Wendy Hanna-Rose
Professor of Biochemistry and Molecular Biology; Head of BMB

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Huck Life Sciences
University Park, - She/Her
- wxh21@psu.edu
- 814-865-7904
Research Summary
Molecular Genetics of Metabolism and Development in C. elegans
Huck Affiliations
Links
Publication Tags
Nad Acoustics Caenorhabditis Elegans Niacinamide Neurons Uridine Monophosphate Ligases Microfluidics Glass Zinc Quinolinic Acid Animals Biosynthesis Metabolic Microchannels Metabolomics Nicotinamide Necrosis Agonist Reactive Ion Etching Epithelial Cells Uridine Glycolysis Molds OogenesisMost Recent Papers
Noncanonical necrosis in 2 different cell types in a Caenorhabditis elegans NAD1 salvage pathway mutant
Rifath N. Reza, Nicholas D. Serra, Ariana C. Detwiler, Wendy Hanna-Rose, Matt Crook, 2022, G3: Genes, Genomes, Genetics
The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans
Eillen Tecle, Crystal B. Chhan, Latisha Franklin, Ryan S. Underwood, Wendy Hanna-Rose, Emily R. Troemel, 2021, PLoS Pathogens
Overactive EGF signaling promotes uv1 cell survival <i>via</i> increased phosphatidylcholine levels and suppression of SBP-1.
M Crook, Wendy Hanna-Rose, 2020, microPublication biology
Animal Model Contributions to Congenital Metabolic Disease
Corinna A. Moro, Wendy Hanna-Rose, 2020, on p. 225-244
Uridine monophosphate synthetase enables eukaryotic de novo NAD<sup>+</sup> biosynthesis from quinolinic acid
Melanie R. McReynolds, Wenqing Wang, Lauren M. Holleran, Wendy Hanna-Rose, 2017, Journal of Biological Chemistry on p. 11147-11153
Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression
James Hester, Wendy Hanna-Rose, Francisco Diaz, 2017, Comparative Biochemistry and Physiology - C Toxicology and Pharmacology on p. 203-209
Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel
Awani Upadhyay, Aditya Pisupati, Timothy Jegla, Matt Crook, Keith J. Mickolajczyk, Matthew Shorey, Laura E. Rohan, Katherine A. Billings, Melissa M. Rolls, William O. Hancock, Wendy Hanna-Rose, 2016, Nature Communications
Acoustofluidics
Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang, 2016, Small on p. 5230
Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures
Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang, 2016, Small on p. 5120-5125
Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression.
J Hester, Wendy Hanna-Rose, F Diaz, 2016, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP on p. 203-209
Most-Cited Papers
Rotational manipulation of single cells and organisms using acoustic waves
Daniel Ahmed, Adem Ozcelik, Nagagireesh Bojanala, Nitesh Nama, Awani Upadhyay, Yuchao Chen, Wendy Hanna-Rose, Tony Jun Huang, 2016, Nature Communications
Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures
Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang, 2016, Small on p. 5120-5125
Morphogenesis of the vulva and the vulval-uterine connection.
Bhagwati P. Gupta, Wendy Hanna-Rose, Paul W. Sternberg, 2012, WormBook : the online review of C. elegans biology on p. 1-20
Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel
Awani Upadhyay, Aditya Pisupati, Timothy Jegla, Matt Crook, Keith J. Mickolajczyk, Matthew Shorey, Laura E. Rohan, Katherine A. Billings, Melissa M. Rolls, William O. Hancock, Wendy Hanna-Rose, 2016, Nature Communications
A postmitotic function and distinct localization mechanism for centralspindlin at a stable intercellular bridge
Kang Zhou, Melissa M. Rolls, Wendy Hanna-Rose, 2013, Developmental Biology on p. 13-22
Comparative metabolomic profiling reveals that dysregulated glycolysis stemming from lack of salvage NAD<sup>+</sup> biosynthesis impairs reproductive development in Caenorhabditis elegans
Wenqing Wang, Melanie R. McReynolds, Jimmy F. Goncalves, Muya Shu, Ineke Dhondt, Bart P. Braeckman, Stephanie E. Lange, Kelvin Kho, Ariana C. Detwiler, Marisa J. Pacella, Wendy Hanna-Rose, 2015, Journal of Biological Chemistry on p. 26163-26179
Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression
James Hester, Wendy Hanna-Rose, Francisco Diaz, 2017, Comparative Biochemistry and Physiology - C Toxicology and Pharmacology on p. 203-209
Uridine monophosphate synthetase enables eukaryotic de novo NAD<sup>+</sup> biosynthesis from quinolinic acid
Melanie R. McReynolds, Wenqing Wang, Lauren M. Holleran, Wendy Hanna-Rose, 2017, Journal of Biological Chemistry on p. 11147-11153
Acoustofluidics
Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang, 2016, Small on p. 5230
Necrosis in C. elegans
Matt Crook, Avni Upadhyay, Wendy Hanna-Rose, 2013, on p. 171-182