Lu Bai
Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
-
206B Huck Life Sciences
University Park, PA - lub15@psu.edu
- 814-863-4824
Research Summary
Single cell / single molecule study of chromatin and gene regulation.
Huck Affiliations
Publication Tags
Genes Gene Expression Nucleosomes Transcription Factors Cells Yeasts Saccharomycetales Yeast Endonucleases Phosphoric Monoester Hydrolases Noise Genome Chromatin Dna Directed Rna Polymerases Dna Fluorescence Microscopy Cell Cycle Prediction Compensation And Redress Promoter Regions Transcription Stem Cells Kinetics Gene ProteinsMost Recent Papers
Existence, Transition, and Propagation of Intermediate Silencing States in Ribosomal DNA
Fan Zou, Manyu Du, Hengye Chen, Lu Bai, 2019, Molecular and cellular biology
Enhancement of LacI binding in vivo
Manyu Du, Seth Kodner, Lu Bai, 2019, Nucleic acids research on p. 9609-9618
Dissociation rate compensation mechanism for budding yeast pioneer transcription factors
Benjamin T. Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G. Poirier, 2019, eLife
Using time-lapse fluorescence microscopy to study gene regulation
Fan Zou, Lu Bai, 2019, Methods
Three distinct mechanisms of long-distance modulation of gene expression in yeast
Manyu Du, Qian Zhang, Lu Bai, 2017, PLoS genetics
Interallelic interaction and gene regulation In budding yeast
Daoyong Zhang, Lu Bai, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 4428-4433
Regulation of cell-to-cell variability in divergent gene expression
Chao Yan, Shuyang Wu, Christopher Pocetti, Lu Bai, 2016, Nature communications
The rts1 regulatory subunit of PP2A phosphatase controls expression of the ho endonuclease via localization of the Ace2 transcription factor
Emily J. Parnell, Yaxin Yu, Rafael Lucena, Youngdae Yoon, Lu Bai, Douglas R. Kellogg, David J. Stillman, 2014, Journal of Biological Chemistry on p. 35431-35437
Transcription under torsion
Jie Ma, Lu Bai, Michelle D. Wang, 2013, Science on p. 1580-1583
Multiple Sequence-Specific Factors Generate the Nucleosome-Depleted Region on CLN2 Promoter
Lu Bai, Andrej Ondracka, Frederick R. Cross, 2011, Molecular cell on p. 465-476
Most-Cited Papers
Transcription under torsion
Jie Ma, Lu Bai, Michelle D. Wang, 2013, Science on p. 1580-1583
Synergistic action of RNA polymerases in overcoming the nucleosomal barrier
Jing Jin, Lu Bai, Daniel S. Johnson, Robert M. Fulbright, Maria L. Kireeva, Mikhail Kashlev, Michelle D. Wang, 2010, Nature Structural and Molecular Biology on p. 745-752
Multiple Sequence-Specific Factors Generate the Nucleosome-Depleted Region on CLN2 Promoter
Lu Bai, Andrej Ondracka, Frederick R. Cross, 2011, Molecular cell on p. 465-476
Interallelic interaction and gene regulation In budding yeast
Daoyong Zhang, Lu Bai, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 4428-4433
Regulation of cell-to-cell variability in divergent gene expression
Chao Yan, Shuyang Wu, Christopher Pocetti, Lu Bai, 2016, Nature communications
Comparison of pause predictions of two sequence-dependent transcription models
Lu Bai, Michelle D. Wang, 2010, Journal of Statistical Mechanics: Theory and Experiment
Three distinct mechanisms of long-distance modulation of gene expression in yeast
Manyu Du, Qian Zhang, Lu Bai, 2017, PLoS genetics
The rts1 regulatory subunit of PP2A phosphatase controls expression of the ho endonuclease via localization of the Ace2 transcription factor
Emily J. Parnell, Yaxin Yu, Rafael Lucena, Youngdae Yoon, Lu Bai, Douglas R. Kellogg, David J. Stillman, 2014, Journal of Biological Chemistry on p. 35431-35437
Dissociation rate compensation mechanism for budding yeast pioneer transcription factors
Benjamin T. Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G. Poirier, 2019, eLife
Chromatin
Nicolas E. Buchler, Lu Bai, 2011, Current Biology