People: Cellular Developmental Biology
Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.
Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.
Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets
Berg Professor of Biochemistry and Molecular Biology; Eberly Chair in Biochemistry and Molecular Biology
Defining the molecular details of genome replication in positive-strand RNA viruses and identifying components of this process suitable for antiviral drug development.
Emphasis Area Representative, Immunology and Infectious Disease; Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor in Molecular Immunology
The research in the Cantorna lab seeks to understand the working of the immune system. Animal models of several human diseases including enteric infections and inflammatory bowel disease are utilized to determine the cellular targets and molecular signals by which dietary components regulate immunity. Areas of expertise: Host resistance to infection; immune-mediated diseases; multiple sclerosis; inflammatory bowel disease; T cells; gastrointestinal microbiota; gnotobiotics; vitamins A & D regulation of immune function; edible mushrooms; and selenium.
Professor and Verne M. Willaman Dean, Eberly College of Science; Chair of the Genetics Program
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.
Eberly Chair and Professor of Biology
Mechanism of plant growth. Function and evolution of expansins. Biochemistry and rheology of plant cell walls. Growth responses to light, hormones, and water stress and other stimuli.
Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action
Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.
Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.
Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.
Professor of Veterinary & Biomedical Sciences; H. Thomas and Dorothy Willits Hallowell Chair; Emphasis Area Representative, Molecular Toxicology
Nuclear receptor biology and genomics. Xenobiotic Receptor systems that regulate biotransformation, detoxication, cancer predisposition, lipid and energy homeostasis.
Professor of Veterinary and Biomedical Sciences; Emphasis Area Representative, Genetics
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress
Chair, Intercollege Graduate Degree Program in Molecular, Cellular and Integrative Biosciences; Director of the Center for Cellular Dynamics; Professor of Biochemistry and Molecular Biology
Subcellular compartmentalization of neurons. The cellular basis of neuronal polarity and neuronal responses to injury including degeneration and regeneration.
Associate Professor of Biochemistry and Molecular Biology
Epithelial cells form barriers that divide different compartments in the body. These cells are normally stationary but become migratory during processes such as the repair of tissue damage or the metastasis of epithelial tumors. The Santy lab is interested in understanding the signals and processes that initiate migration in epithelial cells.
Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.
Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.
Associate Professor, Department of Veterinary and Biomedical Science
Development and function of gamma/delta T cells, a class of immune cells with various roles in microbial immunity, inflammation regulation and tumor surveillance.
Professor of Bioengineering
Development of new biodegradable polymers for use in engineering elastic tissues such as blood vessel, tendon, ligament, and cardiac tissue, and in other applications such as biological labeling, bioimaging and drug delivery.
Associate Professor of Bioengineering
My laboratory aims at developing and applying micro/nano technologies for biological and medical applications. On one hand, I am interested in studying miniaturized devices and systems that can be integrated with biological system in vitro and in vivo. On the other hand, I am eager to apply these technologies for fundamental biological research, clinic diagnosis and treatment. The research is highly multidisciplinary, interfacing at engineering, biological sciences, physical sciences, and medicine.