Scott Lindner

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research

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Most Recent Papers

Protein-RNA interactions important for Plasmodium transmission

Kelly T. Rios, Scott E. Lindner, 2019, PLoS pathogens on p. e1008095

Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

Scott E. Lindner, Kristian E. Swearingen, Melanie J. Shears, Michael P. Walker, Erin N. Vrana, Kevin J. Hart, Allen M. Minns, Photini Sinnis, Robert L. Moritz, Stefan H.I. Kappe, 2019, Nature communications

Cutting back malaria

Marcus C.S. Lee, Scott E. Lindner, Jose Juan Lopez-Rubio, Manuel Llinás, 2019, Briefings in functional genomics on p. 281-289

Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and mechanisms for liver-stage differentiation in relapsing malaria

Ivo Muller, Aaron R. Jex, Stefan H.I. Kappe, Sebastian A. Mikolajczak, Jetsumon Sattabongkot, Rapatbhorn Patrapuvich, Scott Eugene Lindner, Erika L. Flannery, Cristian Koepfli, Brendan Ansell, Anita Lerch, Samantha J. Emery-Corbin, Sarah Charnaud, Jeffrey Smith, Nicolas Merrienne, Kristian E. Swearingen, Robert L. Moritz, Michaela Petter, Michael F. Duffy, Vorada Chuenchob, 2019, International Journal for Parasitology on p. 501-513

Plasmodium male gametocyte development and transmission are critically regulated by the two putative deadenylases of the CAF1/CCR4/NOT complex

Kevin J. Hart, Jenna Oberstaller, Michael P. Walker, Allen M. Minns, Mark F. Kennedy, Ian Padykula, John H. Adams, Scott E. Lindner, 2019, PLoS pathogens

Ribozyme-mediated, multiplex CRISPR gene editing and CRISPR interference (CRISPRi) in rodent-infectious Plasmodium yoelii

Michael P. Walker, Scott Eugene Lindner, 2019, Journal of Biological Chemistry on p. 9555-9566

Plasmodium Parasites Viewed through Proteomics

Kristian E. Swearingen, Scott E. Lindner, 2018, Trends in Parasitology

Th1-like Plasmodium-Specific Memory CD4<sup>+</sup> T Cells Support Humoral Immunity

Ryan A. Zander, Rahul Vijay, Angela D. Pack, Jenna J. Guthmiller, Amy C. Graham, Scott Eugene Lindner, Ashley M. Vaughan, Stefan H.I. Kappe, Noah S. Butler, 2018, Cell Reports

Nuclear, cytosolic, and surface-localized poly(A)-binding proteins of Plasmodium yoelii

Allen M. Minns, Kevin J. Hart, Suriyasri Subramanian, Susan Hafenstein, Scott E. Lindner, 2018, mSphere

5-Aminopyrazole-4-carboxamide analogues are selective inhibitors of Plasmodium falciparum microgametocyte exflagellation and potential malaria transmission blocking agents

Wenlin Huang, Matthew A. Hulverson, Zhongsheng Zhang, Ryan Choi, Kevin J. Hart, Mark Kennedy, Rama Subba Rao Vidadala, Dustin J. Maly, Wesley C. Van Voorhis, Scott E. Lindner, Erkang Fan, Kayode K. Ojo, 2016, Bioorganic and Medicinal Chemistry Letters on p. 5487-5491

Recent Most-Cited Papers

Total and putative surface proteomics of malaria parasite salivary gland sporozoites

Scott E. Lindner, Kristian E. Swearingen, Anke Harupa, Ashley M. Vaughan, Photini Sinnis, Robert L. Moritz, Stefan H.I. Kappe, 2013, Molecular and Cellular Proteomics on p. 1127-1143

Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice

Sebastian A. Mikolajczak, Ashley M. Vaughan, Niwat Kangwanrangsan, Wanlapa Roobsoong, Matthew Fishbaugher, Narathatai Yimamnuaychok, Nastaran Rezakhani, Viswanathan Lakshmanan, Naresh Singh, Alexis Kaushansky, Nelly Camargo, Michael Baldwin, Scott E. Lindner, John H. Adams, Jetsumon Sattabongkot, Stefan H.I. Kappe, 2015, Cell Host and Microbe on p. 526-535

A rapid and scalable density gradient purification method for Plasmodium sporozoites

Mark Kennedy, Matthew E. Fishbaugher, Ashley M. Vaughan, Rapatbhorn Patrapuvich, Rachasak Boonhok, Narathatai Yimamnuaychok, Nastaran Rezakhani, Peter Metzger, Marisa Ponpuak, Jetsumon Sattabongkot, Stefan H. Kappe, Jen Cc Hume, Scott E. Lindner, 2012, Malaria journal

Structural Determinants of DNA Binding by a P. falciparum ApiAP2 Transcriptional Regulator

Scott Eugene Lindner, Erandi K. De Silva, James L. Keck, Manuel Llinas, 2010, Journal of Molecular Biology on p. 558-567

Perturbations of PlasmodiumPuf2 expression and RNA-seq of Puf2-deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite transmissibility

Scott Eugene Lindner, Sebastian A. Mikolajczak, Ashley M. Vaughan, Wonjong Moon, Brad R. Joyce, William J. Sullivan, Stefan H I Kappe, 2013, Cellular Microbiology on p. 1266-1283

A transgenic Plasmodium falciparum NF54 strain that expresses GFP-luciferase throughout the parasite life cycle

Ashley M. Vaughan, Sebastian A. Mikolajczak, Nelly Camargo, Viswanathan Lakshmanan, Mark Kennedy, Scott Eugene Lindner, Jessica L. Miller, Jen C.C. Hume, Stefan H.I. Kappe, 2012, Molecular and biochemical parasitology on p. 143-147

Translational regulation during stage transitions in malaria parasites

Liwang Cui, Scott Eugene Lindner, Jun Miao, 2015, Annals of the New York Academy of Sciences on p. 1-9

A bioinformatic survey of RNA-binding proteins in Plasmodium

BP Niranjan Reddy, Sony Shrestha, Kevin J. Hart, Xiaoying Liang, Karen Kemirembe, Liwang Cui, Scott E. Lindner, 2015, BMC genomics

A nondiscriminating glutamyl-tRNA synthetase in the plasmodium apicoplast

Boniface M. Mailu, Gowthaman Ramasamay, Devaraja G. Mudeppa, Ling Li, Scott E. Lindner, Megan J. Peterson, Amy E. DeRocher, Stefan H.I. Kappe, Pradipsinh K. Rathod, Malcolm J. Gardner, 2013, Journal of Biological Chemistry on p. 32539-32552

Plasmodium yoelii inhibitor of cysteine proteases is exported to exomembrane structures and interacts with yoelipain-2 during asexual blood-stage development

Ying Pei, Jessica L. Miller, Scott E. Lindner, Ashley M. Vaughan, Motomi Torii, Stefan H.I. Kappe, 2013, Cellular Microbiology on p. 1508-1526