People: Molecular Evolutionary Genetics

Sarah Ades

Associate Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.

Etya Amsalem

Assistant Professor of Entomology
The evolutionary development and the mechanistic basis of social behavior in insects using an integrative approach encompassing chemical, genetic and physiological tools

Charles Anderson

Associate Professor of Biology
In vivo imaging of plant cell wall dynamics. Molecular genetic analysis of genes involved in cell growth. Cell wall biosynthesis in dividing cells. Cell wall engineering for sustainable bioenergy production.

Raquel Assis

Assistant Professor of Biology
Evolutionary genomics, molecular evolution, and bioinformatics. Particularly interested in how new functions evolve after gene duplication.

Michael Axtell

Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets

Lu Bai

Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.

Craig Cameron

Berg Professor of Biochemistry and Molecular Biology; Eberly Chair in Biochemistry and Molecular Biology
Defining the molecular details of genome replication in positive-strand RNA viruses and identifying components of this process suitable for antiviral drug development.

John Carlson

Professor of Molecular Genetics; Director, Schatz Center for Tree Molecular Genetics
Genome mapping, including genetic linkage mapping, molecular cytogenetics; studies of genetic diversity in forests.

Douglas Cavener

Professor and Verne M. Willaman Dean, Eberly College of Science; Chair of the Genetics Program
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Gong Chen

Professor and Verne M. Willaman Chair in Life Sciences
Developing innovative technologies for brain repair using newly established in vivo cell conversion technology.

Surinder Chopra

Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.

Michael DeGiorgio

Assistant Professor of Biology
Development and application of mathematical models, statistical methods, and algorithms to uncover genomic footprints of past evolutionary events.

Claude dePamphilis

Professor of Biology
Genomics, bioinformatics, and molecular evolution. Origin and diversification of flowers and developmental pathways. Comparative genomics of plants, organelles, and plant gene families. Genomics, evolution, and functional biology of parasitic plants.

Robert Eckhardt

Professor
Genetic and environmental influences on growth and development in human populations.

Gregory Ferry

Stanley Person Professor of Biochemistry and Molecular Biology
Enzymology and molecular genetics of anaerobic microbes from the Archaea domain

Majid Foolad

Professor of Plant Genetics
Genetic characterization of resistance/tolerance to biotic/abiotic stresses, and genes/QTLs contributing to tomato fruit quality. Investigation of genes/QTLs for directed crop improvement and germplasm enhancement. Tomato cultivar development & release.

David Geiser

Professor of Plant Pathology
Molecular evolutionary genetics of pathogenic and toxigenic fungi.

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

David Gilmour

Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Santhosh Girirajan

Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
To understand the genetic basis of neurodevelopmental disorders

Christina M Grozinger

Director of the Center for Pollinator Research; Distinguished Professor of Entomology
Genomics of social behavior and health in bees

Ying Gu

Associate Professor, Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

Mark Guiltinan

J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.

Wendy Hanna-Rose

Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans

Ross Hardison

Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.

Heather Hines

Assistant Professor, Biology and Entomology
Genetics of adaptive mimetic color pattern variation in butterflies and bumble bees

Kelli Hoover

Professor of Entomology
Invasive species of forest insects; plant-insect-entomopathogen interactions; impacts of plants on pathogenesis; biological control of hemlock woolly adelgid

Yifei Huang

Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.

David Huff

Professor of Turfgrass Breeding and Genetics
Population genetics. Plant evolution and ecology. Crop improvement. Physiological tolerance to biotic and abiotic stress.

Timothy Jegla

Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.

Helen Kamens

Assistant Professor of Biobehavioral Health
Identification of genetic mechanisms that contribute to complex behaviors with a special emphasis on alcohol and tobacco use.

Seogchan Kang

Professor of Plant Pathology & Environmental Microbiology
Genetic and cellular mechanisms underpinning plant-fungal interactions with Arabidopsis thaliana and Fusarium oxysporum as a model system. Molecular genetics and comparative genomics of fungal plant pathogens. Bioinformatics.

Vivek Kapur

Associate Director for Strategic Initiatives, Huck Institutes of the Life Sciences; Huck Distinguished Chair in Global Health; Professor of Microbiology and Infectious Diseases
The basic mechanisms by which pathogenic microbes successfully infect, colonize, and cause disease in their hosts.

Kenneth Keiler

Professor of Biochemistry and Molecular Biology
Small RNAs and protein localization in bacterial development and antimicrobial drug discovery.

Jasna Kovac

Lester Earl and Veronica Casida Career Development Professor of Food Safety; Assistant Professor of Food Science
Integrating epidemiological, microbiological, molecular and omics methods to better understand microbial pathogenic potential, antimicrobial resistance, and epidemiology of foodborne pathogens.

Zhi-Chun Lai

Professor of Biology, Biochemistry and Molecular Biology; Emphasis Area Representative, Cell and Developmental Biology
Signal Transduction, Growth Control, and Cancer Genetics

Todd Lajeunesse

Associate Professor of Biology
Microbial Ecology and Evolution

Tae-Hee Lee

Associate Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin

Scott Lindner

Assistant Professor of Biochemistry & Molecular Biology
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Aimin Liu

Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.

Wansheng Liu

Professor of Genomics
Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.

Bernhard Luscher

Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action

Kateryna Makova

Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Elizabeth McGraw

Director of the Center for Infectious Disease Dynamics; Professor and Huck Scholar in Entomology
The genetics of vector, pathogen and symbiont interactions.

Timothy Meredith

Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.

Anton Nekrutenko

Professor of Biochemistry and Molecular Biology
Evolution of overlapping reading frames in eukaryotic genomes.

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Curtis Omiecinski

Professor of Veterinary & Biomedical Sciences; H. Thomas and Dorothy Willits Hallowell Chair; Emphasis Area Representative, Molecular Toxicology
Nuclear receptor biology and genomics. Xenobiotic Receptor systems that regulate biotransformation, detoxication, cancer predisposition, lipid and energy homeostasis.

Richard Ordway

Professor of Molecular Neuroscience and Genetics
Genetic analysis of neural function.

Andrew Patterson

Associate Professor of Molecular Toxicology
The Patterson lab is focused on understanding the host-metabolite-microbiome axis

Robert Paulson

Professor of Veterinary and Biomedical Sciences; Emphasis Area Representative, Genetics
The Paulson lab studies the mechanisms that regulate tissue regeneration with a focus on understanding the response to anemic and hypoxic stress

Gary Perdew

Director of the Center for Molecular Toxicology and Carcinogenesis; John T. and Paige S. Smith Professor in Agricultural Sciences
Mechanisms of receptor-mediated carcinogenesis.

Jeffrey Peters

Distinguished Professor of Molecular Toxicology and Carcinogenesis
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis.

Franklin Pugh

Director of the Center for Eukaryotic Gene Regulation; Willaman Professor in Molecular Biology
Biochemistry and genomics of eukaryotic transcription regulation.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joan Richtsmeier

Professsor of Anthropology
Analysis of craniofacial phenotypes.

Melissa Rolls

Chair, Intercollege Graduate Degree Program in Molecular, Cellular and Integrative Biosciences; Director of the Center for Cellular Dynamics; Professor of Biochemistry and Molecular Biology
Subcellular compartmentalization of neurons. The cellular basis of neuronal polarity and neuronal responses to injury including degeneration and regeneration.

Stephen Schaeffer

Professor of Biology
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila

Anthony Schmitt

Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.

Idan Shalev

Assistant Professor of Biobehavioral Health
Interdisciplinary approach to identify mechanisms underpinning the biological embedding of stress across the lifespan with a special focus on biological aging.

Cooduvalli Shashikant

Assistant Director for Graduate Training Initiatives, Huck Institutes of the Life Sciences; Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Molecular and Developmental Biology
Developmental and evolutionary aspects of regulation of patterning genes.

Mark Shriver

Professor of Biological Anthropology
Human population genomics and complex disease mapping.

Moriah L Szpara

Assistant Professor of Biochemistry & Molecular Biology
Neurovirology, genomics of pathogen variation, neuron-virus relationships

Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Na Xiong

Associate Professor, Department of Veterinary and Biomedical Science
Development and function of gamma/delta T cells, a class of immune cells with various roles in microbial immunity, inflammation regulation and tumor surveillance.