Research

Recent research publications include:

Jennifer Park, Michael B. Cleary, Danyang Li, Joseph A. Mattocks, Jiansong Xu, Huan Wang, Somshuvra Mukhopadhyay, Eric M. Gale, and Joseph A. Cotruvo, Jr. (2022) A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin. Proc Natl Acad Sci U S A. 2022 Dec 20; 119(51): e2212723119.

Mattocks JA, Jung JJ, Lin CY, Dong Z, Yennawar NH, Featherston ER, Kang-Yun CS, Hamilton TA, Park DM, Boal AK, Cotruvo JA Jr. (2023) Enhanced rare-earth separation with a metal-sensitive lanmodulin dimer. Nature. Jun;618(7963):87-93. doi: 10.1038/s41586-023-05945-5. Epub 2023 May 31.

Calvin Yeager, Griffin Carter, David W Gohara, Neela H Yennawar, Eric J Enemark, Jamie J Arnold, Craig E Cameron. (2022) Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP Nucleic Acids Res.Nov 11;50(20):11775-11798. doi: 10.1093/nar/gkac105

Atip Lawanprasert, Janna N. Sloand, Mariangely González Vargas, Harminder Singh, Tomer Eldor, Michael A. Miller, Sopida Pimcharoen, Jian Wang, Scott M. Leighow, Justin R. Pritchard, Nikolay V. Dokholyan, Scott H. Medina (2023) Deciphering the Mechanistic Basis for Perfluoroalkyl-Protein Interactions. ChemBioChem, 21 March 2023 https://doi.org/10.1002/cbic.202300159

Jennifer Park, Michael B. Cleary, Danyang Li. (2022) A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin PNAS, Edited by Alison Butler, University of California Santa Barbara, Santa Barbara, CA; December 12, 2022119 (51) e2212723119

Jiansong Xu , Joseph A Cotruvo Jr,(2022) Reconsidering the czcD (NiCo) Riboswitch as an Iron Riboswitch. ACS Bio Med Chem Au. Aug 17;2(4): 376-385

Walker J.A., Wu Y., Potter J.R., Weinert E.E.,(2020) π-Helix controls activity of oxygen-sensing diguanylate cyclases. Biosci Rep, Feb 2020,40(2): BSR20193602

Allison M Williams, Paghav R Poudyal, Philip Bevilacqua. (2021) Long Tracts of Guanines Drive Aggregation of RNA G-Quadruplexes in the Presence of Spermine. Biochemistry. 2021, 60, 36, 2715–2726.

Jian Sun, Marcin Paduch, Sang-Ah Kim, Ryan M. Kramer, Adam F. Barrios, Vincent Lu, Judy Luke, Svitlana Usatyuk, Anthony A Kossiakoff, Song Tan (2018) Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2. PNAS. 115 (40) 10010-10015

Gorman SD, Boehr DD. 2019 Energy and Enzyme Activity Landscapes of Yeast Chorismate Mutase at Cellular Concentrations of Allosteric Effectors. Biochemistry. 58(39):4058-4069.

Chi, K. and J.M. Catchmark. 2017. Crystalline nanocellulose/lauric arginate complexes. Carbohydrate Polymers. 175: 320-329.

Glisan, S.L., K.A. Grove, N.H. Yennawar, and J.D. Lambert. 2017. Inhibition of pancreatic lipase by black tea theaflavins: Comparative enzymology and in silico modeling studies. Food Chemistry. 216: 296-300.

Poosarla, V.G., T. Li, B.C. Goh, K. Schulten, T.K. Wood, and C.D. Maranas. 2017. Computational de novo design of antibodies binding to a peptide with high affinity. Engineering Science of Biological Systems Biotechnology and Bioengineering.

Badding, E.D., T.L. Grove, L.K. Gadsby, J.W. LaMattina, A.K. Boal, and S.J. Booker. 2017. Rerouting the pathway for the biosynthesis of the side ring system of nosiheptide: The roles of NosI, NosJ, and NosK. Journal of the American Chemical Society. 139 (16): 5896-5905.

Girish, T.S., R.K. McGinty, and S. Tan. 2016. Multivalent interactions by the Set8 histone methyltransferase with its nucleosome substrate. Journal of Molecular Biology. 24;428(8): 1531-43.

Yennawar, N.H., J.A. Fecko, S.A. Showalter, and P.C. Bevilacqua. 2016. A high-throughput biological calorimetry core: Steps to startup, run, and maintain a multi-user facility. Methods in Enzymology. 567: 435-460.

Chandrasekar, V., J.N. Coupland, and R.C. Anantheswaran. 2016. Release kinetics of nisin from chitosan–alginate complex. Journal of Food Science. 81(10): E2503-E2510.

Poyton, M., A.M. Sendecki, X. Cong, and P.S. Cremer. 2016. Cu2+ binds to phosphatidylethanolamine and increases oxidation in lipid membranes. Journal of the American Chemical Society. 138(5): 1584-1590.

Sahu, D., M. Bastidas, C.W. Lawrence, W.G. Noid, and S.A. Showalter. 2016. Assessing coupled protein folding and binding through temperature-dependent isothermal titration calorimetry. Methods in Enzymology. 567: 23-45.

Organtini, L.J., A.B. Allison, T. Lukk, C.R. Parrish, and S. Hafenstein. 2015. Global displacement of canine parvovirus by a host-adapted variant: Structural comparison between pandemic viruses with distinct host ranges. Journal of Virology. 89(3): 1909-12.

Khanna, M.R., F.J. Mattie, K.C. Browder, M.D. Radyk, S.E. Crilly, K.J. Bakerink, S.L. Harper, D.W. Speichder, and C. Thomas. 2015. Spectrin tetramer formation is not required for viable development in Drosophilia. Journal of Biological Chemistry. 290(2): 706-715.

Warui, D., M.E. Pandelia, L. Rajakovich, C. Krebs, J.M. Bollinger, and S. Booker. 2015. Efficient delivery of long-chain fatty aldehydes from the nostopunctiforme acyl-acyl carrier protein reductase to its cognate aldehyde deformylating oxygenase. Biochemistry. 54(4): 1006-1015.