Francisco Diaz

Director of the Center for Reproductive Health and Biology; Associate Professor of Reproductive Biology

Francisco Diaz

Research Summary

Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Huck Graduate Students

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Publication Tags

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Oocytes Zinc Mitochondrial Dna Proteins Mutation Germ Cells Microfluidics Genes Antigens Messenger Rna Spermatogenesis Fluorescence Mutagenesis Tissue Pedigree Cumulus Cells Mutation Rate Tissues Neoplasms Screening Corpus Luteum Testis Contraceptive Agents Swine Reproduction

Most Recent Publications

Menstrual Cycle-Associated Changes in Micronutrient Biomarkers Concentration: A Prospective Cohort Study

Sixtus Aguree, Laura E. Murray-Kolb, Francisco Diaz, Alison Gernand, 2022, Journal of the American Nutrition Association on p. 339--348

Ad libitum feeding alters mRNA abundance in the ovarian cortex of broiler breeder hens

Kate Anthony, Tyler Garner, Ramesh Ramachandran, Francisco Javier Diaz, F Diaz, 2022, Reproduction and Fertility on p. 110-121

Role of the bovine PRAMEY protein in sperm function during in vitro fertilization (IVF)

Chandlar Kern, Weiwei Wu, Chen Lu, Jianbin Zhang, Yaqi Zhao, Olga Ocon-Grove, Peter Sutovsky, Francisco Diaz, Wan Sheng Liu, 2022, Cell and Tissue Research on p. 577--594

A reconfigurable microfluidic building block platform for high-throughput nonhormonal contraceptive screening

Jyong-Huei Lee, Carl Van Der Linden, Francisco Diaz, Pak Kin Wong, 2022, Lab on a Chip - Miniaturisation for Chemistry and Biology on p. 2531--2539

Advanced age increases frequencies of de novo mitochondrial mutations in macaque oocytes and somatic tissues

Barbara Arbeithuber, Mazia Cremona, James Hester, Alison Barrett, Bonnie Higgins, Kate Anthony, Francesca Chiaromonte, Francisco J. Diaz, Kateryna Makova, 2022, Proceedings of the National Academy of Sciences of the United States of America on p. e2118740119

Role of zinc in female reproduction

Tyler Bruce Garner, James Malcolm Hester, Allison Carothers, Francisco J. Diaz, 2021, Biology of Reproduction on p. 976-994

A Reconfigurable Microfluidic Building Block Platform for High-Throughput Nonhormonal Contraceptive Screening

Jyong Huei Lee, Carl Van Der Linden, Francisco J. Diaz, Pak Kin Wong, 2021, on p. 72-75

Age-related accumulation of de novo mitochondrial mutations in mammalian oocytes and somatic tissues

Barbara Arbeithuber, James Hester, Marzia A. Cremona, Nicholas Stoler, Arslan Zaidi, Bonnie Higgins, Kate Anthony, Francesca Chiaromonte, Francisco J. Diaz, Kateryna D. Makova, 2020, PLoS Biology

Deletion of the mouse X-linked Prame gene causes germ cell reduction in spermatogenesis

Chen Lu, Mingyao Yang, Randall M. Rossi, Aihua Wang, Weber B. Feitosa, Francisco J. Diaz, Wan Sheng Liu, 2020, Molecular Reproduction and Development on p. 666-679

Duplex sequencing uncovers age-related increase in the frequency of de novo indels in mouse mitochondrial DNA.

E Torres-Gonzalez, B Arbeithuber, James Hester, M Cremona, N Stoler, B Higgins, K Anthony, F Chiaromonte, Francisco Diaz, K Makova, 2020,

Most-Cited Papers

Acute dietary zinc deficiency before conception compromises oocyte epigenetic programming and disrupts embryonic development

X. Tian, F. J. Diaz, 2013, Developmental Biology on p. 51-61

Preconception zinc deficiency disrupts postimplantation fetal and placental development in mice

Xi Tian, Kate Anthony, Thomas Neuberger, Francisco J. Diaz, 2014, Biology of Reproduction on p. 1-12

Gonadotropin-releasing hormone, estradiol, and inhibin regulation of follicle-stimulating hormone and luteinizing hormone surges: Implications for follicle emergence and selection in heifers

James M. Haughian, O. J. Ginther, Francisco J. Diaz, Milo C. Wiltbank, 2013, Biology of Reproduction

Oocyte-cumulus cell interactions regulate free intracellular zinc in mouse oocytes

R. S. Lisle, K. Anthony, M. A. Randall, F. J. Diaz, 2013, Reproduction on p. 381-390

Age-related accumulation of de novo mitochondrial mutations in mammalian oocytes and somatic tissues

Barbara Arbeithuber, James Hester, Marzia A. Cremona, Nicholas Stoler, Arslan Zaidi, Bonnie Higgins, Kate Anthony, Francesca Chiaromonte, Francisco J. Diaz, Kateryna D. Makova, 2020, PLoS Biology

Lats1 deletion causes increased germ cell apoptosis and follicular cysts in mouse ovaries

Tianyanxin Sun, Melissa Pepling, Francisco J. Diaz, 2015, Biology of Reproduction on p. 22--1

Prostaglandin F2α Regulation of mRNA for activating protein 1 transcriptional factors in porcine corpora lutea (CL): Lack of induction of JUN and JUND in CL without luteolytic capacity

F. J. Diaz, W. Luo, M. C. Wiltbank, 2013, Domestic Animal Endocrinology on p. 98-108

Differential Expression of PRAMEL1, a Cancer/Testis Antigen, during Spermatogenesis in the Mouse

Bhavesh V. Mistry, Yaqi Zhao, Ti Cheng Chang, Hiroshi Yasue, Mitsuru Chiba, Jon Oatley, Francisco Diaz, Wan Sheng Liu, 2013, PLoS One on p. e60611

Ovulatory signals alter granulosa cell behavior through YAP1 signaling

Tianyanxin Sun, Francisco J. Diaz, 2019, Reproductive Biology and Endocrinology

Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression

James Hester, Wendy Hanna-Rose, Francisco Diaz, 2017, Comparative Biochemistry and Physiology - C Toxicology and Pharmacology on p. 203-209