Lu Bai

Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics

Lu Bai

Research Summary

Single cell / single molecule study of chromatin and gene regulation.

Huck Affiliations

Publication Tags

Genes Gene Expression Nucleosomes Transcription Factors Cells Yeasts Saccharomycetales Yeast Endonucleases Phosphoric Monoester Hydrolases Noise Genome Chromatin Dna Directed Rna Polymerases Dna Fluorescence Microscopy Cell Cycle Prediction Compensation And Redress Promoter Regions Transcription Stem Cells Kinetics Gene Proteins

Most Recent Papers

Existence, Transition, and Propagation of Intermediate Silencing States in Ribosomal DNA

Fan Zou, Manyu Du, Hengye Chen, Lu Bai, 2019, Molecular and cellular biology

Enhancement of LacI binding in vivo

Manyu Du, Seth Kodner, Lu Bai, 2019, Nucleic acids research on p. 9609-9618

Dissociation rate compensation mechanism for budding yeast pioneer transcription factors

Benjamin T. Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G. Poirier, 2019, eLife

Using time-lapse fluorescence microscopy to study gene regulation

Fan Zou, Lu Bai, 2019, Methods

Three distinct mechanisms of long-distance modulation of gene expression in yeast

Manyu Du, Qian Zhang, Lu Bai, 2017, PLoS genetics

Interallelic interaction and gene regulation In budding yeast

Daoyong Zhang, Lu Bai, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 4428-4433

Regulation of cell-to-cell variability in divergent gene expression

Chao Yan, Shuyang Wu, Christopher Pocetti, Lu Bai, 2016, Nature communications

The rts1 regulatory subunit of PP2A phosphatase controls expression of the ho endonuclease via localization of the Ace2 transcription factor

Emily J. Parnell, Yaxin Yu, Rafael Lucena, Youngdae Yoon, Lu Bai, Douglas R. Kellogg, David J. Stillman, 2014, Journal of Biological Chemistry on p. 35431-35437

Transcription under torsion

Jie Ma, Lu Bai, Michelle D. Wang, 2013, Science on p. 1580-1583

Multiple Sequence-Specific Factors Generate the Nucleosome-Depleted Region on CLN2 Promoter

Lu Bai, Andrej Ondracka, Frederick R. Cross, 2011, Molecular cell on p. 465-476

Most-Cited Papers

Transcription under torsion

Jie Ma, Lu Bai, Michelle D. Wang, 2013, Science on p. 1580-1583

Synergistic action of RNA polymerases in overcoming the nucleosomal barrier

Jing Jin, Lu Bai, Daniel S. Johnson, Robert M. Fulbright, Maria L. Kireeva, Mikhail Kashlev, Michelle D. Wang, 2010, Nature Structural and Molecular Biology on p. 745-752

Multiple Sequence-Specific Factors Generate the Nucleosome-Depleted Region on CLN2 Promoter

Lu Bai, Andrej Ondracka, Frederick R. Cross, 2011, Molecular cell on p. 465-476

Interallelic interaction and gene regulation In budding yeast

Daoyong Zhang, Lu Bai, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 4428-4433

Regulation of cell-to-cell variability in divergent gene expression

Chao Yan, Shuyang Wu, Christopher Pocetti, Lu Bai, 2016, Nature communications

Comparison of pause predictions of two sequence-dependent transcription models

Lu Bai, Michelle D. Wang, 2010, Journal of Statistical Mechanics: Theory and Experiment

Three distinct mechanisms of long-distance modulation of gene expression in yeast

Manyu Du, Qian Zhang, Lu Bai, 2017, PLoS genetics

The rts1 regulatory subunit of PP2A phosphatase controls expression of the ho endonuclease via localization of the Ace2 transcription factor

Emily J. Parnell, Yaxin Yu, Rafael Lucena, Youngdae Yoon, Lu Bai, Douglas R. Kellogg, David J. Stillman, 2014, Journal of Biological Chemistry on p. 35431-35437

Dissociation rate compensation mechanism for budding yeast pioneer transcription factors

Benjamin T. Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G. Poirier, 2019, eLife

Chromatin

Nicolas E. Buchler, Lu Bai, 2011, Current Biology