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Yongsoo Kim, associate professor of neural and behavioral sciences at the Penn State College of Medicine, is leading a new five-year, $17.9 million grant from the National Institutes of Health's National Institute of Mental Health. Credit: Jason Plotkin / Penn State. Creative Commons

$17.9M NIH grant to research neurodevelopment disorders

Illuminating key biological pathways that underlie neurodevelopmental and psychiatric disorders, such as autism spectrum disorder and attention deficit hyperactivity disorder, is the goal of a new five-year, $17.9 million grant from the National Institutes of Health’s National Institute of Mental Health to a national team of researchers.

Christina Grozinger was appointed the new director of the Huck Institutes of the Life Sciences at Penn State. Credit: Christina Grozinger / Penn State. Creative Commons

Christina Grozinger to lead Huck Institutes of the Life Sciences as director

Christina Grozinger, Publius Vergilius Maro Professor of Entomology and director of the Center for Pollinator Research, has been named the new director of the Huck Institutes of the Life Sciences at Penn State.

Through a series of experiments, the research team led by Scott Medina, right, William and Wendy Korb Early Career Professor of Biomedical Engineering at Penn State, replaced the water-based solution commonly used in protein-based medications with a perfluorocarbon oil and tested five different proteins with a range of health-related functions such as antibodies and enzymes. Credit: Penn State. Creative Commons

Discovery could eliminate need to refrigerate vaccines and protein-based drugs

A new storage technique can keep protein-based drugs and vaccines stable without keeping them cold. The discovery, led by researchers at Penn State, could eliminate the need for refrigeration for hundreds of life-saving medicines like insulin, monoclonal antibodies and viral vaccines.

The study focused on the horned-face bee, which helps pollinate crops like apples and blueberries, and the alfalfa leafcutting bee, which pollinates alfalfa. Credit: Alain C./Flickr. All Rights Reserved.

Quantity over quality? Different bees are attracted to different floral traits

When it comes to deciding where they’re going to get their next meal, different species of bees may be attracted to different flower traits, according to a study led by researchers at Penn State and published in PNAS Nexus.

The Penn State Neuroscience community kicked off their 2024-25 seminar series with presentations by the second-year doctoral students in the Huck Neuroscience Program. The 2024 Big 10 Neuroscience Annual Meeting will provide similar events for student presentations and networking and will feature presentations from all career stages. Credit: Dan Levy and Keith Hickey/Huck Institutes. All Rights Reserved.

Fourth annual Big Ten Neuroscience Symposium to convene at Penn State

The Penn State Neuroscience Institute, through the Huck Institutes of the Life Sciences and the Penn State College of Medicine, will host the Big Ten Neuroscience Annual Meeting on July 21 and 22 at the Nittany Lion Inn in State College.

Salmonella infections in dogs may be an overlooked transmission vector to humans, researchers reported in a new study.  Credit: SeventyFour/Getty Images. All Rights Reserved.

Pet dogs often overlooked as spreader of antimicrobial-resistant Salmonella

A team of Penn State researchers have found that household dogs are an overlooked transmission point for zoonotic pathogens such as nontyphoidal Salmonella.

A led by Penn State researchers compared two treatments for a common uterine infection, called clinical metritis, that can lead to serious health problems for dairy cows. One treatment was based on antibiotics and the other was not. Both treatments had a similar clinical cure rate in mild cases of the disease. Credit: Penn State. Creative Commons

New treatment for dairy cows could help fight antibiotic resistance, study finds

A concentrated sugar solution could be just as effective as antibiotics at treating a common infection in dairy cows, according to a new study led by researchers at Penn State.

New research finds sex-specific regions of the brain can relieve the detrimental effects of chronic stress in male and female mice. Left: Schematic showing a cortical microcircuit with three types of interneurons expressing somatostatin (SST), parvalbumin (PV) or vasointestinal peptide (VIP) and their distinct patterns of innervation of glutamatergic output neurons (PNs), with thin lines representing axons that send chemical signals and the thicker lines of PNs representing dendrites that receive information. There is selective innervation of the distal ends of PN dendrites by axons of SST neurons. Right: Increased activity of SST neurons by genetically induced disinhibition, on top right, or by chemogenetic activation of SST neurons in the medial prefrontal cortex, on bottom right, leads to stress resilience and facilitates the reversal of the detrimental behavioral effects of stress exposure in male but not female mice. Credit: Bernhard Lüscher / Penn State. Creative Commons

Brain regions that relieve effects of chronic stress in mice differ based on sex

In two new studies, researchers made mice resilient to stress by activating neurons in different brain regions and found that the changes involved are highly sex-specific

Relieving chronic stress in the brains of male and female mice

In two new studies, researchers made mice resilient to stress by activating neurons in different brain regions and show that the brain regions and gene expression changes involved are highly sex-specific.

Through studies on rats, a team of researchers at Penn State has pinpointed the exact moment of loss of consciousness due to anesthesia, mapping what happens in different brain regions during that moment.   Credit: Provided by Nanyin Zhang . All Rights Reserved.

Brain mechanisms underpinning loss of consciousness identified

Rapid activity in three brain regions appears to trigger loss of consciousness, researchers at Penn State find.