Jason Rasgon

Professor of Entomology and Disease Epidemiology

Jason Rasgon

Research Summary

Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.

Huck Graduate Students

Huck Affiliations

Publication Tags

Culicidae Wolbachia Malaria Infection Anopheles Anopheles Gambiae Parasites Insects Insecta Viruses Methodology Pathogens Virus Diseases Culex Mutagenesis Plasmodium Berghei Cryopreservation Microbiota Ribonucleoproteins Peptides Enzymes Insecticides Arthropods Phenotype Animal Pathogens

Most Recent Papers

Core commitments for field trials of gene drive organisms

Kanya C. Long, Luke Alphey, George J. Annas, Cinnamon S. Bloss, Karl J. Campbell, Jackson Champer, Chun Hong Chen, Amit Choudhary, George M. Church, James P. Collins, Kimberly L. Cooper, Jason A. Delborne, Owain R. Edwards, Claudia I. Emerson, Kevin Esvelt, Sam Weiss Evans, Robert M. Friedman, Valentino M. Gantz, Fred Gould, Sarah Hartley, Elizabeth Heitman, Janet Hemingway, Hirotaka Kanuka, Jennifer Kuzma, James V. Lavery, Yoosook Lee, Marce Lorenzen, Jeantine E. Lunshof, John M. Marshall, Philipp W. Messer, Craig Montell, Kenneth A. Oye, Megan J. Palmer, Philippos Aris Papathanos, Prasad N. Paradkar, Antoinette J. Piaggio, Jason L. Rasgon, Gordana Rašic, Larisa Rudenko, J. Royden Saah, Maxwell J. Scott, Jolene T. Sutton, Adam E. Vorsino, Omar S. Akbari, 2021, Science on p. 1417-1419

Clotting disorder in severe acute respiratory syndrome coronavirus 2

Sujit Pujhari, Sanjeeta Paul, Jasmina Ahluwalia, Jason L. Rasgon, 2021, Reviews in Medical Virology

Towards a method for cryopreservation of mosquito vectors of human pathogens

Emily N. Gallichotte, Karen M. Dobos, Gregory D. Ebel, Mary Hagedorn, Jason L. Rasgon, Jason H. Richardson, Timothy T. Stedman, Jennifer P. Barfield, 2021, Cryobiology on p. 1-10

Whole-genome assembly of Culex tarsalis

Bradley J. Main, Matteo Marcantonio, J. Spencer Johnston, Jason L. Rasgon, C. Titus Brown, Christopher M. Barker, 2021, G3: Genes, Genomes, Genetics

Leaning Into the Bite

Vanessa M. Macias, Umberto Palatini, Mariangela Bonizzoni, Jason L. Rasgon, 2021, Frontiers in cellular and infection microbiology

Silencing the alarm: an insect salivary enzyme closes plant stomata and inhibits volatile release

Po-An Lin, Yintong Chen, Duverney Chaverra-Rodriguez, Chan Heu, Bin Zainuddin, Nursyafiqi, Jagdeep Sidhu, Jagdeep Sidhu, Michelle Peiffer, Michelle Peiffer, Ching-Wen Tan, Ching-Wen Tan, Anjel Helms, Anjel Helms, Donghun Kim, Donghun Kim, Jared Ali, Jared Ali, J Rasgon, J Rasgon, J Lynch, J Lynch, C Anderson, C Anderson, G Felton, G Felton, 2021, New Phytologist

A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons

Qicheng Ma, Satyam P. Srivastav, Stephanie Gamez, Gargi Dayama, Fabiana Feitosa-Suntheimer, Edward I. Patterson, Rebecca M. Johnson, Erik M. Matson, Alexander S. Gold, Douglas E. Brackney, John H. Connor, Tonya M. Colpitts, Grant L. Hughes, Jason L. Rasgon, Tony Nolan, Omar S. Akbari, Nelson C. Lau, 2021, Genome Research on p. 512-528

Germline mutagenesis of Nasonia vitripennis through ovarian delivery of CRISPR-Cas9 ribonucleoprotein

D. Chaverra-Rodriguez, E. Dalla Benetta, C. C. Heu, J. L. Rasgon, P. M. Ferree, O. S. Akbari, 2020, Insect Molecular Biology on p. 569-577

Actin bundles play a different role in shaping scales compared to bristles in the mosquito Aedes aegypti

Sanja Djokic, Anna Bakhrat, Ido Tsurim, Nadya Urakova, Jason L. Rasgon, Uri Abdu, 2020, Scientific Reports

Anopheles gambiae densovirus (AgDNV) negatively affects Mayaro virus infection in Anopheles gambiae cells and mosquitoes

Nadya Urakova, Marco Brustolin, Renuka E. Joseph, Rebecca M. Johnson, Sujit Pujhari, Jason L. Rasgon, 2020, Parasites and Vectors

Most-Cited Papers

Wolbachia infections are virulent and inhibit the human malaria parasite Plasmodium falciparum in Anopheles gambiae

Grant L. Hughes, Ryuichi Koga, Ping Xue, Takema Fukatsu, Jason L. Rasgon, 2011, PLoS Pathogens

Harnessing mosquito-Wolbachia symbiosis for vector and disease control

Kostas Bourtzis, Stephen L. Dobson, Zhiyong Xi, Jason L. Rasgon, Maurizio Calvitti, Luciano A. Moreira, Hervé C. Bossin, Riccardo Moretti, Luke Anthony Baton, Grant L. Hughes, Patrick Mavingui, Jeremie R.L. Gilles, 2014, Acta Tropica on p. S150-S163

Native microbiome impedes vertical transmission of Wolbachia in Anopheles mosquitoes

Grant L. Hughes, Brittany L. Dodson, Rebecca M. Johnson, Courtney C. Murdock, Hitoshi Tsujimoto, Yasutsugu Suzuki, Alyssa A. Patt, Long Cui, Carlos W. Nossa, Rhiannon M. Barry, Joyce Megumi Sakamoto, Emily A. Hornett, Jason Laurence Rasgon, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 12498-12503

Wolbachia Enhances West Nile Virus (WNV) Infection in the Mosquito Culex tarsalis

Brittany L. Dodson, Grant L. Hughes, Oluwatobi Paul, Amy C. Matacchiero, Laura D. Kramer, Jason L. Rasgon, 2014, PLoS Neglected Tropical Diseases

The microbiome modulates arbovirus transmission in mosquitoes

Shivanand Hegde, Jason L. Rasgon, Grant L. Hughes, 2015, Current Opinion in Virology on p. 97-102

Wolbachia infections in Anopheles gambiae cells

Grant L. Hughes, Xiaoxia Ren, Jose L. Ramirez, Joyce M. Sakamoto, Jason A. Bailey, Anne E. Jedlicka, Jason L. Rasgon, 2011, PLoS Pathogens on p. e1001296

Endectocides for malaria control

Brian D. Foy, Kevin C. Kobylinski, Ines Marques da Silva, Jason L. Rasgon, Massamba Sylla, 2011, Trends in Parasitology on p. 423-428

Wolbachia strain wAlbB enhances infection by the rodent malaria parasite Plasmodium berghei in Anopheles gambiae mosquitoes

Grant L. Hughes, Joel Vega-Rodriguez, Ping Xue, Jason L. Rasgon, 2012, Applied and Environmental Microbiology on p. 1491-1495

Transinfection

G. L. Hughes, J. L. Rasgon, 2014, Insect Molecular Biology on p. 141-151

Temperature alters Plasmodium blocking by Wolbachia

Courtney C. Murdock, Simon Blanford, Grant L. Hughes, Jason L. Rasgon, Matthew B. Thomas, 2014, Scientific Reports

News Articles Featuring Jason Rasgon

Silencing the alarm

An enzyme in the saliva of certain insects prevents their food plants from warning neighboring plants of an attack.

More dengue fever and less malaria – mosquito control strategies may need to shift as Africa heats up

As it becomes too warm for comfort, the Anopheles mosquitoes that transmit malaria may lose the battle against climate change in Africa. But a new foe is on the horizon.

Gene-edited mosquitoes are ready for the U.S. — but is the U.S. ready for them?

In mid-June, Florida’s department of agriculture and consumer services approved a plan to release millions of genetically modified mosquitoes into the wild.

Gene-editing protocol for whitefly pest opens door to control

Whiteflies are among the most important agricultural pests in the world, yet they have been difficult to genetically manipulate and control, in part, because of their small size. An international team of researchers has overcome this roadblock by developing a CRISPR/Cas9 gene-editing protocol that could lead to novel control methods for this devastating pest.

Study on DNA spread by genetically modified mosquitoes prompts backlash

For 10 years, the company Oxitec has been testing whether genetically modified (GM) mosquitoes can suppress populations of their natural brethren, which carry devastating viruses such as Zika and dengue. Its strategy: Deploy (nonbiting) male Aedes aegypti mosquitoes bearing a gene that should doom most of their offspring before adulthood.

Graphene film promising for blocking mosquitoes

Health officials are touting a new protection against bloodsucking insects amid reports of a rare mosquito-borne disease that has infected four people in Massachusetts, killing one woman.

Scientists Are Tweeting About The Strangest Experiments They've Ever Done

Anopheles Mosquitoes Could Spread Mayaro Virus in U.S.

Mosquitoes of the genus Anopheles are well known as primary vectors of malaria. But a new study suggests that Anopheles species, including some found in the United States, also are capable of carrying and transmitting an emerging pathogen, Mayaro virus, which has caused outbreaks of disease in South America and the Caribbean.