Bioinformatics And Genomics News | Bioinformatics and Genomics

May 02, 2019

NIH Grant Funds Research to Pinpoint Natural Selection’s Influence on Genomes

With a $1.7 million grant through the National Institutes of Health, researchers led by Michael DeGiorgio will begin to tease apart individual forces to understand how much influence natural selection has had on our evolutionary path.

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Apr 19, 2019

NIH Trainees Juan Cerda and Catherine Douds Receive NSF-GRFP Honorable Mentions

Juan Cerda and Catherine Douds, both members of NIH-sponsored training programs overseen by the Huck Institutes, were recognized for their promising research ideas.

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Apr 04, 2019

Insect-deterring sorghum compounds may be eco-friendly pesticide

Compounds produced by sorghum plants to defend against insect feeding could be isolated, synthesized and used as a targeted, nontoxic insect deterrent, according to researchers who studied plant-insect interactions that included field, greenhouse and laboratory components.

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Apr 03, 2019

Michael Axtell Among Five Receiving Faculty Scholar Medals

Five Penn State faculty members have received 2019 Faculty Scholar Medals for Outstanding Achievement for excellence in scholarship, research and the arts.

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Apr 03, 2019

Guiltinan, Maximova receive the 2019 Kopp International Achievement Award

Mark Guiltinan, professor of plant molecular biology, and Siela Maximova, research professor of plant biotechnology, both in the College of Agricultural Sciences, are the recipients of Penn State's 2019 W. LaMarr Kopp International Achievement Award.

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Molly Hall, assistant professor of veterinary and biomedical sciences. IMAGE: MOLLY HALL

Apr 10, 2019

Hall, Brent to receive Roy C. Buck awards during annual celebration

Two faculty members in Penn State’s College of Agricultural Sciences have been named the recipients of the 2018 Roy C. Buck Faculty Award, which recognizes exceptional articles accepted or published by refereed scholarly journals in the social and human sciences within the past two years.

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Mar 26, 2019

CBIOS Trainee Hillary Koch Awarded NIH Fellowship

Koch's dissertation proposal, "Statistical Methods for Differential Peak Detection in Hi-C Data," was funded upon its first submission to the National Human Genome Research Institute.

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In this image, a protein (blue and black) is beginning to make its long (molecularly speaking) journey from the ribosome (red and yellow) through the tube and toward its eventual folding. IMAGE: PENN STATE

Mar 06, 2019

Researchers find features that shape mechanical force during protein synthesis

Like any assembly line, the body’s protein-building process generates a mechanical force as it produces these important cellular building blocks. Now, a team of researchers suggest they are one step closer to understanding that force. They also built a mathematical model to help guide scientists with future investigations into how the body creates proteins

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Dr. Melissa Rolls with current and prospective graduate students

Jan 25, 2019

Prospective Grad Students Get A Taste of Life at Penn State

Students interested in the Bioinformatics and Genomics; Plant Biology; Neuroscience; and Molecular, Cellular, and Integrative Biosciences graduate programs were given a warm welcome on a snowy weekend.

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Differences in geographic origin of a person’s mitochondrial and nuclear genomes due to admixture can affect function of mitochondria, energy-generating organelles located inside cells that have their own separate genome. A new study reveals that mitochondrial DNA (mtDNA) copy number decreases with increasing “mito-nuclear” dissimilarity in geographic origins of the mitochondrial and nuclear genomes (e.g. as the proportion of nuclear DNA from population 1 decrease). IMAGE: ARSLAN ZAIDI, PENN STATE

Jan 15, 2019

Differences in genes’ geographic origin influence mitochondrial function

Differences in the geographic origin of genes may affect the function of human mitochondria — energy-generating organelles inside of cells — according to a new study. Mitochondria have their own genome, separate from the nuclear genome contained in the nucleus of the cell, and both genomes harbor genes integral to energy production by mitochondria. The study explores whether these “mito-nuclear” interactions, which are fine-tuned by natural selection over deep evolutionary time, could be altered when genes of different geographic origins are brought together within a genome.

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