Neela Yennawar
Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities
- 0088 Althouse Lab
University Park, PA 16802 - nhy1@psu.edu
- 814-863-9387
Research Summary
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.
Huck Institutes Affiliations
Most Recent Papers
Molecular Mechanism for Folding Cooperativity of Functional RNAs in Living Organisms
Kathleen A. Leamy, Neela H. Yennawar, Philip C. Bevilacqua, 2018, Biochemistry on p. 2994-3002
Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA
Michael DiMarzio, Brigida Rusconi, Neela H. Yennawar, Mark Eppinger, Andrew D. Patterson, Edward G. Dudley, 2017, PloS one
Cooperative RNA Folding under Cellular Conditions Arises from Both Tertiary Structure Stabilization and Secondary Structure Destabilization
Kathleen A. Leamy, Neela H. Yennawar, Philip C. Bevilacqua, 2017, Biochemistry on p. 3422-3433
The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme
Jamie L. Bingaman, Sixue Zhang, David R. Stevens, Neela H. Yennawar, Sharon Hammes-Schiffer, Philip C. Bevilacqua, 2017, Nature Chemical Biology on p. 439-445
Inhibition of pancreatic lipase by black tea theaflavins
Shannon L. Glisan, Kimberly A. Grove, Neela H. Yennawar, Joshua D. Lambert, 2017, Food Chemistry on p. 296-300
Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid
Olga A. Esakova, Alexey Silakov, Tyler L. Grove, Allison H. Saunders, Martin I. McLaughlin, Neela H. Yennawar, Squire J. Booker, 2016, Journal of the American Chemical Society on p. 7224-7227
Structural and Biochemical Characterizations of Methanoredoxin from Methanosarcina acetivorans, a Glutaredoxin-Like Enzyme with Coenzyme M-Dependent Protein Disulfide Reductase Activity
Deepa Yenugudhati, Divya Prakash, Adepu K. Kumar, R. Siva Sai Kumar, Neela H. Yennawar, Hemant P. Yennawar, James G. Ferry, 2016, Biochemistry on p. 313-321
A High-Throughput Biological Calorimetry Core
Neela H. Yennawar, Julia A. Fecko, Scott A. Showalter, Philip C. Bevilacqua, 2016, Methods in Enzymology on p. 435-460
Conformational ensemble of the poliovirus 3CD precursor observed by MD simulations and confirmed by SAXS
Ibrahim M. Moustafa, David W. Gohara, Akira Uchida, Neela Yennawar, Craig E. Cameron, 2015, Viruses on p. 5962-5986
Structural models of mammalian mitochondrial transcription factor B2
Ibrahim M. Moustafa, Akira Uchida, Yao Wang, Neela Yennawar, Craig E. Cameron, 2015, Biochimica et Biophysica Acta - Gene Regulatory Mechanisms on p. 987-1002
High-Impact Papers
Structural basis for methyl transfer by a radical SAM enzyme
Amie K. Boal, Tyler L. Grove, Monica I. McLaughlin, Neela H. Yennawar, Squire J. Booker, Amy C. Rosenzweig, 2011, Science on p. 1089-1092
Structural basis for entropy-driven cellulose binding by a type-A cellulose-binding module (CBM) and bacterial expansin
Nikolaos Georgelis, Neela H. Yennawar, Daniel J. Cosgrove, 2012, Proceedings of the National Academy of Sciences of the United States of America on p. 14830-14835
Molecular crowding favors reactivity of a human ribozyme under physiological ionic conditions
Christopher A. Strulson, Neela H. Yennawar, Robert P. Rambo, Philip C. Bevilacqua, 2013, Biochemistry on p. 8187-8197
Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves
Feng Guo, Weijie Zhou, Peng Li, Zhangming Mao, Neela H. Yennawar, Jarrod B. French, Tony Jun Huang, 2015, Small on p. 2733-2737
Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases
Bigna Wörsdörfer, Mahesh Lingaraju, Neela H. Yennawar, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, Maria Eirini Pandelia, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 18874-18879
The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme
Jamie L. Bingaman, Sixue Zhang, David R. Stevens, Neela H. Yennawar, Sharon Hammes-Schiffer, Philip C. Bevilacqua, 2017, Nature Chemical Biology on p. 439-445
Inhibition of pancreatic lipase by black tea theaflavins
Shannon L. Glisan, Kimberly A. Grove, Neela H. Yennawar, Joshua D. Lambert, 2017, Food Chemistry on p. 296-300
Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae
Jeeyeon Lee, Neela H. Yennawar, Jongsik Gam, Stephen J. Benkovic, 2010, Biochemistry on p. 195-206
X-ray crystal structure and small-angle X-ray scattering of sheep liver sorbitol dehydrogenase
Hemant Yennawar, Magda Mller, Richard Gillilan, Neela Yennawar, 2011, Acta Crystallographica Section D: Biological Crystallography on p. 440-446
Cooperative RNA Folding under Cellular Conditions Arises from Both Tertiary Structure Stabilization and Secondary Structure Destabilization
Kathleen A. Leamy, Neela H. Yennawar, Philip C. Bevilacqua, 2017, Biochemistry on p. 3422-3433