Providing training, assistance and expertise in crystallizing and determining the three-dimensional structures of proteins and other biological macromolecules
X-ray crystallography is the chief method for determining the atomic resolution three-dimensional structures of biological macromolecules. The focus of the facility is to provide the necessary infrastructure and support for individual investigators to undertake single crystal X-ray structural studies. We provide instrumentation, training and collaboration for:
- Protein characterization including dynamic light scattering, differential scanning calorimetry, bio-layer interferometry and circular dichroism
Binding studies using isothermal titration calorimetry
- Robotic crystallization, incubators, UV and digital microscopes
- Robotic imaging
- Diffraction data collection and processing
- Structure determination and analysis
- Molecular modeling
- Small angle X-ray scattering
Our experienced staff are available to train researchers to use equipment and to assist project development and research.
Please contact the Facility to schedule equipment use or training.