People: Cellular Developmental Biology

Sarah Ades

Associate Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.

Charles Anderson

Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.

Sarah Assmann

Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.

Michael Axtell

Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets

Lu Bai

Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.

Craig Cameron

Berg Professor of Biochemistry and Molecular Biology; Eberly Chair in Biochemistry and Molecular Biology
Defining the molecular details of genome replication in positive-strand RNA viruses and identifying components of this process suitable for antiviral drug development.

Margherita Cantorna

Emphasis Area Representative, Immunology and Infectious Disease; Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology
The research in the Cantorna lab seeks to understand the working of the immune system. Animal models of several human diseases including enteric infections and inflammatory bowel disease are utilized to determine the cellular targets and molecular signals by which dietary components regulate immunity. Areas of expertise: Host resistance to infection; immune-mediated diseases; multiple sclerosis; inflammatory bowel disease; T cells; gastrointestinal microbiota; gnotobiotics; vitamins A & D regulation of immune function; edible mushrooms; and selenium.

Douglas Cavener

Professor and Verne M. Willaman Dean, Eberly College of Science; Chair of the Genetics Program
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Gong Chen

Professor and Verne M. Willaman Chair in Life Sciences
Developing innovative technologies for brain repair using newly established in vivo cell conversion technology.

Daniel Cosgrove

Eberly Chair and Professor of Biology
Mechanism of plant growth. Function and evolution of expansins. Biochemistry and rheology of plant cell walls. Growth responses to light, hormones, and water stress and other stimuli.

Francisco Diaz

Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Patrick Drew

Huck Distinguished Associate Professor of Neural Engineering and Neurosurgery
Control and development of the cerebral blood flow, neurovascular coupling.

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Santhosh Girirajan

Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.

Ying Gu

Associate Professor, Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

William Hancock

Professor of Bioengineering
The detailed workings of motor proteins and their role in intracellular transport and cell motility.

Wendy Hanna-Rose

Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Timothy Jegla

Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.

Kenneth Keiler

Professor of Biochemistry and Molecular Biology
Small RNAs and protein localization in bacterial development and antimicrobial drug discovery.

Zhi-Chun Lai

Professor of Biology, Biochemistry and Molecular Biology; Emphasis Area Representative, Cell and Developmental Biology
Signal Transduction, Growth Control, and Cancer Genetics

Tae-Hee Lee

Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin

Xiaojun Lian

Assistant Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.

Scott Lindner

Assistant Professor of Biochemistry & Molecular Biology
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Aimin Liu

Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.

Bernhard Luscher

Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Costas Maranas

Donald B. Broughton Professor of Chemical Engineering
Computational studies of metabolism and gene regulation.

Timothy Meredith

Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.

Gustavo Nader

Associate Professor of Kinesiology
Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Curtis Omiecinski

Professor of Veterinary & Biomedical Sciences; H. Thomas and Dorothy Willits Hallowell Chair; Emphasis Area Representative, Molecular Toxicology
Nuclear receptor biology and genomics. Xenobiotic Receptor systems that regulate biotransformation, detoxication, cancer predisposition, lipid and energy homeostasis.

Richard Ordway

Professor of Molecular Neuroscience and Genetics
Genetic analysis of neural function.

Robert Paulson

Professor of Veterinary and Biomedical Sciences; Emphasis Area Representative, Genetics
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress

Franklin Pugh

Director of the Center for Eukaryotic Gene Regulation; Willaman Professor in Molecular Biology
Biochemistry and genomics of eukaryotic transcription regulation.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Melissa Rolls

Chair, Intercollege Graduate Degree Program in Molecular, Cellular and Integrative Biosciences; Director of the Center for Cellular Dynamics; Professor of Biochemistry and Molecular Biology
Subcellular compartmentalization of neurons. The cellular basis of neuronal polarity and neuronal responses to injury including degeneration and regeneration.

Lorraine Santy

Associate Professor of Biochemistry and Molecular Biology
The signals and processes that initiate migration in epithelial cells.

Anthony Schmitt

Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.

Song Tan

Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.

Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Na Xiong

Associate Professor, Department of Veterinary and Biomedical Science
Development and function of gamma/delta T cells, a class of immune cells with various roles in microbial immunity, inflammation regulation and tumor surveillance.

Jian Yang

Professor of Bioengineering
Development of new biodegradable polymers for use in engineering elastic tissues such as blood vessel, tendon, ligament, and cardiac tissue, and in other applications such as biological labeling, bioimaging and drug delivery.

Siyang Zheng

Associate Professor of Bioengineering
My laboratory aims at developing and applying micro/nano technologies for biological and medical applications. On one hand, I am interested in studying miniaturized devices and systems that can be integrated with biological system in vitro and in vivo. On the other hand, I am eager to apply these technologies for fundamental biological research, clinic diagnosis and treatment. The research is highly multidisciplinary, interfacing at engineering, biological sciences, physical sciences, and medicine.