Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities

Neela Yennawar

Research Summary

Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Huck Affiliations

Publication Tags

Rna Enzymes Choloylglycine Hydrolase Transfer Rna Lactobacillus Johnsonii Proteins Genes Temperature Hot Temperature Rna, Transfer, Phe Ribonucleotide Reductases X Rays Rna Folding In Vitro Techniques Catalytic Domain Substrate Specificity Lactobacillus Mice Stabilization Receptors Mycothiol S Conjugate Amidase Biosynthesis Catalytic Rna Antagonists Nucleotides

Most Recent Papers

Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis

Hannah R. Rose, Ailiena O. Maggiolo, Molly J. McBride, Gavin M. Palowitch, Maria Eirini Pandelia, Katherine M. Davis, Neela Yennawar, Amie Kathleen Boal, 2019, Biochemistry on p. 1845-1860

Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis

Hannah R. Rose, Ailiena O. Maggiolo, Molly J. McBride, Gavin M. Palowitch, Maria Eirini Pandelia, Katherine M. Davis, Neela Yennawar, Amie Kathleen Boal, 2019, Biochemistry on p. 1845-1860

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

Samuel K. McBrayer, Jared R. Mayers, Gabriel J. DiNatale, Diana D. Shi, Januka Khanal, Abhishek A. Chakraborty, Kristopher A. Sarosiek, Kimberly J. Briggs, Alissa K. Robbins, Tomasz Sewastianik, Sarah J. Shareef, Benjamin A. Olenchock, Seth J. Parker, Kensuke Tateishi, Jessica B. Spinelli, Mirazul Islam, Marcia C. Haigis, Ryan E. Looper, Keith L. Ligon, Bradley E. Bernstein, Ruben D. Carrasco, Daniel P. Cahill, John M. Asara, Christian M. Metallo, Neela Yennawar, Matthew G. Vander Heiden, William G. Kaelin, 2018, Cell on p. 101-116.e25

Molecular Mechanism for Folding Cooperativity of Functional RNAs in Living Organisms

Kathleen A. Leamy, Neela Yennawar, Philip C. Bevilacqua, 2018, Biochemistry on p. 2994-3002

Molecular Mechanism for Folding Cooperativity of Functional RNAs in Living Organisms

Kathleen A. Leamy, Neela Yennawar, Philip C. Bevilacqua, 2018, Biochemistry on p. 2994-3002

Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA

Michael DiMarzio, Brigida Rusconi, Neela Yennawar, Mark Eppinger, Andrew David Patterson, Edward G. Dudley, 2017, PLoS One

Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA

Michael DiMarzio, Brigida Rusconi, Neela Yennawar, Mark Eppinger, Andrew David Patterson, Edward G. Dudley, 2017, PLoS One

Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA

Michael DiMarzio, Brigida Rusconi, Neela Yennawar, Mark Eppinger, Andrew David Patterson, Edward G. Dudley, 2017, PLoS One

Cooperative RNA Folding under Cellular Conditions Arises from Both Tertiary Structure Stabilization and Secondary Structure Destabilization

Kathleen A. Leamy, Neela Yennawar, Philip C. Bevilacqua, 2017, Biochemistry on p. 3422-3433

Cooperative RNA Folding under Cellular Conditions Arises from Both Tertiary Structure Stabilization and Secondary Structure Destabilization

Kathleen A. Leamy, Neela Yennawar, Philip C. Bevilacqua, 2017, Biochemistry on p. 3422-3433

High-Impact Papers

Structural basis for methyl transfer by a radical SAM enzyme

Amie Kathleen Boal, Tyler L. Grove, Monica I. McLaughlin, Neela Yennawar, Squire J. Booker, Amy C. Rosenzweig, 2011, Science on p. 1089-1092

Structural basis for entropy-driven cellulose binding by a type-A cellulose-binding module (CBM) and bacterial expansin

Nikolaos Georgelis, Neela Yennawar, Daniel J. Cosgrove, 2012, Proceedings of the National Academy of Sciences of the United States of America on p. 14830-14835

Molecular crowding favors reactivity of a human ribozyme under physiological ionic conditions

Christopher A. Strulson, Neela Yennawar, Robert P. Rambo, Philip C. Bevilacqua, 2013, Biochemistry on p. 8187-8197

Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves

Feng Guo, Weijie Zhou, Peng Li, Zhangming Mao, Neela Yennawar, Jarrod B. French, Tony Jun Huang, 2015, Small on p. 2733-2737

The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme

Jamie L. Bingaman, Sixue Zhang, David R. Stevens, Neela Yennawar, Sharon Hammes-Schiffer, Philip C. Bevilacqua, 2017, Nature Chemical Biology on p. 439-445

Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases

Bigna Wörsdörfer, Mahesh Lingaraju, Neela Yennawar, Amie Kathleen Boal, Carsten Krebs, Joseph M. Bollinger, Jr., Maria Eirini Pandelia, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 18874-18879

Cooperative RNA Folding under Cellular Conditions Arises from Both Tertiary Structure Stabilization and Secondary Structure Destabilization

Kathleen A. Leamy, Neela Yennawar, Philip C. Bevilacqua, 2017, Biochemistry on p. 3422-3433

Inhibition of pancreatic lipase by black tea theaflavins

Shannon L. Glisan, Kimberly A. Grove, Neela Yennawar, Joshua D. Lambert, 2017, Food Chemistry on p. 296-300

Structural and biochemical characterization of a ferredoxin

Adepu K. Kumar, R. Siva Sai Kumar, Neela Yennawar, Hemant P. Yennawar, James Gregory Ferry, 2015, Biochemistry on p. 3122-3128

X-ray crystal structure and small-angle X-ray scattering of sheep liver sorbitol dehydrogenase

Hemant P. Yennawar, Magda Mller, Richard Gillilan, Neela Yennawar, 2011, Acta Crystallographica Section D: Biological Crystallography on p. 440-446