Ying Gu

Associate Professor, Biochemistry and Molecular Biology

Ying Gu

Research Summary

Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

Graduate Students

Huck Institutes Affiliations

Links

Publication Tags

Cellulose Cellulose Synthase Arabidopsis Microtubules Proteins Endocytosis Clathrin Biosynthesis Cells Cell Membrane Alleles Mutants Cell Wall Plasma Membrane Plant Cells Microfibrils Mechanistic Target Of Rapamycin Complex 1 Synthesis Phosphorylation Acids Membrane Proteins N (2,3 Dihydro 2,6 Dimethyl 1h Inden 1 Yl) 6 (1 Fluoroethyl) 1,3 Polysaccharides Endo 1,4 Beta Glucanase N (2 Methoxybenzyl) 2 (Phenylthio)Acetamide

Most Recent Papers

Impact of acidic pH on plant cell wall polysaccharide structure and dynamics

Pyae Phyo, Ying Gu, Mei Hong, 2019, Cellulose on p. 291-304

CSI1, PATROL1, and exocyst complex cooperate in delivery of cellulose synthase complexes to the plasma membrane

Xiaoyu Zhu, Shundai Li, Songqin Pan, Xiaoran Xin, Ying Gu, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. E3578-E3587

Cellulose synthase complexes act in a concerted fashion to synthesize highly aggregated cellulose in secondary cell walls of plants

Shundai Li, Logan Bashline, Yunzhen Zheng, Xiaoran Xin, Shixin Huang, Zhaosheng Kong, Seong Kim, Daniel J. Cosgrove, Ying Gu, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 11348-11353

Differential regulation of clathrin and its adaptor proteins during membrane recruitment for endocytosis

Chao Wang, Tianwei Hu, Xu Yan, Tingting Meng, Yutong Wang, Qingmei Wang, Xiaoyue Zhang, Ying Gu, Clara Sánchez-Rodríguez, Astrid Gadeyne, Jinxing Lin, Staffan Persson, Daniël van Damme, Chuanyou Li, Sebastian Y. Bednarek, Jianwei Pan, 2016, Plant physiology on p. 215-229

The TWD40-2 protein and the AP2 complex cooperate in the clathrin-mediated endocytosis of cellulose synthase to regulate cellulose biosynthesis

Logan Bashline, Shundai Li, Xiaoyu Zhu, Ying Gu, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 12870-12875

ATF4 gene network mediates cellular response to the anticancer PAD inhibitor YW3-56 in triple-negative breast cancer cells

Shu Wang, Xiangyun Amy Chen, Jing Hu, Jian Kang Jiang, Yunfei Li, Ka Yim Chan-Salis, Ying Gu, Gong Chen, Craig Thomas, Benjamin Franklin Pugh, Yanming Wang, 2015, Molecular Cancer Therapeutics on p. 877-888

Using the split-ubiquitin yeast two-hybrid system to test protein–protein interactions of transmembrane proteins

Logan Bashline, Ying Gu, 2015, Methods in Molecular Biology on p. 143-158

Acetobixan, an inhibitor of cellulose synthesis identified by microbial bioprospecting

Ye Xia, Lei Lei, Chad Brabham, Jozsef Stork, James Strickland, Adam Ladak, Ying Gu, Ian Wallace, Seth DeBolt, 2014, PloS one

The jiaoyao1 mutant is an allele of korrigan1 that abolishes endoglucanase activity and affects the organization of both cellulose microfibrils and microtubules in Arabidopsis

Lei Lei, Tian Zhang, Richard Strasser, Christopher M. Lee, Martine Gonneau, Lukas Mach, Samantha Vernhettes, Seong Kim, Daniel J. Cosgrove, Shundai Li, Ying Gu, 2014, Plant Cell on p. 2601-2616

Indaziflam Herbicidal Action

Chad Brabham, Lei Lei, Ying Gu, Jozsef Stork, Michael Barrett, Seth De Bolt, 2014, Plant Physiology on p. 1177-1185

High-Impact Papers

Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes

Shundai Li, Lei Lei, Chris R. Somerville, Ying Gu, 2012, Proceedings of the National Academy of Sciences of the United States of America on p. 185-190

Identification of a cellulose synthase-associated protein required for cellulose biosynthesis

Ying Gu, Nick Kaplinsky, Martin Bringmann, Alex Cobb, Andrew Carroll, Arun Sampathkumar, Tobias I. Baskin, Staffan Persson, Chris R. Somerville, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 12866-12871

Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target of rapamycin complex 1 activity

Yuji Wang, Pingxin Li, Shu Wang, Jing Hu, Xiangyun Amy Chen, Jianhui Wu, Megan Fisher, Kira Oshaben, Na Zhao, Ying Gu, Dong Wang, Gong Chen, Yanming Wang, 2012, Journal of Biological Chemistry on p. 25941-25953

The endocytosis of cellulose synthase in arabidopsis is dependent on μ2, a clathrin-mediated endocytosis adaptin

Logan Bashline, Shundai Li, Charles T. Anderson, Lei Lei, Ying Gu, 2013, Plant Physiology on p. 150-160

AtPRK2 promotes ROP1 activation via RopGEFs in the control of polarized pollen tube growth

Fang Chang, Ying Gu, Hong Ma, Zhenbiao Yang, 2013, Molecular plant on p. 1187-1201

Complexes with mixed primary and secondary cellulose synthases are functional in Arabidopsis plants

Andrew Carroll, Nasim Mansoori, Shundai Li, Lei Lei, Samantha Vernhettes, Richard G.F. Visser, Chris Somerville, Ying Gu, Luisa M. Trindade, 2012, Plant Physiology on p. 726-737

The jiaoyao1 mutant is an allele of korrigan1 that abolishes endoglucanase activity and affects the organization of both cellulose microfibrils and microtubules in Arabidopsis

Lei Lei, Tian Zhang, Richard Strasser, Christopher M. Lee, Martine Gonneau, Lukas Mach, Samantha Vernhettes, Seong Kim, Daniel J. Cosgrove, Shundai Li, Ying Gu, 2014, Plant Cell on p. 2601-2616

CELLULOSE SYNTHASE INTERACTIVE3 regulates cellulose biosynthesis in both a microtubule-dependent and microtubule-independent manner in arabidopsis

Lei Lei, Shundai Li, Juan Du, Logan Bashline, Ying Gu, 2013, Plant Cell on p. 4912-4923

Cellulose synthase complexes act in a concerted fashion to synthesize highly aggregated cellulose in secondary cell walls of plants

Shundai Li, Logan Bashline, Yunzhen Zheng, Xiaoran Xin, Shixin Huang, Zhaosheng Kong, Seong Kim, Daniel J. Cosgrove, Ying Gu, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 11348-11353

Indaziflam Herbicidal Action

Chad Brabham, Lei Lei, Ying Gu, Jozsef Stork, Michael Barrett, Seth De Bolt, 2014, Plant Physiology on p. 1177-1185