Mark Guiltinan

J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa

Mark Guiltinan

Research Summary

Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.

Graduate Students

Huck Affiliations

Links

Publication Tags

Genes Cacao Theobroma Cacao Leaves Arabidopsis Starch Polymers 1,4 Alpha Glucan Branching Enzyme Genome Genomics Salicylic Acid Genotype Infection Transcription Factors Phytophthora Flavonoids Mutants Anti Bacterial Agents Pathogens Phenotype Fungi Gene Expression Rna Tissues Proteins

Most Recent Papers

Gene Expression Modularity Reveals Footprints of Polygenic Adaptation in Theobroma cacao.

T Hämälä, Mark Guiltinan, James Marden, Siela Maximova, Claude dePamphilis, P Tiffin, 2020, Molecular biology and evolution on p. 110-123

Metabolomic profile of cacao cell suspensions growing in blue light/dark conditions with potential in food biotechnology

Adriana M. Gallego, Luisa F. Rojas, Héctor A. Rodriguez, Conrado Mora, Lucía Atehortúa, Aura I. Urrea, Mark Guiltinan, Siela Maximova, Emmanuel Gaquerel, Martha Zuluaga, Natalia Pabón-Mora, 2019, Plant Cell, Tissue and Organ Culture on p. 275-294

Resistant and susceptible cacao genotypes exhibit defense gene polymorphism and unique early responses to Phytophthora megakarya inoculation

Désiré N. Pokou, Andrew S. Fister, Noah Winters, Mathias Tahi, Coulibaly Klotioloma, Aswathy Sebastian, James Harold Marden, Siela Maximova, Mark Guiltinan, 2019, Plant molecular biology on p. 499-516

Widely distributed variation in tolerance to Phytophthora palmivora in four genetic groups of cacao

Andrew Fister, Mariela Leandro-Munoz, Dapeng Zhang, James Marden, Peter Tiffin, Claude dePamphilis, Siela Maximova, Mark Guiltinan, 2019, TREE GENETICS & GENOMES

Transcriptomic analyses of cacao cell suspensions in light and dark provide target genes for controlled flavonoid production

Adriana M. Gallego, Luisa F. Rojas, Oriana Parra, Héctor A. Rodriguez, Juan C. Mazo Rivas, Aura Inés Urrea, Lucía Atehortúa, Andrew S. Fister, Mark Guiltinan, Siela Maximova, Natalia Pabón-Mora, 2018, Scientific reports

Transient expression of CRISPR/Cas9 machinery targeting TcNPR3 enhances defense response in theobroma cacao

Andrew S. Fister, Lena Landherr, Siela N. Maximova, Mark J. Guiltinan, 2018, Frontiers in Plant Science

Gallego AM, Rojas LF, Parra O, Rodriguez HA, Mazo Rivas JC, Urrea AI, Atehortúa L, Fister AS, Guiltinan MJ, Maximova SN et al: Transcriptomic analyses of cacao cell suspensions in light and dark provide target genes for controlled flavonoid production. 2018, 8(1):13575. Open Access Link

Mark Guiltinan, 2018, Scientific Reports

Pervasive effects of a dominant foliar endophytic fungus on host genetic and phenotypic expression in a tropical tree (reprint)

LC Mejía, EA Herre, JP Sparks, K Winter, MN García, SA Van Bael, Joseph Stitt, Z Shi, Y Zhang, Mark Guiltinan, SN Maximova, 2017, Recent Advances in Symbiosis Research: Integrative Approaches on p. 52-67

Phytophthora megakarya and Phytophthora palmivora, Closely Related Causal Agents of Cacao Black Pod Rot, Underwent Increases in Genome Sizes and Gene Numbers by Different Mechanisms

Shahin Ali, Jonathan Shao, David Lary, Brent Kronmiller, Danyu Shen, Mary Strem, Ishmael Amoako-Attah, Andrew Akrofi, B. Begoude, G. ten Hoopen, Klotioloma Coulibaly, Boubacar Kebe, Rachel Melnick, Mark Guiltinan, Brett Tyler, Lyndel Meinhardt, Bryan Bailey, 2017, Genome Biology and Evolution on p. 536-557

Protocol

Andrew S. Fister, Zi Shi, Yufan Zhang, Emily E. Helliwell, Siela N. Maximova, Mark J. Guiltinan, 2016, Plant Methods

Most-Cited Papers

The genome of Theobroma cacao

Xavier Argout, Jerome Salse, Jean Marc Aury, Mark Guiltinan, Gaetan Droc, Jerome Gouzy, Mathilde Allegre, Cristian Chaparro, Thierry Legavre, Siela Maximova, Michael Abrouk, Florent Murat, Olivier Fouet, Julie Poulain, Manuel Ruiz, Yolande Roguet, Maguy Rodier-Goud, Jose Fernandes Barbosa-Neto, Francois Sabot, Dave Kudrna, Jetty Siva S. Ammiraju, Stephan C. Schuster, John Edward Carlson, Erika Sallet, Thomas Schiex, Anne Dievart, Melissa Kramer, Laura Gelley, Zi Shi, Aurélie Bérard, Christopher Viot, Michel Boccara, Ange Marie Risterucci, Valentin Guignon, Xavier Sabau, Michael Axtell, Zhaorong Ma, Yufan Zhang, Spencer Brown, Mickael Bourge, Wolfgang Golser, Xiang Song, Didier Clement, Ronan Rivallan, Mathias Tahi, Joseph Moroh Akaza, Bertrand Pitollat, Karina Gramacho, Anglique D'Hont, Dominique Brunel, Diogenes Infante, Ismael Kebe, Pierre Costet, Rod Wing, W. Richard McCombie, Emmanuel Guiderdoni, Francis Quetier, Olivier Panaud, Patrick Wincker, Stephanie Bocs, Claire Lanaud, 2011, Nature Genetics on p. 101-108

Proanthocyanidin synthesis in Theobroma cacao

Yi Liu, Zi Shi, Siela Maximova, Mark J. Payne, Mark J. Guiltinan, 2013, BMC plant biology

Genome and secretome analysis of the hemibiotrophic fungal pathogen, Moniliophthora roreri, which causes frosty pod rot disease of cacao

Lyndel W. Meinhardt, Gustavo Gilson L. Costa, Daniela P.T. Thomazella, Paulo José P.L. Teixeira, Marcelo F. Carazzolle, Stephan C. Schuster, John E. Carlson, Mark J. Guiltinan, Piotr Mieczkowski, Andrew Farmer, Thiruvarangan Ramaraj, Jayne Crozier, Robert E. Davis, Jonathan Shao, Rachel L. Melnick, Gonçalo A.G. Pereira, Bryan A. Bailey, 2014, BMC genomics

Pervasive effects of a dominant foliar endophytic fungus on host genetic and phenotypic expression in a tropical tree

Luis C. Mejía, Edward A. Herre, Jed P. Sparks, Klaus Winter, Milton N. García, Sunshine A. Van Bael, Joseph Stitt, Zi Shi, Yufan Zhang, Mark J. Guiltinan, Siela N. Maximova, 2014, Frontiers in Microbiology

Enhanced somatic embryogenesis in Theobroma cacao using the homologous BABY BOOM transcription factor

Sergio L. Florez, Rachel L. Erwin, Siela N. Maximova, Mark J. Guiltinan, Wayne R. Curtis, 2015, BMC plant biology

Functional analysis of the theobroma cacao NPR1 gene in arabidopsis

Zi Shi, Siela Maximova, Yi Liu, Joseph Verica, Mark Guiltinan, 2010, BMC Plant Biology

Biodegradable polyphosphazenes containing antibiotics

Zhicheng Tian, Yufan Zhang, Xiao Liu, Chen Chen, Mark Guiltinan, Harry R. Allcock, 2013, Polymer Chemistry on p. 1826-1835

Deficiency of maize starch-branching enzyme i results in altered starch fine structure, decreased digestibility and reduced coleoptile growth during germination

Huan Xia, Marna Yandeau-Nelson, Donald B. Thompson, Mark J. Guiltinan, 2011, BMC plant biology

Starch-branching enzyme IIa is required for proper diurnal cycling of starch in leaves of maize

Marna D. Yandeau-Nelson, Lieve Laurens, Zi Shi, Huan Xia, Alison M. Smith, Mark J. Guiltinan, 2011, Plant physiology on p. 479-490

The salicylic acid receptor NPR3 is a negative regulator of the transcriptional defense response during early flower development in Arabidopsis

Zi Shi, Siela Maximova, Yi Liu, Joseph Verica, Mark J. Guiltinan, 2013, Molecular plant on p. 802-816

News Articles Featuring Mark Guiltinan

New way to identify disease-resistant genes in chocolate-producing trees

Chocolate-producing cacao trees that are resistant to a major pathogen were identified by an international team of plant geneticists. The NSF-funded finding points the way for plant breeders to develop trees that are tolerant of the disease.

Novel way to ID disease-resistance genes in chocolate-producing trees found

Chocolate-producing cacao trees that are resistant to a major pathogen were identified by an international team of plant geneticists. The findings point the way for plant breeders to develop trees that are tolerant of the disease.

These Kids Have Come 500 Miles To Do Science And Make A Difference

The road between Arauquita, relatively near Colombia’s border with Venezuela, and the nation’s capital in Bogota stretches over 800 kilometers (500 miles), but for one week in October, a special group bridged that gap in more ways than one.

Gene editing could save Ghana’s cocoa from extinction, scientists say

A new study warns that climate change could drive Ghana’s cocoa (cacao) industry to extinction — a fate that scientists say could be reversed through gene editing.

Guiltinan, Maximova receive the 2019 Kopp International Achievement Award

Mark Guiltinan, professor of plant molecular biology, and Siela Maximova, research professor of plant biotechnology, both in the College of Agricultural Sciences, are the recipients of Penn State's 2019 W. LaMarr Kopp International Achievement Award.