William Hancock

Professor of Bioengineering

William Hancock

Research Summary

The detailed workings of motor proteins and their role in intracellular transport and cell motility.

Huck Affiliations

Publication Tags

These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.

Kinesin Microtubules Dyneins Adenosine Triphosphate Hydrolysis Force Neck Head Velocity Aptitude Kinetics Tubulin Nucleotides In Vitro Techniques Length Polymerization Dynactin Complex Fluorescence Proteins Population Molecules Spindle Apparatus Polymerization Reaction Phosphates Direction Compound

Most Recent Publications

Simulations suggest robust microtubule attachment of kinesin and dynein in antagonistic pairs

Tzu Chen Ma, Allison M. Gicking, Qingzhou Feng, William O. Hancock, 2023, Biophysical Journal on p. 3299-3313

Kinesin-1, -2 and -3 use family-specific mechanochemical strategies to effectively compete with dynein during bidirectional transport

Allison M. Gicking, Tzu Chen Ma, Qingzhou Feng, Rui Jiang, Somaye Badieyan, Michael A. Cianfrocco, William O. Hancock, 2023, Biophysical Journal on p. 411a

Serapion Pyrpassopoulos, Allison M. Gicking, Taylor M. Zaniewski, William O. Hancock, E. Michael Ostap, 2023, Proceedings of the National Academy of Sciences of the United States of America

High-Resolution Tracking of Dynein-Dynactin-BicD2 Complexes

Qingzhou Feng, Allison M. Gicking, William O. Hancock, 2023, on p. 177-186

Manipulation of Force Geometry using Optical Tweezers Reveals Novel Features of Biomolecular Interactions

Serapion Pyrpassopoulos, Allison M. Gicking, Taylor M. Zaniewsky, Henry Shuman, William Hancock, E. Michael Ostap, 2023,

A Solon, T Zaniewski, Patrick O’Brien, P O'Brien, M Clasby, William Hancock, R Ohi, 2022, Molecular Biology of the Cell on p. ar132

William Hancock, 2022, Current Biology on p. R914-R916

P Wisanpitayakorn, K Mickolajczyk, William Hancock, L Vidali, E Tüzel, 2022, Biophysical Journal on p. 1813-1822

Most-Cited Papers

William O. Hancock, 2014, Nature Reviews Molecular Cell Biology on p. 615-628

Johan O.L. Andreasson, Bojan Milic, Geng Yuan Chen, Nicholas R. Guydosh, William O. Hancock, Steven M. Block, 2015, eLife on p. 1-44

Bojan Milic, Johan O.L. Andreasson, William O. Hancock, Steven M. Block, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 14136-14140

Keith J. Mickolajczyk, Nathan C. Deffenbaugh, Jaime Ortega Arroyo, Joanna Andrecka, Philipp Kukura, William O. Hancock, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. E7186-E7193

Yalei Chen, William O. Hancock, 2015, Nature Communications

Göker Arpaʇ, Shankar Shastry, William O. Hancock, Erkan Tüzel, 2014, Biophysical Journal on p. 1896-1904

William O. Hancock, 2016, Biophysical Journal on p. 1216-1225

Johan O.L. Andreasson, Shankar Shastry, William O. Hancock, Steven M. Block, 2015, Current Biology on p. 1166-1175

Gregory J. Hoeprich, Andrew R. Thompson, Derrick P. McVicker, William O. Hancock, Christopher L. Berger, 2014, Biophysical Journal on p. 1691-1700

Hugo Arellano-Santoyo, Elisabeth A. Geyer, Ema Stokasimov, Geng Yuan Chen, Xiaolei Su, William Hancock, Luke M. Rice, David Pellman, 2017, Developmental Cell on p. 37-51.e8