuddin, Brett Campbell, J. Nicholas Poche, Caasy Thomas-Porch, Daniel A. Hayes, Bruce A. Bunnell, Jeffrey M. Gimble, 2020, on p. 57-70

Most-Cited Papers

Electrospun bio-nanocomposite scaffolds for bone tissue engineering by cellulose nanocrystals reinforcing maleic anhydride grafted PLA

Chengjun Zhou, Qingfeng Shi, Weihong Guo, Lekeith Terrell, Ammar T. Qureshi, Daniel J. Hayes, Qinglin Wu, 2013, ACS applied materials & interfaces on p. 3847-3854

Silver nanoscale antisense drug delivery system for photoactivated gene silencing

Paige K. Brown, Ammar T. Qureshi, Alyson N. Moll, Daniel J. Hayes, W. Todd Monroe, 2013, ACS Nano on p. 2948-2959

MiR-148b-Nanoparticle conjugates for light mediated osteogenesis ofhuman adipose stromal/stem cells

Ammar T. Qureshi, William T. Monroe, Vinod Dasa, Jeffrey M. Gimble, Daniel J. Hayes, 2013, Biomaterials on p. 7799-7810

Human adipose-derived stem cells and three-dimensional scaffold constructs

Andrea S. Zanetti, Cristina Sabliov, Jeffrey M. Gimble, Daniel J. Hayes, 2013, Journal of Biomedical Materials Research - Part B Applied Biomaterials on p. 187-199

Thermoreversible and Injectable ABC Polypeptoid Hydrogels

Sunting Xuan, Chang Uk Lee, Cong Chen, Andrew B. Doyle, Yueheng Zhang, Li Guo, Vijay T. John, Daniel Hayes, Donghui Zhang, 2016, Chemistry of Materials on p. 727-737

A planar microfluidic mixer based on logarithmic spirals

Thomas Scherr, Christian Quitadamo, Preston Tesvich, Daniel Sang Won Park, Terrence Tiersch, Daniel Hayes, Jin Woo Choi, Krishnaswamy Nandakumar, W. Todd Monroe, 2012, Journal of Micromechanics and Microengineering

Photoactivated miR-148b-nanoparticle conjugates improve closure of critical size mouse calvarial defects

Ammar T. Qureshi, Andrew Doyle, Cong Chen, Diana Coulon, Vinod Dasa, Fabio DelPiero, Benjamin Levi, W. Todd Monroe, Jeffrey M. Gimble, Daniel J. Hayes, 2015, Acta Biomaterialia on p. 166-173

Evaluation of bone regeneration potential of dental follicle stem cells for treatment of craniofacial defects

Maryam Rezai-Rad, Jonathan F. Bova, Mahdi Orooji, Jennifer Pepping, Ammar Qureshi, Fabio Del Piero, Daniel Hayes, Shaomian Yao, 2015, Cytotherapy on p. 1572-1581

A novel composite film for detection and molecular weight determination of organic vapors

Bishnu P. Regmi, Joshua Monk, Bilal El-Zahab, Susmita Das, Francisco R. Hung, Daniel J. Hayes, Isiah M. Warner, 2012, Journal of Materials Chemistry on p. 13732-13741

Targeting Calcium Magnesium Silicates for Polycaprolactone/Ceramic Composite Scaffolds

Cong Chen, Pilanda Watkins-Curry, Mollie Smoak, Katie Hogan, Steve Deese, Gregory T. McCandless, Julia Y. Chan, Daniel J. Hayes, 2015, ACS Biomaterials Science and Engineering on p. 94-102