Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities

Neela Yennawar

Research Summary

Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Huck Institutes Affiliations

Publication Tags

Proteins Rna Enzymes X Rays Transfer Rna Tea Lipase Theaflavin Catalytic Rna Temperature Amino Acids Ions Choloylglycine Hydrolase Hot Temperature X Ray Crystallography Rna Folding Genes Calorimetry Crystallography Glucosamine 6 Phosphate Sonication Tetrahydrofolate Dehydrogenase Theaflavins Disulfides Lactobacillus Johnsonii

Most Recent Papers

Molecular Mechanism for Folding Cooperativity of Functional RNAs in Living Organisms

Kathleen A. Leamy, Neela H. Yennawar, Philip C. Bevilacqua, 2018, Biochemistry on p. 2994-3002

Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA

Michael DiMarzio, Brigida Rusconi, Neela H. Yennawar, Mark Eppinger, Andrew D. Patterson, Edward G. Dudley, 2017, PloS one

Cooperative RNA Folding under Cellular Conditions Arises from Both Tertiary Structure Stabilization and Secondary Structure Destabilization

Kathleen A. Leamy, Neela H. Yennawar, Philip C. Bevilacqua, 2017, Biochemistry on p. 3422-3433

The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme

Jamie L. Bingaman, Sixue Zhang, David R. Stevens, Neela H. Yennawar, Sharon Hammes-Schiffer, Philip C. Bevilacqua, 2017, Nature Chemical Biology on p. 439-445

Inhibition of pancreatic lipase by black tea theaflavins

Shannon L. Glisan, Kimberly A. Grove, Neela H. Yennawar, Joshua D. Lambert, 2017, Food Chemistry on p. 296-300

Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid

Olga A. Esakova, Alexey Silakov, Tyler L. Grove, Allison H. Saunders, Martin I. McLaughlin, Neela H. Yennawar, Squire J. Booker, 2016, Journal of the American Chemical Society on p. 7224-7227

Structural and Biochemical Characterizations of Methanoredoxin from Methanosarcina acetivorans, a Glutaredoxin-Like Enzyme with Coenzyme M-Dependent Protein Disulfide Reductase Activity

Deepa Yenugudhati, Divya Prakash, Adepu K. Kumar, R. Siva Sai Kumar, Neela H. Yennawar, Hemant P. Yennawar, James G. Ferry, 2016, Biochemistry on p. 313-321

A High-Throughput Biological Calorimetry Core

Neela H. Yennawar, Julia A. Fecko, Scott A. Showalter, Philip C. Bevilacqua, 2016, Methods in Enzymology on p. 435-460

Conformational ensemble of the poliovirus 3CD precursor observed by MD simulations and confirmed by SAXS

Ibrahim M. Moustafa, David W. Gohara, Akira Uchida, Neela Yennawar, Craig E. Cameron, 2015, Viruses on p. 5962-5986

Structural models of mammalian mitochondrial transcription factor B2

Ibrahim M. Moustafa, Akira Uchida, Yao Wang, Neela Yennawar, Craig E. Cameron, 2015, Biochimica et Biophysica Acta - Gene Regulatory Mechanisms on p. 987-1002

High-Impact Papers

Structural basis for methyl transfer by a radical SAM enzyme

Amie K. Boal, Tyler L. Grove, Monica I. McLaughlin, Neela H. Yennawar, Squire J. Booker, Amy C. Rosenzweig, 2011, Science on p. 1089-1092

Structural basis for entropy-driven cellulose binding by a type-A cellulose-binding module (CBM) and bacterial expansin

Nikolaos Georgelis, Neela H. Yennawar, Daniel J. Cosgrove, 2012, Proceedings of the National Academy of Sciences of the United States of America on p. 14830-14835

Molecular crowding favors reactivity of a human ribozyme under physiological ionic conditions

Christopher A. Strulson, Neela H. Yennawar, Robert P. Rambo, Philip C. Bevilacqua, 2013, Biochemistry on p. 8187-8197

Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves

Feng Guo, Weijie Zhou, Peng Li, Zhangming Mao, Neela H. Yennawar, Jarrod B. French, Tony Jun Huang, 2015, Small on p. 2733-2737

Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases

Bigna Wörsdörfer, Mahesh Lingaraju, Neela H. Yennawar, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, Maria Eirini Pandelia, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 18874-18879

The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme

Jamie L. Bingaman, Sixue Zhang, David R. Stevens, Neela H. Yennawar, Sharon Hammes-Schiffer, Philip C. Bevilacqua, 2017, Nature Chemical Biology on p. 439-445

Inhibition of pancreatic lipase by black tea theaflavins

Shannon L. Glisan, Kimberly A. Grove, Neela H. Yennawar, Joshua D. Lambert, 2017, Food Chemistry on p. 296-300

Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae

Jeeyeon Lee, Neela H. Yennawar, Jongsik Gam, Stephen J. Benkovic, 2010, Biochemistry on p. 195-206

X-ray crystal structure and small-angle X-ray scattering of sheep liver sorbitol dehydrogenase

Hemant Yennawar, Magda Mller, Richard Gillilan, Neela Yennawar, 2011, Acta Crystallographica Section D: Biological Crystallography on p. 440-446

Cooperative RNA Folding under Cellular Conditions Arises from Both Tertiary Structure Stabilization and Secondary Structure Destabilization

Kathleen A. Leamy, Neela H. Yennawar, Philip C. Bevilacqua, 2017, Biochemistry on p. 3422-3433