Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.
Huck Graduate Students
Publication TagsCulicidae Wolbachia Pathogens Genes Anopheles Viruses Arthropods Infections Infection Gene Editing Malaria Methodology Insecticides Virus Diseases Culex Anopheles Gambiae Mosquito Control Alpha Mannosidase Cryopreservation Microbiota Bacteria Genome Mosquito Vectors Animal Pathogens Insecta
Most Recent Publications
Sexual transmission of Anopheles gambiae densovirus (AgDNV) leads to disseminated infection in mated females
Kristine L. Werling, Rebecca M. Johnson, Hillery C. Metz, Jason L. Rasgon, 2022, Parasites and Vectors
Characterization of Mayaro virus (strain BeAn343102) biology in vertebrate and invertebrate cellular backgrounds
Sujit Pujhari, Marco Brustolin, Chan C. Heu, Ronald Smithwick, Mireia Larrosa, Susan Hafenstein, Jason L. Rasgon, 2022, Journal of General Virology
Assessing Aedes aegypti candidate genes during viral infection and Wolbachia-mediated pathogen blocking
Leah T. Sigle, Matthew Jones, Mario Novelo, Suzanne A. Ford, Nadya Urakova, Konstantinos Lymperopoulos, Richard T. Sayre, Zhiyong Xi, Jason L. Rasgon, Elizabeth A. McGraw, 2022, Insect Molecular Biology on p. 356-368
Cas9-mediated gene editing in the black-legged tick, Ixodes scapularis, by embryo injection and ReMOT Control
Arvind Sharma, Michael N. Pham, Jeremiah B. Reyes, Randeep Chana, Won C. Yim, Chan C. Heu, Donghun Kim, Duverney Chaverra-Rodriguez, Jason L. Rasgon, Robert A. Harrell, Andrew B. Nuss, Monika Gulia-Nuss, 2022, iScience
Cory Henderson, Marco Brustolin, Shivanand Hegde, Gargi Dayama, Nelson Lau, Grant L. Hughes, Christina Bergey, Jason L. Rasgon, 2022, PLoS Neglected Tropical Diseases
A microfluidic platform for highly parallel bite by bite profiling of mosquito-borne pathogen transmission
Shailabh Kumar, Felix J.H. Hol, Sujit Pujhari, Clayton Ellington, Haripriya Vaidehi Narayanan, Hongquan Li, Jason L. Rasgon, Manu Prakash, 2021, Nature Communications
Guan Hong Wang, Stephanie Gamez, Robyn R. Raban, John M. Marshall, Luke Alphey, Ming Li, Jason L. Rasgon, Omar S. Akbari, 2021, Nature Communications
Sujit Pujhari, Sanjeeta Paul, Jasmina Ahluwalia, Jason L. Rasgon, 2021, Reviews in Medical Virology
Emily N. Gallichotte, Karen M. Dobos, Gregory D. Ebel, Mary Hagedorn, Jason L. Rasgon, Jason H. Richardson, Timothy T. Stedman, Jennifer P. Barfield, 2021, Cryobiology on p. 1-10
Bradley J. Main, Matteo Marcantonio, J. Spencer Johnston, Jason L. Rasgon, C. Titus Brown, Christopher M. Barker, 2021, G3: Genes, Genomes, Genetics
Harnessing mosquito-Wolbachia symbiosis for vector and disease control
Kostas Bourtzis, Stephen L. Dobson, Zhiyong Xi, Jason L. Rasgon, Maurizio Calvitti, Luciano A. Moreira, Hervé C. Bossin, Riccardo Moretti, Luke Anthony Baton, Grant L. Hughes, Patrick Mavingui, Jeremie R.L. Gilles, 2014, Acta Tropica on p. S150-S163
Grant L. Hughes, Brittany L. Dodson, Rebecca M. Johnson, Courtney C. Murdock, Hitoshi Tsujimoto, Yasutsugu Suzuki, Alyssa A. Patt, Long Cui, Carlos W. Nossa, Rhiannon M. Barry, Joyce M. Sakamoto, Emily A. Hornett, Jason L. Rasgon, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 12498-12503
Brittany L. Dodson, Grant L. Hughes, Oluwatobi Paul, Amy C. Matacchiero, Laura D. Kramer, Jason L. Rasgon, 2014, PLoS Neglected Tropical Diseases
Shivanand Hegde, Jason L. Rasgon, Grant L. Hughes, 2015, Current Opinion in Virology on p. 97-102
Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing
Duverney Chaverra-Rodriguez, Vanessa M. Macias, Grant L. Hughes, Sujit Pujhari, Yasutsugu Suzuki, David R. Peterson, Donghun Kim, Sage McKeand, Jason L. Rasgon, 2018, Nature Communications
Transinfection: A method to investigate Wolbachia-host interactions and control arthropod-borne disease
G. L. Hughes, J. L. Rasgon, 2014, Insect Molecular Biology on p. 141-151
Courtney C. Murdock, Simon Blanford, Grant L. Hughes, Jason L. Rasgon, Matthew B. Thomas, 2014, Scientific Reports
Vanessa M. Macias, Johanna R. Ohm, Jason L. Rasgon, 2017, International Journal of Environmental Research and Public Health
Impact of trehalose transporter knockdown on Anopheles gambiae stress adaptation and susceptibility to Plasmodium falciparum infection
Kun Liu, Yuemei Dong, Yuzheng Huang, Jason L. Rasgon, Peter Agre, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 17504-17509
Sujit Pujhari, Marco Brustolin, Vanessa M. Macias, Ruth H. Nissly, Masashi Nomura, Suresh V. Kuchipudi, Jason L. Rasgon, 2019, Emerging Microbes and Infections on p. 8-16
News Articles Featuring Jason Rasgon
Nov 08, 2022
Faculty in College of Ag Sciences recognized for research achievements
Penn State’s College of Agricultural Sciences lauded outstanding accomplishments in research during the college’s inaugural Research Awards Ceremony, held Oct. 25 at the Hintz Family Alumni Center on the University Park campus.
Jul 12, 2022
Rasgon named Huck Chair of Disease Epidemiology and Biotechnology
Jason Rasgon, professor of entomology and disease epidemiology, has been named Dorothy Foehr Huck and J. Lloyd Huck Chair in Disease Epidemiology and Biotechnology.
May 25, 2022
Injecting Cockroaches with CRISPR Gene Edits Their Offspring
A new method has allowed researchers to conduct the first gene knock-out and knock-in edits on cockroaches and may extend to many other insects.
Mar 16, 2022
Huck Students Receive Alumni Awards
Two Huck IGDP students have been recognized as part of the 2021-22 Graduate School Alumni Association faculty and student awards in the Life & Health Sciences section.
Feb 16, 2022
Scientists develop gene-editing tools that may decrease tick-borne disease
In May 2021, scientists released the first batch of genetically-altered mosquitoes in the Florida Keys as part of a project to combat disease-carrying insects.The mosquitoes, modified versions of the Aedes aegypti species, is associated with several diseases, including Zika and yellow fever. Experts say using modified insects to control populations provides an alternative to insecticides, which some mosquitoes are evolving to develop immunity towards.
Feb 15, 2022
World’s first gene editing tools for ticks may help decrease tick-borne diseases
Reducing tick-borne diseases, such as Lyme disease, may now be possible thanks to two new gene editing methods developed by researchers at Penn State; the University of Nevada, Reno; and the University of Maryland. The methods could allow scientists to alter parts of the tick genome that are involved in harboring and transmitting pathogens.
Feb 17, 2021
Silencing the alarm
An enzyme in the saliva of certain insects prevents their food plants from warning neighboring plants of an attack.
Sep 09, 2020
More dengue fever and less malaria – mosquito control strategies may need to shift as Africa heats up
As it becomes too warm for comfort, the Anopheles mosquitoes that transmit malaria may lose the battle against climate change in Africa. But a new foe is on the horizon.
Aug 05, 2020
Gene-edited mosquitoes are ready for the U.S. — but is the U.S. ready for them?
In mid-June, Florida’s department of agriculture and consumer services approved a plan to release millions of genetically modified mosquitoes into the wild.
Apr 23, 2020
Gene-editing protocol for whitefly pest opens door to control
Whiteflies are among the most important agricultural pests in the world, yet they have been difficult to genetically manipulate and control, in part, because of their small size. An international team of researchers has overcome this roadblock by developing a CRISPR/Cas9 gene-editing protocol that could lead to novel control methods for this devastating pest.