Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research

Scott Lindner

Research Summary

Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Huck Graduate Students

Huck Affiliations


Publication Tags

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Parasites Malaria Proteins Plasmodium Sporozoites Liver Proteomics Salivary Glands Plasmodium Vivax Rna Binding Proteins Proteome Genes Plasmodium Falciparum Infections Plasmodium Yoelii Clustered Regularly Interspaced Short Palindromic Repeats Messenger Rna Infection Protein Antimalarials Antimalarial Membrane Proteins Membranes Transcriptome Mass Spectrometry

Most Recent Publications

Hui Min, Xiaoying Liang, Chengqi Wang, Junling Qin, Rachasak Boonhok, Azhar Muneer, Awtum M. Brashear, Xiaolian Li, Allen M. Minns, Swamy Rakesh Adapa, Rays H.Y. Jiang, Gang Ning, Yaming Cao, Scott E. Lindner, Jun Miao, Liwang Cui, 2024, Nature Communications

CD4 T Cell–Derived IL-21 Is Critical for Sustaining Plasmodium Infection–Induced Germinal Center Responses and Promoting the Selection of Memory B Cells with Recall Potential

Jordan T. Johnson, Fionna A. Surette, Graham R. Ausdal, Manan Shah, Allen M. Minns, Scott E. Lindner, Ryan A. Zander, Noah S. Butler, 2024, Journal of Immunology on p. 1467-1478

Devanshi R. Patel, Allen M. Minns, Derek G. Sim, Cassandra J. Field, Abigail E. Kerr, Talia A. Heinly, Erin H. Luley, Randall M. Rossi, Carol M. Bator, Ibrahim M. Moustafa, Elizabeth B. Norton, Susan L. Hafenstein, Scott E. Lindner, Troy C. Sutton, 2024, Microbiology spectrum

Mitchell J. Godin, Aswathy Sebastian, Istvan Albert, Scott E. Lindner, 2023, Journal of Biological Chemistry

James P. McGee, Jean Paul Armache, Scott E. Lindner, 2023, PLoS Pathogens

Juliane Sassmannshausen, Sandra Bennink, Ute Distler, Juliane Küchenhoff, Allen M. Minns, Scott E. Lindner, Paul Christian Burda, Stefan Tenzer, Tim W. Gilberger, Gabriele Pradel, 2023, Molecular Microbiology

Rebecca L. Clements, Alexander A. Morano, Francesca M. Navarro, James P. McGee, Esrah W. Du, Vincent A. Streva, Scott E. Lindner, Jeffrey D. Dvorin, 2022, Proceedings of the National Academy of Sciences of the United States of America

Ian M. Lamb, Kelly T. Rios, Anurag Shukla, Avantika I. Ahiya, Joanne Morrisey, Joshua C. Mell, Scott E. Lindner, Michael W. Mather, Akhil B. Vaidya, 2022, PLoS One

Camila Marques-da-Silva, Kristen Peissig, Michael P. Walker, Justine Shiau, Carson Bowers, Dennis E. Kyle, Rahul Vijay, Scott E. Lindner, Samarchith P. Kurup, 2022, Cell Reports

Kelly T. Rios, Taylor M. Dickson, Scott E. Lindner, 2022, mSphere

Most-Cited Papers

Sebastian A. Mikolajczak, Ashley M. Vaughan, Niwat Kangwanrangsan, Wanlapa Roobsoong, Matthew Fishbaugher, Narathatai Yimamnuaychok, Nastaran Rezakhani, Viswanathan Lakshmanan, Naresh Singh, Alexis Kaushansky, Nelly Camargo, Michael Baldwin, Scott E. Lindner, John H. Adams, Jetsumon Sattabongkot, Stefan H.I. Kappe, 2015, Cell Host and Microbe on p. 526-535

Kristian E. Swearingen, Scott E. Lindner, Lirong Shi, Melanie J. Shears, Anke Harupa, Christine S. Hopp, Ashley M. Vaughan, Timothy A. Springer, Robert L. Moritz, Stefan H.I. Kappe, Photini Sinnis, 2016, PLoS Pathogens

Scott E. Lindner, Kristian E. Swearingen, Melanie J. Shears, Michael P. Walker, Erin N. Vrana, Kevin J. Hart, Allen M. Minns, Photini Sinnis, Robert L. Moritz, Stefan H.I. Kappe, 2019, Nature Communications

Kristian E. Swearingen, Scott E. Lindner, Erika L. Flannery, Ashley M. Vaughan, Robert D. Morrison, Rapatbhorn Patrapuvich, Cristian Koepfli, Ivo Muller, Aaron Jex, Robert L. Moritz, Stefan H.I. Kappe, Jetsumon Sattabongkot, Sebastian A. Mikolajczak, 2017, PLoS Neglected Tropical Diseases

BP Niranjan Reddy, Sony Shrestha, Kevin J. Hart, Xiaoying Liang, Karen Kemirembe, Liwang Cui, Scott E. Lindner, 2015, BMC Genomics

Liwang Cui, Scott Lindner, Jun Miao, 2015, Annals of the New York Academy of Sciences on p. 1-9

Ryan A. Zander, Rahul Vijay, Angela D. Pack, Jenna J. Guthmiller, Amy C. Graham, Scott E. Lindner, Ashley M. Vaughan, Stefan H.I. Kappe, Noah S. Butler, 2017, Cell Reports on p. 1839-1852

Scott E. Lindner, Mark J. Sartain, Kiera Hayes, Anke Harupa, Robert L. Moritz, Stefan H.I. Kappe, Ashley M. Vaughan, 2014, Molecular Microbiology on p. 679-693

Marcus C.S. Lee, Scott E. Lindner, Jose Juan Lopez-Rubio, Manuel Llinás, 2019, Briefings in Functional Genomics and Proteomics on p. 281-289

Ivo Muller, Aaron R. Jex, Stefan H.I. Kappe, Sebastian A. Mikolajczak, Jetsumon Sattabongkot, Rapatbhorn Patrapuvich, Scott Lindner, Erika L. Flannery, Cristian Koepfli, Brendan Ansell, Anita Lerch, Samantha J. Emery-Corbin, Sarah Charnaud, Jeffrey Smith, Nicolas Merrienne, Kristian E. Swearingen, Robert L. Moritz, Michaela Petter, Michael F. Duffy, Vorada Chuenchob, 2019, International Journal for Parasitology on p. 501-513

News Articles Featuring Scott Lindner

Huck Leadership Fellows selected for 2024-25

For the 2024-2025 academic year, Huck Institutes of the Life Sciences has appointed Associate Professor of Biomedical Engineering Scott Medina, Professor of Statistics Lingzhou Xue, and Associate Professor of Surgery Dino Ravnic to be Huck Leadership Fellows.

New nasal vaccine platform helps clear COVID-19 infections in an animal model

A newly developed intranasal vaccine candidate helps to clear COVID-19 infections more quickly than controls in pre-clinical testing, according to a recent study.

Neela Yennawar and Scott Lindner selected as 2023 Huck Leadership Fellows

Launched in 2022, the Huck Leadership Fellows Program was developed for faculty members seeking to sharpen their leadership skills with an opportunity for exposure to senior leadership within the interdisciplinary research unit.

Study finds short window for donating convalescent plasma to COVID-19 patients

The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency-use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new Penn State-led study.

Study finds short window for donating convalescent plasma to COVID-19 patients

The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new study. The research also reveals that the ideal convalescent plasma donor is a recovered COVID-19 patient who is older than 30 and whose illness had been severe.

Malaria parasite lives on the edge

The parasite that causes malaria expresses genes that code for the proteins it will need in later life stages, using two separate schemes to prevent these proteins from actually being made until they are needed, according to new research.

Male birth control for the malaria parasite