The Automated Biological Calorimetry Facility is hosting an open house on Sept. 6, 2013, 8 Althouse, from 1-3pm.
September 6, 2013 @ 02:00 pm
to 04:00 pm
Calorimetry facility open house - Sep 6th 1 to 3PM, 8 Althouse
8 Althouse
Our friendly staff will offer free training opportunities and are eager to discuss how Automated Biological Calorimetry can help you with your research. Automated Isothermal Titration Calorimeter (Auto ITC): ITC is the standard for measuring biomolecular interactions. ITC is a thermodynamic technique that directly measures the heat released or absorbed during the biomolecular binding event. Measurement of this heat allows accurate determination of binding constants(KB), reaction stoichiometry(n), enthalpy (delta H) and entropy(delta S), thereby providing a complete thermodynamic profile of the molecular interaction in a single experiment. Differential Scanning Calorimeter (DSC): DSC is used to study stability of biological systems. It measures the enthalpy (delta H) of unfolding due to heat denaturation. The higher the thermal transition midpoint (Tm) when 50% of the biomolecules are unfolded the more stable the molecule. DSC is also used to determine the change in heat capacity (delta Cp) of denaturation.
Contact
Julia Fecko
jaf48@psu.edu
814-865-8068