News

New tool reveals DNA structures that influence disease

Disruption of certain DNA structures — called topologically associating domains, or TADs — is linked with the development of disease, including some cancers. With its newly created algorithm that quickly locates and helps elucidate the complex functions of TADs, an international team of researchers is making it easier to study these important structures and help prevent disease.

Respiration key to increase oxygen in the brain

Contrary to accepted knowledge, blood can bring more oxygen to mice brains when they exercise because the increased respiration packs more oxygen into the hemoglobin, according to an international team of researchers who believe that this holds true for all mammals.

Tracking inheritance of human mitochondrial DNA

New insight into how genetic information stored in human mitochondria is passed from one generation to the next could have important implications for genetic counseling of people planning pregnancies, according to a study by researchers at Penn State and the University of California, Berkeley.

Malaria parasite lives on the edge

The parasite that causes malaria expresses genes that code for the proteins it will need in later life stages, using two separate schemes to prevent these proteins from actually being made until they are needed, according to new research.

Empowering drug discovery by evaluating antivirals in thousands of single cells

A new enhancement to a lab-on-a-chip device allows researchers to simultaneously observe thousands of individual cells that are infected with a virus, providing important information about infection dynamics not available using traditional methods.

One avocado a day helps lower 'bad' cholesterol for heart healthy benefits

Move over, apples — new research from Penn State suggests that eating one avocado a day may help keep “bad cholesterol” at bay. According to the researchers, bad cholesterol can refer to both oxidized low-density lipoprotein (LDL) and small, dense LDL particles.

Paper by MCIBS Grad Laura Bennett Inspires Journal Cover

Laura Bennett's investigation into the effects of inflammation, done with advisor Robert Paulson, was featured on the cover of Science Signaling last month.

Melissa Rolls appointed Paul Berg Professor of Biochemistry

Melissa Rolls, professor of biochemistry and molecular biology, has been named the Paul Berg Professor of Biochemistry. The professorship was created in 1995 by an anonymous donor in honor of Paul Berg, a 1948 Penn State graduate who was named a Distinguished Alumnus in 1974 and earned the Nobel Prize in 1980 for developing a method to map the structure and function of DNA.

Penn State researchers receive grant to explore novel method of anticoagulation

Two Penn State biomedical engineering faculty members have received a two-year, $200,000 grant from the American Heart Association (AHA) to explore potential solutions to thrombosis, or blood clot formation, a prevalent issue with blood-contacting medical devices such as heart valves, blood pumps and cardiac stents.

Virus may jump species through 'rock-and-roll' motion with receptors

Like a janitor thumbing through a keychain to find just the right key to open a lock, the "rock-and-roll" motion of the canine parvovirus during the binding process may help explain how the virus can find the spot on a receptor to infect not just dogs, but multiple species, according to an international team of researchers.