Wendy Hanna-Rose
Professor of Biochemistry and Molecular Biology; Head of BMB

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Huck Life Sciences
University Park, - She/Her
- wxh21@psu.edu
- 814-865-7904
Research Summary
Molecular Genetics of Metabolism and Development in C. elegans
Huck Affiliations
Links
Publication Tags
Nad Epithelial Cells Niacinamide Caenorhabditis Elegans Acoustics Zinc Ligases Quinolinic Acid Uridine Monophosphate Metabolic Animals Nucleosides Metabolomics Fertility Pathogens Infections Biosynthesis Phosphorylase Purines Infection Purine Nucleoside Phosphorylase Nicotinamide Neurons Microfluidics DisorderMost Recent Publications
Erratum: The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans (PLoS Pathogens (2021) 17:4 (e1009350) DOI: 10.1371/journal.ppat.1009350)
Eillen Tecle, Crystal B. Chhan, Latisha Franklin, Ryan S. Underwood, Wendy Hanna-Rose, Emily R. Troemel, 2022, PLoS Pathogens
Noncanonical necrosis in 2 different cell types in a Caenorhabditis elegans NAD1 salvage pathway mutant
Rifath N. Reza, Nicholas D. Serra, Ariana C. Detwiler, Wendy Hanna-Rose, Matt Crook, 2022, G3: Genes, Genomes, Genetics
The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans
Eillen Tecle, Crystal B. Chhan, Latisha Franklin, Ryan S. Underwood, Wendy Hanna-Rose, Emily R. Troemel, 2021, PLoS Pathogens
Overactive EGF signaling promotes uv1 cell survival <i>via</i> increased phosphatidylcholine levels and suppression of SBP-1.
M Crook, Wendy Hanna-Rose, 2020, microPublication biology
Animal Model Contributions to Congenital Metabolic Disease
Corinna A. Moro, Wendy Hanna-Rose, 2020, on p. 225-244
Nicotinamide Inhibits Aphid Fecundity and Impacts Survival
Sampurna Sattar, M Martinez, A Ruiz, Wendy Hanna-Rose, G Thompson, 2019, Scientific Reports on p. 19709
Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression
James Hester, Wendy Hanna-Rose, Francisco Diaz, 2017, Comparative Biochemistry and Physiology - C Toxicology and Pharmacology on p. 203-209
Uridine monophosphate synthetase enables eukaryotic de novo NAD<sup>+</sup> biosynthesis from quinolinic acid
Melanie R. McReynolds, Wenqing Wang, Lauren M. Holleran, Wendy Hanna-Rose, 2017, Journal of Biological Chemistry on p. 11147-11153
Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel
Awani Upadhyay, Aditya Pisupati, Timothy Jegla, Matt Crook, Keith J. Mickolajczyk, Matthew Shorey, Laura E. Rohan, Katherine A. Billings, Melissa M. Rolls, William O. Hancock, Wendy Hanna-Rose, 2016, Nature Communications
Acoustofluidics: Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures (Small 37/2016)
Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang, 2016, Small on p. 5230
Most-Cited Papers
Rotational manipulation of single cells and organisms using acoustic waves
Daniel Ahmed, Adem Ozcelik, Nagagireesh Bojanala, Nitesh Nama, Awani Upadhyay, Yuchao Chen, Wendy Hanna-Rose, Tony Jun Huang, 2016, Nature Communications
Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures
Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang, 2016, Small on p. 5120-5125
Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel
Awani Upadhyay, Aditya Pisupati, Timothy Jegla, Matt Crook, Keith J. Mickolajczyk, Matthew Shorey, Laura E. Rohan, Katherine A. Billings, Melissa M. Rolls, William O. Hancock, Wendy Hanna-Rose, 2016, Nature Communications
A postmitotic function and distinct localization mechanism for centralspindlin at a stable intercellular bridge
Kang Zhou, Melissa M. Rolls, Wendy Hanna-Rose, 2013, Developmental Biology on p. 13-22
Comparative metabolomic profiling reveals that dysregulated glycolysis stemming from lack of salvage NAD<sup>+</sup> biosynthesis impairs reproductive development in Caenorhabditis elegans
Wenqing Wang, Melanie R. McReynolds, Jimmy F. Goncalves, Muya Shu, Ineke Dhondt, Bart P. Braeckman, Stephanie E. Lange, Kelvin Kho, Ariana C. Detwiler, Marisa J. Pacella, Wendy Hanna-Rose, 2015, Journal of Biological Chemistry on p. 26163-26179
Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression
James Hester, Wendy Hanna-Rose, Francisco Diaz, 2017, Comparative Biochemistry and Physiology - C Toxicology and Pharmacology on p. 203-209
Uridine monophosphate synthetase enables eukaryotic de novo NAD<sup>+</sup> biosynthesis from quinolinic acid
Melanie R. McReynolds, Wenqing Wang, Lauren M. Holleran, Wendy Hanna-Rose, 2017, Journal of Biological Chemistry on p. 11147-11153
Acoustofluidics: Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures (Small 37/2016)
Adem Ozcelik, Nitesh Nama, Po Hsun Huang, Murat Kaynak, Melanie R. McReynolds, Wendy Hanna-Rose, Tony Jun Huang, 2016, Small on p. 5230
The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans
Eillen Tecle, Crystal B. Chhan, Latisha Franklin, Ryan S. Underwood, Wendy Hanna-Rose, Emily R. Troemel, 2021, PLoS Pathogens
Animal Model Contributions to Congenital Metabolic Disease
Corinna A. Moro, Wendy Hanna-Rose, 2020, on p. 225-244
News Articles Featuring Wendy Hanna-Rose
Nov 09, 2022
Schlegels endow Early Career Professorship in biochemistry and molecular biology
Retired Pen State faculty Robert “Bob” and Peggy Schlegel couldn’t afford to hire a cleaning service and caterer every time a new faculty job candidate came to town.
Full Article