Lu Bai

Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics

Lu Bai

Research Summary

Single cell / single molecule study of chromatin and gene regulation.

Huck Graduate Students

Huck Affiliations

Publication Tags

These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.

Nucleosomes Genes Genome Gene Expression Yeasts Yeast Thermodynamics Saccharomycetales Transcription Factors Cells Saccharomyces Cerevisiae Chromatin Fluorescence Proteins Chromosomes Promoter Regions Modeling Memory Activins Human Embryonic Stem Cells Noise Cell Positioning Origin Recognition Complex Dna

Most Recent Publications

Predicting Nucleosome Positioning Using Statistical Equilibrium Models

H Kharerin, Lu Bai, 2023, Star Protocol on p. 101926

Nucleosome-directed replication origin licensing independent of a consensus DNA sequence

Sai Li, Michael R. Wasserman, Olga Yurieva, Lu Bai, Michael E. O’Donnell, Shixin Liu, 2022, Nature Communications

Chemically Induced Chromosomal Interaction (CICI) method to study chromosome dynamics and its biological roles

Manyu Du, Fan Zou, Yi Li, Yujie Yan, Lu Bai, 2022, Nature Communications

Origin recognition complex harbors an intrinsic nucleosome remodeling activity

Sai Li, Michael R. Wasserman, Olga Yurieva, Lu Bai, Michael E. O’Donnell, Shixin Liu, 2022, Proceedings of the National Academy of Sciences of the United States of America

Mechanisms underlying WNT-mediated priming of human embryonic stem cells

Anna Yoney, Lu Bai, Ali H. Brivanlou, Eric D. Siggia, 2022, Journal of Embryology and Experimental Morphology

Mechanisms underlying WNT-mediated priming of human embryonic stem cells

Anna Yoney, Lu Bai, Ali H. Brivanlou, Eric D. Siggia, 2022, Journal of Embryology and Experimental Morphology

Partitioned usage of chromatin remodelers by nucleosome-displacing factors

Hengye Chen, Hungyo Kharerin, Archana Dhasarathy, Michael Kladde, Lu Bai, 2022, Cell Reports

Chemically-induced chromosomal interactions (CICI) method to perturb chromosomal conformation and study its functions

Manyu Du, Fan Zou, Yi Li, Yujie Yan, Lu Bai, 2022, Nature Communication on p. 757

Thermodynamic modeling of genome-wide nucleosome depleted regions in yeast

Hungyo Kharerin, Lu Bai, 2021, PLoS Computational Biology

Ash1 and Tup1 dependent repression of the Saccharomyces cerevisiae HO promoter requires activator-dependent nucleosome eviction

Emily J. Parnell, Timothy J. Parnell, Chao Yan, Lu Bai, David J. Stillman, 2020, PLoS Genetics on p. e1009133

Most-Cited Papers

Transcription under torsion

Jie Ma, Lu Bai, Michelle D. Wang, 2013, Science on p. 1580-1583

Modulation of Fluorescent Protein Chromophores to Detect Protein Aggregation with Turn-On Fluorescence

Yu Liu, Charles H. Wolstenholme, Gregory C. Carter, Hongbin Liu, Hang Hu, Leeann S. Grainger, Kun Miao, Matthew Fares, Conner A. Hoelzel, Hemant P. Yennawar, Gang Ning, Manyu Du, Lu Bai, Xiaosong Li, Xin Zhang, 2018, Journal of the American Chemical Society on p. 7381-7384

Kinetic competition between elongation rate and binding of NELF controls promoter-proximal pausing

Jian Li, Yingyun Liu, Ho Sung Rhee, Saikat Kumar B. Ghosh, Lu Bai, B. Franklin Pugh, David S. Gilmour, 2013, Molecular Cell on p. 711-722

Systematic Study of Nucleosome-Displacing Factors in Budding Yeast

Chao Yan, Hengye Chen, Lu Bai, 2018, Molecular Cell on p. 294-305.e4

Dissociation rate compensation mechanism for budding yeast pioneer transcription factors

Benjamin T. Donovan, Hengye Chen, Caroline Jipa, Lu Bai, Michael G. Poirier, 2019, eLife

Stochastic expression and epigenetic memory at the yeast HO promoter

Qian Zhang, Youngdae Yoon, Yaxin Yu, Emily J. Parnell, Juan Antonio Raygoza Garay, Michael M. Mwangi, Frederick R. Cross, David J. Stillman, Lu Bai, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 14012-14017

Regulation of cell-to-cell variability in divergent gene expression

Chao Yan, Shuyang Wu, Christopher Pocetti, Lu Bai, 2016, Nature Communications

Decoupling of divergent gene regulation by sequence-specific DNA binding factors

Chao Yan, Daoyong Zhang, Juan Antonio Raygoza Garay, Michael M. Mwangi, Lu Bai, 2015, Nucleic Acids Research on p. 7292-7305

Interallelic interaction and gene regulation In budding yeast

Daoyong Zhang, Lu Bai, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 4428-4433

Three distinct mechanisms of long-distance modulation of gene expression in yeast

Manyu Du, Qian Zhang, Lu Bai, 2017, PLoS Genetics on p. e1006736