Penn State University

X-Ray Crystallography Facility

Providing training, assistance and expertise in crystallizing and determining the three-dimensional structures of proteins and other biological macromolecules
 
X-ray crystallography is the chief method for determining the atomic resolution three-dimensional structures of biological macromolecules. The focus of the facility is to provide the necessary infrastructure and support for individual investigators to undertake single crystal X-ray structural studies. We provide instrumentation, training and collaboration for:
  • Protein characterization including dynamic light scattering, differential scanning calorimetry, bio-layer interferometry and circular dichroism
  • Binding studies using isothermal titration calorimetry

  • Robotic crystallization, incubators, UV and digital microscopes 
  • Robotic imaging
  • Diffraction data collection and processing
  • Structure determination and analysis
  • Molecular modeling
  • Small angle X-ray scattering
 
 
Our experienced staff are available to train researchers to use equipment and to assist project development and research.
 
 
 
Scheduling
Please contact the Facility to schedule equipment use or training.