Margherita Cantorna

Director of the Center for Molecular Immunology and Infectious Disease; Distinguished Professor of Molecular Immunology

Margherita Cantorna

Research Summary

Understanding the working of the immune system. Utilizing animal models of several human diseases including enteric infections and inflammatory bowel disease to determine the cellular targets and molecular signals by which dietary components regulate immunity.

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Vitamin D Calcitriol Receptors Vitamin A T Lymphocytes Citrobacter Rodentium Infection Infections Inflammation Colon Small Intestine Microbiota Homeostasis Genes Vitamin A Deficiency Mice Vitamin Vitamin D Deficiency T Cells Lymphocytes Gene Expression Knockout Mice Inflammatory Bowel Diseases Colitis Epithelial Cells Cells

Most Recent Publications

Margherita T. Cantorna, Juhi Arora, 2023, Journal of Steroid Biochemistry and Molecular Biology

Mark B. Meyer, Carlos Bernal-Mizrachi, Daniel D. Bikle, Madhu Biyani, Moray J. Campbell, Snehal N. Chaudhari, Sylvia Christakos, Sue A. Ingles, Megan M. Knuth, Seong Min Lee, Thomas S. Lisse, Eva S. Liu, Isabelle Piec, Lori A. Plum, Sudhaker D. Rao, Carmen J. Reynolds, Tom D. Thacher, John H. White, Margherita T. Cantorna, 2023, Journal of Steroid Biochemistry and Molecular Biology

Vitamin D, microbiota, and inflammatory bowel disease

Margherita T. Cantorna, Juhi Arora, 2023, on p. 1057-1073

Adrian R. Martineau, Margherita T. Cantorna, 2022, Nature Reviews Immunology on p. 529-530

Micha L. Davila, Ming Xu, Chengyu Huang, Erin R. Gaddes, Levi Winter, Margherita T. Cantorna, Yong Wang, Na Xiong, 2022, iScience

Juhi Arora, Jinpeng Wang, Veronika Weaver, Yongwei Zhang, Margherita T. Cantorna, 2022, Journal of Steroid Biochemistry and Molecular Biology

Zhi Chai, Yafei Lyu, Qiuyan Chen, Cheng Hsin Wei, I.M. Snyder, Lindsay M. Snyder, Veronika Weaver, Aswathy Sebastian, István Albert, Qunhua Li, Margherita T. Cantorna, Catharine Ross, A Ross, 2022, Nutrients on p. 1563

Juhi Arora, Devanshi Patel, McKayla Nicol, Cassandra Field, Katherine Restori, Jinpeng Wang, Nicole Froelich, Bhuvana Katkere, Josey Terwilliger, Veronika Weaver, others, Erin Luley, Kathleen Kelly, Girish S. Kirimanjeswara, Troy Sutton, Margherita T. Cantorna, 2022, Nutrients on p. 3061

Zhi Chai, Yafei Lyu, Qiuyan Chen, Cheng Hsin Wei, Lindsay M. Snyder, Veronika Weaver, Aswathy Sebastian, István Albert, Qunhua Li, Margherita T. Cantorna, A. Catharine Ross, 2021, Nutrition Reports International

Lindsay M. Snyder, Juhi Arora, Mary J. Kennett, Veronika Weaver, Margherita T. Cantorna, 2020, Frontiers in Immunology

Most-Cited Papers

Margherita T. Cantorna, Lindsay Snyder, Yang Ding Lin, Linlin Yang, 2015, Nutrients on p. 3011-3021

Margherita T. Cantorna, Lindsay Snyder, Juhi Arora, 2019, Critical Reviews in Biochemistry and Molecular Biology on p. 184-192

Mary Jo Feeney, Johanna Dwyer, Clare M. Hasler-Lewis, John A. Milner, Manny Noakes, Sylvia Rowe, Mark Wach, Robert B. Beelman, Joe Caldwell, Margherita T. Cantorna, Lisa A. Castlebury, Shu Ting Chang, Lawrence J. Cheskin, Roger Clemens, Greg Drescher, Victor L. Fulgoni, David B. Haytowitz, Van S. Hubbard, David Law, Amy Myrdal Miller, Bart Minor, Susan S. Percival, Gabriela Riscuta, Barbara Schneeman, Suzanne Thornsbury, Cheryl D. Toner, Catherine E. Woteki, Dayong Wu, 2014, Journal of Nutrition

Margherita T. Cantorna, Kaitlin McDaniel, Stephanie Bora, Jing Chen, Jamaal James, 2014, Experimental Biology and Medicine on p. 1524-1530

Naveen Kaushal, Avinash K. Kudva, Andrew D. Patterson, Christopher Chiaro, Mary J. Kennett, Dhimant Desai, Shantu Amin, Bradley A. Carlson, Margherita T. Cantorna, K. Sandeep Prabhu, 2014, Journal of Immunology on p. 3683-3692

The vitamin D receptor turns off chronically activated T cells

Margherita T. Cantorna, Amanda Waddell, 2014, Annals of the New York Academy of Sciences on p. 70-75

Stephanie A. Bora, Mary J. Kennett, Philip B. Smith, Andrew D. Patterson, Margherita T. Cantorna, 2018, Frontiers in Immunology

Yang Ding Lin, Juhi Arora, Kevin Diehl, Stephanie A. Bora, Margherita T. Cantorna, 2019, Frontiers in Immunology

News Articles Featuring Margherita Cantorna

22 Best Vitamin D-Rich Foods for Immunity & Bone Health

Give your health a boost during the winter months with these foods rich in vitamin D

How Vitamin D Can Affect Your Gut Microbiome

Getting daily sunlight is good for your mind — and your microbiome.

7 Things to know before taking Vitamin D Supplements

Known as the "sunshine pill” for its supposed ability to mimic the effects of sunshine on health, vitamin D supplements are a billion-dollar industry. People take vitamin D supplements for a variety of reasons, mental and physical. Some take it if they feel sad, perhaps as the result of the winter blues, for example. Others take it because vitamin D supposedly plays a role in bone health.

Why getting enough vitamin D in wintertime is so important

Winter is upon us and so is the risk of vitamin D deficiency and infections. Vitamin D — which is made in our skin following sunlight exposure and also found in oily fish (mackerel, tuna and sardines), mushrooms and fortified dairy and nondairy substitutes — is essential for good health.

Why you need more Vitamin D in the winter

Winter is upon us and so is the risk of vitamin D deficiency and infections. Vitamin D, which is made in our skin following sunlight exposure and also found in oily fish (mackerel, tuna and sardines), mushrooms and fortified dairy and nondairy substitutes, is essential for good health.

Why you need more Vitamin D in the winter

Winter is upon us and so is the risk of vitamin D deficiency and infections. Vitamin D, which is made in our skin following sunlight exposure and also found in oily fish (mackerel, tuna and sardines), mushrooms and fortified dairy and nondairy substitutes, is essential for good health.

Science on Tap Explores Mushrooms, Their Genes, and Our Health

Nearly two-thirds of white-button mushrooms consumed in the United States come from Pennsylvania, according to the U.S. Department of Agriculture, and this month's Science on Tap will bring together a pair of Penn State researchers to share their insight into the popular fungus.

Eating white button mushrooms may improve blood sugar control

A new study has found that eating white button mushrooms can affect glucose, or blood sugar, regulation, thereby reducing diabetes and other metabolic conditions, such as obesity.