Wendy Hanna-Rose

Professor of Biochemistry and Molecular Biology; Head of BMB

Wendy Hanna-Rose

Research Summary

Molecular Genetics of Metabolism and Development in C. elegans

Huck Affiliations

Links

Publication Tags

Nad Caenorhabditis Elegans Niacinamide Acoustics Uridine Monophosphate Glycolysis Biosynthesis Ligases Metabolomics Quinolinic Acid Zinc Biosynthetic Pathways Cell Survival Enzymes Cells Medicine Colloids Physics Pathology Salvaging Phosphatidylcholines Manipulators Optical Character Recognition Fertility Muscles

Most Recent Papers

Uridine monophosphate synthetase enables eukaryotic de novo NAD<sup>+</sup> biosynthesis from quinolinic acid

Melanie R. McReynolds, Wenqing Wang, Lauren M. Holleran, Wendy Hanna-Rose, 2017, Journal of Biological Chemistry on p. 11147-11153

Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression

James Hester, Wendy Hanna-Rose, Francisco Diaz, 2017, Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology on p. 203-209

Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel

Awani Upadhyay, Aditya Pisupati, Timothy Jegla, Matt Crook, Keith J. Mickolajczyk, Matthew Shorey, Laura E. Rohan, Katherine A. Billings, Melissa M. Rolls, William O. Hancock, Wendy Hanna-Rose, 2016, Nature communications

Rotational manipulation of single cells and organisms using acoustic waves

Daniel Ahmed, Adem Ozcelik, Nagagireesh Bojanala, Nitesh Nama, Awani Upadhyay, Yuchao Chen, Wendy Hanna-Rose, Tony Jun Huang, 2016, Nature communications

Epidermal growth factor receptor cell survival signaling requires phosphatidylcholine biosynthesis

Matt Crook, Awani Upadhyay, Liyana J. Ido, Wendy Hanna-Rose, 2016, G3: Genes, Genomes, Genetics on p. 3533-3540

Comparative metabolomic profiling reveals that dysregulated glycolysis stemming from lack of salvage NAD<sup>+</sup> biosynthesis impairs reproductive development in Caenorhabditis elegans

Wenqing Wang, Melanie R. McReynolds, Jimmy F. Goncalves, Muya Shu, Ineke Dhondt, Bart P. Braeckman, Stephanie E. Lange, Kelvin Kho, Ariana C. Detwiler, Marisa J. Pacella, Wendy Hanna-Rose, 2015, Journal of Biological Chemistry on p. 26163-26179

An NAD<sup>+</sup> biosynthetic pathway enzyme functions cell non-autonomously in C. elegans development

Matt Crook, Melanie R. Mcreynolds, Wenqing Wang, Wendy Hanna-Rose, 2014, Developmental Dynamics on p. 965-976

A postmitotic function and distinct localization mechanism for centralspindlin at a stable intercellular bridge

Kang Zhou, Melissa M. Rolls, Wendy Hanna-Rose, 2013, Developmental biology on p. 13-22

Muscle type-specific responses to NAD+ salvage biosynthesis promote muscle function in Caenorhabditis elegans

Tracy L. Vrablik, Wenqing Wang, Awani Upadhyay, Wendy Hanna-Rose, 2011, Developmental biology on p. 387-394

SUN-1 and ZYG-12, mediators of centrosome-nucleus attachment, are a functional SUN/KASH pair in Caenorhabditis elegans

I. L. Minn, Melissa M. Rolls, Wendy Hanna-Rose, Christian J. Malone, 2009, Molecular biology of the cell on p. 4586-4595

Most-Cited Papers

Rotational manipulation of single cells and organisms using acoustic waves

Daniel Ahmed, Adem Ozcelik, Nagagireesh Bojanala, Nitesh Nama, Awani Upadhyay, Yuchao Chen, Wendy Hanna-Rose, Tony Jun Huang, 2016, Nature communications

A postmitotic function and distinct localization mechanism for centralspindlin at a stable intercellular bridge

Kang Zhou, Melissa M. Rolls, Wendy Hanna-Rose, 2013, Developmental biology on p. 13-22

Comparative metabolomic profiling reveals that dysregulated glycolysis stemming from lack of salvage NAD<sup>+</sup> biosynthesis impairs reproductive development in Caenorhabditis elegans

Wenqing Wang, Melanie R. McReynolds, Jimmy F. Goncalves, Muya Shu, Ineke Dhondt, Bart P. Braeckman, Stephanie E. Lange, Kelvin Kho, Ariana C. Detwiler, Marisa J. Pacella, Wendy Hanna-Rose, 2015, Journal of Biological Chemistry on p. 26163-26179

Muscle type-specific responses to NAD+ salvage biosynthesis promote muscle function in Caenorhabditis elegans

Tracy L. Vrablik, Wenqing Wang, Awani Upadhyay, Wendy Hanna-Rose, 2011, Developmental biology on p. 387-394

Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel

Awani Upadhyay, Aditya Pisupati, Timothy Jegla, Matt Crook, Keith J. Mickolajczyk, Matthew Shorey, Laura E. Rohan, Katherine A. Billings, Melissa M. Rolls, William O. Hancock, Wendy Hanna-Rose, 2016, Nature communications

Uridine monophosphate synthetase enables eukaryotic de novo NAD<sup>+</sup> biosynthesis from quinolinic acid

Melanie R. McReynolds, Wenqing Wang, Lauren M. Holleran, Wendy Hanna-Rose, 2017, Journal of Biological Chemistry on p. 11147-11153

An NAD<sup>+</sup> biosynthetic pathway enzyme functions cell non-autonomously in C. elegans development

Matt Crook, Melanie R. Mcreynolds, Wenqing Wang, Wendy Hanna-Rose, 2014, Developmental Dynamics on p. 965-976

Zinc deficiency reduces fertility in C. elegans hermaphrodites and disrupts oogenesis and meiotic progression

James Hester, Wendy Hanna-Rose, Francisco Diaz, 2017, Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology on p. 203-209

Epidermal growth factor receptor cell survival signaling requires phosphatidylcholine biosynthesis

Matt Crook, Awani Upadhyay, Liyana J. Ido, Wendy Hanna-Rose, 2016, G3: Genes, Genomes, Genetics on p. 3533-3540