Francisco Diaz
Director of the Center for Reproductive Health and Biology; Associate Professor of Reproductive Biology
-
206 Henning
University Park, PA - fjd10@psu.edu
- 814-865-1499
Research Summary
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.
Huck Graduate Students
Huck Affiliations
- Integrative and Biomedical Physiology
- Molecular, Cellular, and Integrative Biosciences
- Center for Reproductive Biology and Health
- One Health Microbiome Center
Links
Most Recent Publications
Ovarian Production of Estradiol: The Two-Cell, Two-Gonadotropin Model
Francisco Diaz, Allison Carothers, 2025, on p. 8
Synergistic enhancement of the mouse Pramex1 and Pramel1 in repressing retinoic acid (RA) signaling during gametogenesis
M Yang, Francisco Diaz, Krause ART, Ana Rita T. Krause, Yuguo Lei, Wan Sheng Liu, 2024, Cell and Bioscience on p. 28
Role of Zinc Insufficiency in Bovine Granulosa Cell Viability
Allison Carothers, Francisco Diaz, 2024,
Inhibition of mouse oocyte maturation by a specific IK1 inhibitor
Francisco Diaz, 2023,
Inhibition of mouse oocyte maturation by a specific IK1 inhibitor
Ana Krause, Tyler Garner, Francisco Diaz, 2023,
Hormonal Regulation and Zinc Influx Activity of Zrt- and Irt-like Protein 9 (ZIP9) in the Mammalian Ovary.
Francisco Diaz, 2023,
Ad libitum feeding alters mRNA abundance in the ovarian cortex of broiler breeder hens
Kate Anthony, Tyler Garner, Ramesh Ramachandran, Francisco Javier Diaz, F Diaz, 2022, Reproduction and Fertility on p. 110-121
The PRAMEY protein in sperm function during in vitro fertilization (IVF).
Francisco Diaz, 2022,
A reconfigurable microfluidic building block platform for high-throughput nonhormonal contraceptive screening
Jyong-Huei Lee, Carl Van Der Linden, Francisco Diaz, Pak Kin Wong, 2022, Lab on a Chip - Miniaturisation for Chemistry and Biology on p. 2531--2539
Menstrual Cycle-Associated Changes in Micronutrient Biomarkers Concentration: A Prospective Cohort Study
Sixtus Aguree, Laura E. Murray-Kolb, Francisco Diaz, Alison Gernand, 2022, Journal of the American Nutrition Association on p. 339--348
Most-Cited Papers
Role of zinc in female reproduction
Tyler Bruce Garner, James Malcolm Hester, Allison Carothers, Francisco J. Diaz, 2021, Biology of Reproduction on p. 976-994
Age-related accumulation of de novo mitochondrial mutations in mammalian oocytes and somatic tissues
Barbara Arbeithuber, James Hester, Marzia A. Cremona, Nicholas Stoler, Arslan Zaidi, Bonnie Higgins, Kate Anthony, Francesca Chiaromonte, Francisco J. Diaz, Kateryna D. Makova, 2020, PLoS Biology
Lats1 deletion causes increased germ cell apoptosis and follicular cysts in mouse ovaries
Tianyanxin Sun, Melissa Pepling, Francisco J. Diaz, 2015, Biology of Reproduction on p. 22--1
Ovulatory signals alter granulosa cell behavior through YAP1 signaling
Tianyanxin Sun, Francisco J. Diaz, 2019, Reproductive Biology and Endocrinology
Advanced age increases frequencies of de novo mitochondrial mutations in macaque oocytes and somatic tissues
Barbara Arbeithuber, Mazia Cremona, James Hester, Alison Barrett, Bonnie Higgins, Kate Anthony, Francesca Chiaromonte, Francisco J. Diaz, Kateryna Makova, 2022, Proceedings of the National Academy of Sciences of the United States of America on p. e2118740119
Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression
James Hester, Wendy Hanna-Rose, Francisco Diaz, 2017, Comparative Biochemistry and Physiology - C Toxicology and Pharmacology on p. 203-209
A novel testis-specific protein, PRAMEY, is involved in spermatogenesis in cattle
Wan Sheng Liu, Yaqi Zhao, Chen Lu, Gang Ning, Yun Ma, Francisco Diaz, Michael O'Connor, 2017, Reproduction on p. 847-863
A Multiwell Microfluidic Device for Analyzing and Screening Nonhormonal Contraceptive Agents
Hui Li, Tyler Garner, Francisco Diaz, Pak Wong, 2019, Small
Deletion of the mouse X-linked Prame gene causes germ cell reduction in spermatogenesis
Chen Lu, Mingyao Yang, Randall M. Rossi, Aihua Wang, Weber B. Feitosa, Francisco J. Diaz, Wan Sheng Liu, 2020, Molecular Reproduction and Development on p. 666-679
Transition Metal Chelator Induces Progesterone Production in Mouse Cumulus-Oocyte Complexes and Corpora Lutea
X. Tian, K. Anthony, Francisco J. Diaz, 2017, Biological Trace Element Research on p. 374-383
News Articles Featuring Francisco Diaz
Jan 24, 2025
Biologists Rip Trump’s 'Non-Sensical' Executive Order Declaring Only 2 Sexes
One of President Donald Trump’s first official acts on Monday was signing an executive order declaring there are only two sexes.
Full Article
Dec 07, 2023
USDA grant supports reproductive microbiome training program
The USDA NIFA has awarded Penn State a five-year, US$238,500 grant to establish a graduate training pipeline in reproductive microbiome research
Full Article
Dec 06, 2023
New USDA grant to support graduate reproductive microbiome training program
The USDA NIFA has awarded Penn State a five-year, $238,500 grant to establish a graduate training pipeline in reproductive microbiome research.
Full Article
Jun 15, 2023
Animal scientist receives USDA grant to study reproductive dysfunction in cattle
A Penn State animal scientist has received a $650,000 grant from the U.S. Department of Agriculture to lead a team conducting research on reproductive dysfunction in cattle.
Full Article