David Boehr

Associate Professor of Chemistry

David Boehr

Research Summary

The role of protein dynamics in enzyme function, coordination and regulation

Huck Affiliations

Publication Tags

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Proteins Amino Acids Enzymes Rna Replicase Nucleotides Protein Acid Tryptophan Synthase Magnetic Resonance Spectroscopy Tryptophan Structural Dynamics Nucleotide Viral Rna Poliovirus Rna Nuclear Magnetic Resonance Computational Methods Biotechnology Nmr Spectroscopy Catalyst Triphosphoric Acid Catalysts Drug Substitution Reaction Antiviral Agents

Most Recent Publications

David D. Boehr, 2024, Frontiers in Molecular Biosciences

Rebecca N. D'Amico, David D. Boehr, 2023, Current Opinion in Structural Biology

David D. Boehr, Dennis S. Winston, Jie Yu, 2023, Biophysical Journal on p. 30a-31a

Jie Yu, David D. Boehr, 2023, Frontiers in Molecular Biosciences

Dennis S. Winston, David D. Boehr, 2022, Catalysts

Allosteric networks regulate function in multi-enzyme complexes

David D. Boehr, Rebecca D'Amico, Kathleen O'Rourke, Yuliana Bosken, Debashish Sahu, Chia En Chang, 2022, FASEB Journal

Differences in Conformational Dynamics Between a Viral Polyprotein and Its Processed Products in Functionally Relevant Regions Revealed by Solution-State NMR Spectroscopy

Dennis Winston, David Boehr, 2022, FASEB Journal

Most-Cited Papers

Lonneke van der Linden, Laia Vives-Adrián, Barbara Selisko, Cristina Ferrer-Orta, Xinran Liu, Kjerstin Lanke, Rachel Ulferts, Armando M. De Palma, Federica Tanchis, Nesya Goris, David Lefebvre, Kris De Clercq, Pieter Leyssen, Céline Lacroix, Gerhard Pürstinger, Bruno Coutard, Bruno Canard, David D. Boehr, Jamie J. Arnold, Craig E. Cameron, Nuria Verdaguer, Johan Neyts, Frank J.M. van Kuppeveld, 2015, PLoS Pathogens on p. 1-23

Kathleen F. O'Rourke, Scott D. Gorman, David D. Boehr, 2016, Computational and Structural Biotechnology Journal on p. 245-251

Amino acid networks in a (β/α)<sub>8</sub> barrel enzyme change during catalytic turnover

Jennifer M. Axe, Eric M. Yezdimer, Kathleen F. Orourke, Nicole E. Kerstetter, Wanli You, Chia En A. Chang, David D. Boehr, 2014, Journal of the American Chemical Society on p. 6818-6821

Ibrahim M. Moustafa, Victoria K. Korboukh, Jamie J. Arnold, Eric D. Smidansky, Laura L. Marcotte, David W. Gohara, Xiaorong Yang, María Antonieta Saánchez-Farraán, David Filman, Janna K. Maranas, David D. Boehr, James M. Hogle, Coray M. Colina, Craig E. Cameron, 2014, Journal of Biological Chemistry on p. 36229-36248

David D. Boehr, Rebecca N. D'Amico, Kathleen F. O'Rourke, 2018, Protein Science on p. 825-838

Jennifer M. Axe, Kathleen F. O'Rourke, Nicole E. Kerstetter, Eric M. Yezdimer, Yan M. Chan, Alexander Chasin, David D. Boehr, 2015, Protein Science on p. 484-494

Djoshkun Shengjuler, Yan Mei Chan, Simou Sun, Ibrahim M. Moustafa, Zhen Lu Li, David W. Gohara, Matthias Buck, Paul S. Cremer, David D. Boehr, Craig E. Cameron, 2017, Structure with Folding & design on p. 1875-1886.e7

Scott D. Gorman, Debashish Sahu, Kathleen F. O'Rourke, David D. Boehr, 2018, ImmunoMethods on p. 88-99

Xiaorong Yang, Xinran Liu, Derek M. Musser, Ibrahim M. Moustafa, Jamie J. Arnold, Craig E. Cameron, David D. Boehr, 2017, Journal of Biological Chemistry on p. 3810-3826

Jingjing Shi, Jacob M. Perryman, Xiaorong Yang, Xinran Liu, Derek M. Musser, Alyson K. Boehr, Ibrahim M. Moustafa, Jamie J. Arnold, Craig E. Cameron, David D. Boehr, 2019, Biochemistry on p. 3735-3743