Camilla Hughes
Assistant Professor of Reproductive Biology
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306 Animal, Veterinary, and Biomedical Sciences
University Park, - chkh@psu.edu
- 814-865-7024
Research Summary
Reproductive biology, ovarian function, and reproductive-immune interaction
Huck Affiliations
- Molecular, Cellular, and Integrative Biosciences
- Integrative and Biomedical Physiology
- Center for Reproductive Biology and Health
Links
Most Recent Publications
Double knockout of steroidogenic factor 1 (SF-1; NR5A1) and liver receptor homolog 1 (LRH-1; NR5A2) in the mouse ovary results in infertility due to disruption of follicle development and ovulation.
Fanny Morin, Camilla Hughes, Vickie Roussel, Nicholas Gevry, Bruce Murphy, 2025, Biology of Reproduction
IFNT-dependent and-independent changes in the CL of early pregnancy
Camilla Hughes, A Hellmers, M daSilva, T Ott, J Pate, 2025, Biology of Reproduction on p. 12 pgs
Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve
Camilla H.K. Hughes, Olivia E. Smith, Marie Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy, 2023, Proceedings of the National Academy of Sciences of the United States of America
Review: Luteal prostaglandins: mechanisms regulating luteal survival and demise in ruminants
Joy Lee Pate, C. H.K. Hughes, 2023, Animal
Liver receptor homolog 1 (LRH-1) regulates follicle vasculature during ovulation in mice
Adrian Guzmán, Camilla H.K. Hughes, Bruce D. Murphy, 2022, Reproduction on p. 283-289
Insights from two independent transcriptomic studies of the bovine corpus luteum during pregnancy
Camilla H.K. Hughes, Megan A. Mezera, Milo C. Wiltbank, Joy Lee Pate, 2022, Journal of Animal Science
Form of Supplemental Selenium Affects the Expression of mRNA Transcripts Encoding Selenoproteins, and Proteins Regulating Cholesterol Uptake, in the Corpus Luteum of Grazing Beef Cows
Sarah N. Carr, Benjamin R. Crites, Joy L. Pate, Camilla H.K. Hughes, James C. Matthews, Phillip J. Bridges, 2022, Animals
A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation
Marie Charlotte Meinsohn, Camilla H.K. Hughes, Anthony Estienne, Hatice D. Saatcioglu, David Pépin, Raj Duggavathi, Bruce D. Murphy, 2021, Scientific Reports
Orphan nuclear receptors in angiogenesis and follicular development
Adrian Guzmán, Camilla H.K. Hughes, Bruce D. Murphy, 2021, Reproduction on p. R35-R54
Nuclear receptors: Key regulators of somatic cell functions in the ovulatory process
Camilla H.K. Hughes, Bruce D. Murphy, 2021, Molecular Aspects of Medicine
Most-Cited Papers
Nuclear receptors: Key regulators of somatic cell functions in the ovulatory process
Camilla H.K. Hughes, Bruce D. Murphy, 2021, Molecular Aspects of Medicine
Orphan nuclear receptors in angiogenesis and follicular development
Adrian Guzmán, Camilla H.K. Hughes, Bruce D. Murphy, 2021, Reproduction on p. R35-R54
Molecular profiling demonstrates modulation of immune cell function and matrix remodeling during luteal rescue
Camilla K. Hughes, Samar W. Maalouf, Wansheng Liu, Joy L. Pate, 2019, Biology of Reproduction on p. 1581–1596
A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation
Marie Charlotte Meinsohn, Camilla H.K. Hughes, Anthony Estienne, Hatice D. Saatcioglu, David Pépin, Raj Duggavathi, Bruce D. Murphy, 2021, Scientific Reports
Luteal Lipids Regulate Progesterone Production and May Modulate Immune Cell Function During the Estrous Cycle and Pregnancy
Camilla H.K. Hughes, Remy Bosviel, John W. Newman, Joy L. Pate, 2019, Frontiers in Endocrinology
Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve
Camilla H.K. Hughes, Olivia E. Smith, Marie Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy, 2023, Proceedings of the National Academy of Sciences of the United States of America
Temporal changes in the corpus luteum during early pregnancy reveal regulation of pathways that enhance steroidogenesis and suppress luteolytic mechanisms
C. H.K. Hughes, E. K. Inskeep, J. L. Pate, 2020, Biology of Reproduction on p. 70-84
Review: Luteal prostaglandins: mechanisms regulating luteal survival and demise in ruminants
Joy Lee Pate, C. H.K. Hughes, 2023, Animal
NR5A2 and potential regulatory miRNAs in the bovine CL during early pregnancy
C. H.K. Hughes, A. Rogus, E. K. Inskeep, J. L. Pate, 2021, Reproduction on p. 173-182
Form of Supplemental Selenium Affects the Expression of mRNA Transcripts Encoding Selenoproteins, and Proteins Regulating Cholesterol Uptake, in the Corpus Luteum of Grazing Beef Cows
Sarah N. Carr, Benjamin R. Crites, Joy L. Pate, Camilla H.K. Hughes, James C. Matthews, Phillip J. Bridges, 2022, Animals
News Articles Featuring Camilla Hughes
Aug 11, 2023
Newly identified protein function may reveal understanding of lifetime fertility
A protein in mouse ovaries regulates the formation of the ovarian follicle reserve, which comprises a mammal’s lifetime supply of egg cells and surrounding support cells, according to new study conducted by a U.S.-Canadian team.
Full Article