News

DNA stuck in the gears of the RNA production machine

Precise control of gene expression — ensuring that cells make the correct components in the right amount and at the right time — is vital for all organisms to function properly. Cells must regulate how genes encoded in the sequence of DNA are made into RNA molecules that can carry out cellular functions on their own or be further processed into proteins.

Novel method of imaging silicon anode degradation may lead to better batteries

A novel method of characterizing the structural and chemical evolution of silicon and a thin layer that governs battery stability may help resolve issues that prevent using silicon for high-capacity batteries, according to a group of researchers.

New images of canine parvovirus may help predict how virus jumps to new species

​Canine parvovirus (CPV) is a highly infectious pathogen that causes severe diseases in unvaccinated dogs, including inflammation of the heart and acute gastrointestinal illness. Originating in cats, the virus is a rare example of a DNA-based virus that can jump between species, and a team of researchers’ discovery may help in predicting this and the virus’ ability to evolve, which could have implications for current vaccines used in dogs.

Regulating the ribosomal RNA production line

Cryo-electron microscopy study allows researchers to visualize structural changes in an E. coli enzyme synthesizing ribosomal RNA that shift it between turbo- and slow-modes depending on the bacteria’s growth rate

Altered 'coat' disguises fatal brain virus from neutralizing antibodies

A genetic modification in the ‘coat’ of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers.

Scientists solve structure enabling cyanobacteria to thrive in low light

Scientists have determined the structure of the protein complex that gives cyanobacteria their unique ability to convert weak, filtered sunlight into useable energy. Their findings could one day be used to engineer crops that thrive under low-light conditions.

Virus may jump species through 'rock-and-roll' motion with receptors

Like a janitor thumbing through a keychain to find just the right key to open a lock, the "rock-and-roll" motion of the canine parvovirus during the binding process may help explain how the virus can find the spot on a receptor to infect not just dogs, but multiple species, according to an international team of researchers.

Resolution Revolution: Penn State welcomes a new era of atomic-level imaging with cryo EM facility

Using extreme cold to arrest fluid samples in motion, cryo EM allows researchers to see proteins, clusters of molecules, and viruses with astounding clarity—to the point where individual atoms may become visible.

Partnership announced between Commonwealth Campuses and shared facilities

The Office of the Vice President for Research at Penn State has announced the launch of a new program to support increased usage of shared core facilities and services by faculty at the Commonwealth Campuses.

Convergence of Transmission Electron Microscopy Methods for Materials and Life Sciences

On November 3rd there will be a workshop to discuss common transmission electron microscopy methods and new instrumentation. This workshop is part of the new Common Vision initiative established by MRI and the Huck Institutes to foster collaboration between Life Sciences and Materials Sciences.