Patrick Drew

Associate Director of the Neuroscience Institute; Huck Distinguished Associate Professor of Neural Engineering and Neurosurgery

Patrick Drew

Research Summary

Role of blood flow and cerebrospinal fluid movement in the development of neurodegenerative diseases, control of cerebral blood flow, neurovascular coupling.

Huck Affiliations

Links

Publication Tags

Hemodynamics Locomotion Brain Cerebral Blood Volume Photons Dilatation Cerebrovascular Circulation Blood Imaging Techniques Blood Vessels Constriction Oxygen Respiration Infection Bone Oxygenation Cerebrospinal Fluid Sudden Death Epilepsy Calcitonin Gene Related Peptide Radon Malaria Somatosensory Cortex Lasers Vibrissae

Most Recent Papers

Cerebral oxygenation during locomotion is modulated by respiration

Qingguang Zhang, Morgane Roche, Kyle W. Gheres, Emmanuelle Chaigneau, Ravi T. Kedarasetti, William D. Haselden, Serge Charpak, Patrick J. Drew, 2019, Nature communications

Twitches, Blinks, and Fidgets

Patrick James Drew, Aaron T. Winder, Qingguang Zhang, 2019, Neuroscientist on p. 298-313

Anatomical basis and physiological role of cerebrospinal fluid transport through the murine cribriform plate

Jordan N. Norwood, Qingguang Zhang, David Card, Amanda Craine, Timothy M. Ryan, Patrick J. Drew, 2019, eLife

Weak correlations between hemodynamic signals and ongoing neural activity during the resting state

Aaron T. Winder, Christina Echagarruga, Qingguang Zhang, Patrick J. Drew, 2017, Nature Neuroscience on p. 1761-1769

A Murine Model to Study Epilepsy and SUDEP Induced by Malaria Infection

Paddy Ssentongo, Anna E. Robuccio, Godfrey Thuku, Derek G. Sim, Ali Nabi, Fatemeh Bahari, Balaji Shanmugasundaram, Myles W. Billard, Andrew Geronimo, Kurt W. Short, Patrick J. Drew, Jennifer Baccon, Steven L. Weinstein, Frank G. Gilliam, José A. Stoute, Vernon M. Chinchilli, Andrew F. Read, Bruce J. Gluckman, Steven J. Schiff, 2017, Scientific reports

Effects of voluntary locomotion and calcitonin gene-related peptide on the dynamics of single dural vessels in awake mice

Yu Rong Gao, Patrick J. Drew, 2016, Journal of Neuroscience on p. 2503-2516

Mechanical restriction of intracortical vessel dilation by brain tissue sculpts the hemodynamic response

Yu Rong Gao, Stephanie E. Greene, Patrick J. Drew, 2015, NeuroImage on p. 162-176

Quantitative separation of arterial and venous cerebral blood volume increases during voluntary locomotion

Bing Xing Huo, Yu Rong Gao, Patrick J. Drew, 2015, NeuroImage on p. 369-379

Venous cerebral blood volume increase during voluntary locomotion reflects cardiovascular changes

Bing Xing Huo, Stephanie E. Greene, Patrick J. Drew, 2015, NeuroImage on p. 301-312

Determination of vessel cross-sectional area by thresholding in Radon space

Yu Rong Gao, Patrick J. Drew, 2014, Journal of Cerebral Blood Flow and Metabolism on p. 1180-1187

Most-Cited Papers

Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity

Patrick J. Drew, Andy Y. Shih, David Kleinfeld, 2011, Proceedings of the National Academy of Sciences of the United States of America on p. 8473-8478

A polished and reinforced thinned-skull window for long-term imaging of the mouse brain.

Andy Y. Shih, Celine Mateo, Patrick James Drew, Philbert S. Tsai, David Kleinfeld, 2012, Journal of visualized experiments : JoVE

Weak correlations between hemodynamic signals and ongoing neural activity during the resting state

Aaron T. Winder, Christina Echagarruga, Qingguang Zhang, Patrick J. Drew, 2017, Nature Neuroscience on p. 1761-1769

Quantitative separation of arterial and venous cerebral blood volume increases during voluntary locomotion

Bing Xing Huo, Yu Rong Gao, Patrick J. Drew, 2015, NeuroImage on p. 369-379

Mechanical restriction of intracortical vessel dilation by brain tissue sculpts the hemodynamic response

Yu Rong Gao, Stephanie E. Greene, Patrick J. Drew, 2015, NeuroImage on p. 162-176

Determination of vessel cross-sectional area by thresholding in Radon space

Yu Rong Gao, Patrick J. Drew, 2014, Journal of Cerebral Blood Flow and Metabolism on p. 1180-1187

Effects of voluntary locomotion and calcitonin gene-related peptide on the dynamics of single dural vessels in awake mice

Yu Rong Gao, Patrick J. Drew, 2016, Journal of Neuroscience on p. 2503-2516

Venous cerebral blood volume increase during voluntary locomotion reflects cardiovascular changes

Bing Xing Huo, Stephanie E. Greene, Patrick J. Drew, 2015, NeuroImage on p. 301-312

Two-photon imaging of blood flow in the rat cortex

Jonathan D. Driscoll, Andy Y. Shih, Patrick J. Drew, Gert Cauwenberghs, David Kleinfeld, 2013, Cold Spring Harbor Protocols on p. 759-767

A Murine Model to Study Epilepsy and SUDEP Induced by Malaria Infection

Paddy Ssentongo, Anna E. Robuccio, Godfrey Thuku, Derek G. Sim, Ali Nabi, Fatemeh Bahari, Balaji Shanmugasundaram, Myles W. Billard, Andrew Geronimo, Kurt W. Short, Patrick J. Drew, Jennifer Baccon, Steven L. Weinstein, Frank G. Gilliam, José A. Stoute, Vernon M. Chinchilli, Andrew F. Read, Bruce J. Gluckman, Steven J. Schiff, 2017, Scientific reports