Amie Boal

Professor of Chemistry and of Biochemistry and Molecular Biology

Amie Boal

Research Summary

The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.

Huck Affiliations

Links

Publication Tags

Enzymes Proteins Oxygenases Iron Hydrogen Carbon Protein Arginine X Rays Glutarates Hydroxylation Ketoglutaric Acids Mixed Function Oxygenases Catalytic Domain Substrates Carbon Atom S Adenosylmethionine Ligands Hydrogen Atom Chemical Transformation Oxygen Ferryl Iron Halogenation Cofactor Alkenes

Most Recent Publications

Use of Noncanonical Tyrosine Analogues to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

Chi Yun Lin, Angel L. Muñoz Hernández, Tatiana N. Laremore, Alexey Silakov, Carsten Krebs, Amie K. Boal, J. Martin Bollinger, 2022, ACS Catalysis on p. 6968-6979

Structural insights into auxiliary cofactor usage by radical S-adenosylmethionine enzymes

Vivian Robert Jeyachandran, Amie K. Boal, 2022, Current Opinion in Chemical Biology

Progress Toward Understanding Protein Control of Reaction Outcome in the Diverse Reactivity of Iron(II)- and 2-Oxoglutarate-dependent Oxygenases

J. M. Bollinger, Carsten Krebs, Amie K. Boal, Alexey Silakov, John C. Price, Megan L. Matthews, Wei Chen Chang, Ryan J. Martinie, Juan Pan, Noah P. Dunham, Eliott S. Wenger, Rachelle A. Copeland, Chi Yun Lin, 2022, FASEB Journal

Molly J. McBride, Mrutyunjay A. Nair, Debangsu Sil, Jeffrey W. Slater, Monica E. Neugebauer, Michelle C.Y. Chang, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, 2022, Biochemistry on p. 689-702

Hayley L. Knox, Erica K. Sinner, Craig A. Townsend, Amie K. Boal, Squire J. Booker, 2022, Nature on p. 343-348

Nathaniel R. Braffman, Terry B. Ruskoski, Katherine M. Davis, Nathaniel R. Glasser, Cassidy Johnson, C. Denise Okafor, Amie K. Boal, Emily P. Balskus, 2022, eLife

Cody T. Lloyd, David F. Iwig, Bo Wang, Matteo Cossu, William W. Metcalf, Amie K. Boal, Squire J. Booker, 2022, Nature

Terry B. Ruskoski, Amie K. Boal, 2021, Journal of Biological Chemistry

Rachelle Copeland, Katherine Davis, Tokufu Shoda, Elizabeth Blaesi, A Boal, Carsten Krebs, J. Bollinger, 2021, Journal of the American Chemical Society on p. 2293-2303

Emery T. Usher, Nafiseh Sabri, Roman Rohac, Amie K. Boal, Tanja Mittag, Scott A. Showalter, 2021, Journal of Biological Chemistry

Most-Cited Papers

Franklin D. Fuller, Sheraz Gul, Ruchira Chatterjee, E. Sethe Burgie, Iris D. Young, Hugo Lebrette, Vivek Srinivas, Aaron S. Brewster, Tara Michels-Clark, Jonathan A. Clinger, Babak Andi, Mohamed Ibrahim, Ernest Pastor, Casper De Lichtenberg, Rana Hussein, Christopher J. Pollock, Miao Zhang, Claudiu A. Stan, Thomas Kroll, Thomas Fransson, Clemens Weninger, Markus Kubin, Pierre Aller, Louise Lassalle, Philipp Bräuer, Mitchell D. Miller, Muhamed Amin, Sergey Koroidov, Christian G. Roessler, Marc Allaire, Raymond G. Sierra, Peter T. Docker, James M. Glownia, Silke Nelson, Jason E. Koglin, Diling Zhu, Matthieu Chollet, Sanghoon Song, Henrik Lemke, Mengning Liang, Dimosthenis Sokaras, Roberto Alonso-Mori, Athina Zouni, Johannes Messinger, Uwe Bergmann, Amie K. Boal, J. Martin Bollinger, Carsten Krebs, Martin Högbom, George N. Phillips, Richard D. Vierstra, Nicholas K. Sauter, Allen M. Orville, Jan Kern, Vittal K. Yachandra, Junko Yano, 2017, Nature Methods on p. 443-449

Wei Chen Chang, Yisong Guo, Chen Wang, Susan E. Butch, Amy C. Rosenzweig, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, 2014, Science on p. 1140-1144

Andrew J. Mitchell, Qin Zhu, Ailiena O. Maggiolo, Nikhil R. Ananth, Matthew L. Hillwig, Xinyu Liu, Amie K. Boal, 2016, Nature Chemical Biology on p. 636-640

Andrew J. Mitchell, Noah P. Dunham, Ryan J. Martinie, Jonathan A. Bergman, Christopher J. Pollock, Kai Hu, Benjamin D. Allen, Wei Chen Chang, Alexey Silakov, J. Martin Bollinger, Carsten Krebs, Amie K. Boal, 2017, Journal of the American Chemical Society on p. 13830-13836

Noah P. Dunham, Wei Chen Chang, Andrew J. Mitchell, Ryan J. Martinie, Bo Zhang, Jonathan A. Bergman, Lauren J. Rajakovich, Bo Wang, Alexey Silakov, Carsten Krebs, Amie K. Boal, J. Martin Bollinger, 2018, Journal of the American Chemical Society on p. 7116-7126

Tai L. Ng, Roman Rohac, Andrew J. Mitchell, Amie K. Boal, Emily P. Balskus, 2019, Nature on p. 94-99

Yu Liu, Matthew Fares, Noah P. Dunham, Zi Gao, Kun Miao, Xueyuan Jiang, Samuel S. Bollinger, Amie K. Boal, Xin Zhang, 2017, Angewandte Chemie - International Edition on p. 8672-8676

Mechanisms of 2-oxoglutarate-dependent oxygenases: The hydroxylation paradigm and beyond

J. Martin Bollinger, Wei Chen Chang, Megan L. Matthews, Ryan J. Martinie, Amie K. Boal, Carsten Krebs, 2015, on p. 95-122

Yu Liu, Kun Miao, Noah P. Dunham, Hongbin Liu, Matthew Fares, Amie K. Boal, Xiaosong Li, Xin Zhang, 2017, Biochemistry on p. 1585-1595

Erica L. Schwalm, Tyler L. Grove, Squire J. Booker, Amie K. Boal, 2016, Science on p. 309-312