Joshua Kellogg

Emphasis Area Representative, Molecular Toxicology; Assistant Professor of Veterinary and Biomedical Sciences

Joshua Kellogg

Research Summary

Development of new metabolomics tools for chemical and biological characterization of complex systems. Discovery of new natural products from plants and microorganisms with novel bioactivity against pathogenic fungi and neglected tropical diseases. Bioanalytical techniques to probe the mechanism of action and basic biology of these target organisms. Ethnobotany and indigenous knowledge surrounding plant-based medicine.

Graduate Students

Huck Affiliations

Links

Publication Tags

Metabolomics Mass Spectrometry Medicine Tea Biological Products Hydrastis Liquid Chromatography Camellia Sinensis Metabolites Fractionation Endophytes Xanthoangelol Dietary Supplements Principal Component Analysis Seaweed Lipids Biological Assay Antioxidants Hydrastis Canadensis Climate Change Macrophages Bioassay Flavonoids Adipocytes Datasets

Most Recent Papers

Composite score analysis for unsupervised comparison and network visualization of metabolomics data

Joshua J. Kellogg, Olav M. Kvalheim, Nadja B. Cech, 2020, Analytica Chimica Acta on p. 38-47

Opportunities and Limitations for Untargeted Mass Spectrometry Metabolomics to Identify Biologically Active Constituents in Complex Natural Product Mixtures

Lindsay K. Caesar, Joshua Kellogg, Olav M. Kvalheim, Nadja B. Cech, 2019, Journal of Natural Products on p. 469-484

A random subset implementation of weighted quantile sum (WQS<sub>RS</sub>) regression for analysis of high-dimensional mixtures

Paul Curtin, Joshua Kellogg, Nadja Cech, Chris Gennings, 2019, Communications in Statistics: Simulation and Computation

Detection of adulteration in Hydrastis canadensis (goldenseal) dietary supplements via untargeted mass spectrometry-based metabolomics

Emily D. Wallace, Nicholas H. Oberlies, Nadja B. Cech, Joshua J. Kellogg, 2018, Food and Chemical Toxicology on p. 439-447

Integration of Biochemometrics and Molecular Networking to Identify Antimicrobials in Angelica keiskei

Lindsay K. Caesar, Joshua J. Kellogg, Olav M. Kvalheim, Richard A. Cech, Nadja B. Cech, 2018, Planta Medica on p. 721-728

Identification of intestinal UDP-Glucuronosyltransferase inhibitors in green tea (Camellia sinensis) using a biochemometric approach

Dan Dan Tian, Joshua Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune, Mary F. Paine, 2018, Drug Metabolism and Disposition on p. 552-560

Biochemometrics to Identify Synergists and Additives from Botanical Medicines

Emily R. Britton, Joshua Kellogg, Olav M. Kvalheim, Nadja B. Cech, 2018, Journal of Natural Products on p. 484-493

Conventional and accelerated-solvent extractions of green tea (camellia sinensis) for metabolomics-based chemometrics

Joshua J. Kellogg, Emily D. Wallace, Tyler N. Graf, Nicholas H. Oberlies, Nadja B. Cech, 2017, Journal of Pharmaceutical and Biomedical Analysis on p. 604-610

Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations

Joshua J. Kellogg, Tyler N. Graf, Mary F. Paine, Jeannine S. McCune, Olav M. Kvalheim, Nicholas H. Oberlies, Nadja B. Cech, 2017, Journal of Natural Products on p. 1457-1466

Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis)

Joseph M. Egan, Amninder Kaur, Huzefa A. Raja, Joshua J. Kellogg, Nicholas H. Oberlies, Nadja B. Cech, 2016, Phytochemistry Letters on p. 219-225

Most-Cited Papers

Alaskan wild berry resources and human health under the cloud of climate change

Joshua Kellogg, Jinzhi Wang, Courtney Flint, David Ribnicky, Peter Kuhn, Elvira González De Mejia, Ilya Raskin, Mary Ann Lila, 2010, Journal of agricultural and food chemistry on p. 3884-3900

Biochemometrics for Natural Products Research

Joshua J. Kellogg, Daniel A. Todd, Joseph M. Egan, Huzefa A. Raja, Nicholas H. Oberlies, Olav M. Kvalheim, Nadja B. Cech, 2016, Journal of Natural Products on p. 376-386

Phlorotannins from alaskan seaweed inhibit carbolytic enzyme activity

Joshua Kellogg, Mary H. Grace, Mary Ann Lila, 2014, Marine Drugs on p. 5277-5294

Chemical and in vitro assessment of Alaskan coastal vegetation antioxidant capacity

Joshua Kellogg, Mary Ann Lila, 2013, Journal of agricultural and food chemistry on p. 11025-11032

Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes

Joshua Kellogg, Debora Esposito, Mary H. Grace, Slavko Komarnytsky, Mary Ann Lila, 2015, Journal of Functional Foods on p. 396-407

Biochemometrics to Identify Synergists and Additives from Botanical Medicines

Emily R. Britton, Joshua Kellogg, Olav M. Kvalheim, Nadja B. Cech, 2018, Journal of Natural Products on p. 484-493

Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations

Joshua J. Kellogg, Tyler N. Graf, Mary F. Paine, Jeannine S. McCune, Olav M. Kvalheim, Nicholas H. Oberlies, Nadja B. Cech, 2017, Journal of Natural Products on p. 1457-1466

Integration of Biochemometrics and Molecular Networking to Identify Antimicrobials in Angelica keiskei

Lindsay K. Caesar, Joshua J. Kellogg, Olav M. Kvalheim, Richard A. Cech, Nadja B. Cech, 2018, Planta Medica on p. 721-728

Conventional and accelerated-solvent extractions of green tea (camellia sinensis) for metabolomics-based chemometrics

Joshua J. Kellogg, Emily D. Wallace, Tyler N. Graf, Nicholas H. Oberlies, Nadja B. Cech, 2017, Journal of Pharmaceutical and Biomedical Analysis on p. 604-610

Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis)

Joseph M. Egan, Amninder Kaur, Huzefa A. Raja, Joshua J. Kellogg, Nicholas H. Oberlies, Nadja B. Cech, 2016, Phytochemistry Letters on p. 219-225