Skeleton ‘gatekeeper’ lining brain cells could guard against Alzheimer’s
Brain cells are constantly swallowing material from the fluid that surrounds them — signaling molecules, nutrients, even pieces of their own surfaces — in a process known as endocytosis that is essential for learning, memory and basic neural upkeep. New research by Penn State scientists has revealed this vital process may be governed by a previously unknown molecular gatekeeper: a lattice‑like structure just beneath the surface of neurons called the membrane‑associated periodic skeleton.