Collage for hero banner of microbes

One Health Microbiome Center

As one of the largest and most active organizations in the field, the internationally awarded One Health Microbiome Center has a mission to optimize, accelerate, and disseminate long-lasting applications and knowledge on the microbiome.

Microbiomes are communities of microorganisms (e.g., bacteria, fungi, viruses, archaea, and protozoa) that inhabit an environment, including plants, animals, soils, oceans, and our homes. As we peer into our bodies, half of the cells in a human are microbes, and the gene catalogue of these human-associated microbes dwarfs that of our own human genome by at least 100-fold. Members of the microbiome can range from helpful to harmful, but notably the vast majority do not cause disease. As a collective, microbial assemblages and their genomes have profound impacts on solutions related to agricultural production, human chronic diseases, and ecosystem stability, among others. As we break ground on understanding how these diverse communities impact life, it is clear that the new study of the microbiome is central to biological systems, education, and applications in a rapidly changing world.

The center deeply embodies my vision for growing interdisciplinary excellence

—Penn State President Neeli Bendapudi, November 2024

550

Members

$224M

Awarded Funding

42+

Departments

100

Country Collaborations

7

American Academy of Microbiology Fellows

2000+

Publications in a Five-Year Period

First Ph.D

In Microbiome Science

Pierce Prize

First Ever Awarded to a Center, Not an Individual

News

Q&A: How can microbiome science solve problems in agriculture?

Decades of research has shown promise for using microbiome science to solve several problems facing agriculture, but these findings have not yet been translated to practical recommendations for growers, according to a team of scientists in Penn State’s College of Agricultural Sciences.

Huck associate director elected fellow in American Academy of Microbiology

Andrew Patterson, John T. and Paige S. Smith Professor in the College of Agricultural Sciences, has been elected as a fellow in the American Academy of Microbiology. Fellows of the American Academy of Microbiology, an honorific leadership group within the American Society for Microbiology, are elected annually through a highly selective, peer-review process, based on their records of scientific achievement and original contributions that have advanced microbiology.

Flipping and reversing mini-proteins could improve disease treatment

For the microbe that gives rise to tuberculosis, a team of researchers from Penn State and The University of Minnesota Medical School found that a potential solution may be chemically changing the structure of a naturally occurring peptide — a building block of proteins — to make it a more stable and effective antimicrobial agent, while reducing potential toxicity to human cells.

Too many saturated fats may be more harmful than too many refined carbohydrates

In recent years, many media reports and social media influencers have emphasized the dangers of eating too many carbohydrates. Though a carbohydrate-heavy diet can be harmful, consuming too many fats may cause more health problems, according to a study in mice led by researchers in the Penn State Department of Nutritional Sciences.