Donna Korzick
Director of Graduate Training Initiatives; Professor of Physiology and Kinesiology
-
106 Noll Lab
University Park, PA 16802 - dhk102@psu.edu
- 814-865-5679
Research Summary
My research is focused on aging, post-menopausal women, and cardiac ischemia reperfusion injury using animal models. We are particularly interested in the effects of estrogen deficiency on mitochondrial regulation of cell survival following myocardial infarction. Multiple levels of inquiry addressing mitochondrial quality control regulation and immune signaling is emphasized.
Huck Graduate Students
Huck Affiliations
Links
Most Recent Publications
Phenotypic Characterization of Macrophage and Monocyte Populations in the NLRP3 KO DAHL/SS-Nlrp3<sup>em2Mcwi</sup> Rat Model
Cesar De Jeronimo Diaz, Jiajing Teng, Ryan A. Flynn, Matthew Lin, Junyao Yuan, Connie J. Rogers, Donna H. Korzick, 2022, FASEB Journal
Evans Blue Dye Interferes with Gating for Certain Fluorochrome-Conjugated Antibodies Using Flow Cytometry in the Ischemic Rat Heart
Jiajing Teng, Cesar De Jeronimo Diaz, Ryan A. Flynn, Matthew Lin, Connie J. Rogers, Donna H. Korzick, 2022, FASEB Journal
Inhibition of programmed necrosis limits infarct size through altered mitochondrial and immune responses in the aged female rat heart
Alexandra M. Garvin, Morgan A. Jackson, Donna H. Korzick, 2018, American Journal of Physiology on p. H1434-H1442
Age and ischemia differentially impact mitochondrial ultrastructure and function in a novel model of age-associated estrogen deficiency in the female rat heart
Alexandra M. Garvin, Nicole C. Aurigemma, Jenna L. Hackenberger, Donna H. Korzick, 2017, Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere on p. 1591-1602
Evidence of Altered Mitochondrial Protein Expression After Chronic Ethanol Consumption in the Aged Estrogen-Deficient Female Rat Heart
Alexandra M. Garvin, Jennifer L. Miller-Lee, Daniel R. Sharda, Gregory M. Kanski, J. Craig Hunter, Donna H. Korzick, 2017, Alcoholism: Clinical and Experimental Research on p. 1288-1297
Acute adiponectin delivery is cardioprotective in the aged female rat heart
Nanette J. Tomicek, Craig J. Hunter, Alexandra M. Machikas, Veronica Lopez, Donna H. Korzick, 2015, Geriatrics and Gerontology International on p. 636-646
Estrogen and the female heart
A. A. Knowlton, D. H. Korzick, 2014, Molecular and Cellular Endocrinology on p. 31-39
Chronic alcohol consumption disrupts myocardial protein balance and function in aged, but not adult, female F344 rats
Charles H. Lang, Donna H. Korzick, 2014, American Journal of Physiology on p. R23-R33
Divergent effects of aging and sex on vasoconstriction to endothelin in coronary arterioles
Amanda J. Leblanc, Bei Chen, Patrick J. Dougherty, Rafael A. Reyes, Robert D. Shipley, Donna H. Korzick, Judy M. Muller-Delp, 2013, Microcirculation on p. 365-376
Aging accentuates alcohol-induced decrease in protein synthesis in gastrocnemius
Donna H. Korzick, Daniel R. Sharda, Anne M. Pruznak, Charles H. Lang, 2013, American Journal of Physiology on p. R887-R898
Most-Cited Papers
Inhibition of programmed necrosis limits infarct size through altered mitochondrial and immune responses in the aged female rat heart
Alexandra M. Garvin, Morgan A. Jackson, Donna H. Korzick, 2018, American Journal of Physiology on p. H1434-H1442
Age and ischemia differentially impact mitochondrial ultrastructure and function in a novel model of age-associated estrogen deficiency in the female rat heart
Alexandra M. Garvin, Nicole C. Aurigemma, Jenna L. Hackenberger, Donna H. Korzick, 2017, Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere on p. 1591-1602
Acute adiponectin delivery is cardioprotective in the aged female rat heart
Nanette J. Tomicek, Craig J. Hunter, Alexandra M. Machikas, Veronica Lopez, Donna H. Korzick, 2015, Geriatrics and Gerontology International on p. 636-646
Evidence of Altered Mitochondrial Protein Expression After Chronic Ethanol Consumption in the Aged Estrogen-Deficient Female Rat Heart
Alexandra M. Garvin, Jennifer L. Miller-Lee, Daniel R. Sharda, Gregory M. Kanski, J. Craig Hunter, Donna H. Korzick, 2017, Alcoholism: Clinical and Experimental Research on p. 1288-1297
Phenotypic Characterization of Macrophage and Monocyte Populations in the NLRP3 KO DAHL/SS-Nlrp3<sup>em2Mcwi</sup> Rat Model
Cesar De Jeronimo Diaz, Jiajing Teng, Ryan A. Flynn, Matthew Lin, Junyao Yuan, Connie J. Rogers, Donna H. Korzick, 2022, FASEB Journal
Evans Blue Dye Interferes with Gating for Certain Fluorochrome-Conjugated Antibodies Using Flow Cytometry in the Ischemic Rat Heart
Jiajing Teng, Cesar De Jeronimo Diaz, Ryan A. Flynn, Matthew Lin, Connie J. Rogers, Donna H. Korzick, 2022, FASEB Journal
News Articles Featuring Donna Korzick
Apr 25, 2025
Penn State graduate students receive American Heart Association fellowships
Two Penn State graduate students enrolled in Intercollege Graduate Degree Programs administered by the Huck Institutes of the Life Sciences have each been awarded two-year American Heart Association (AHA) Postdoctoral Fellowships.
Full Article
Dec 19, 2024
New Annual Summit Focuses on Graduate Student Resiliency
Earlier this month, the Huck Institutes, in partnership with the J. Jeffrey and Ann Marie Fox Graduate School at Penn State, hosted the Inaugural Huck Institutes T32 Summit.
Full Article
Dec 16, 2024
Two Huck graduate students receive American Heart Association fellowships
Two Huck graduate students awarded individual 2-year American Heart Association fellowships.
Full Article
Jun 21, 2024
Physiological Adaptations to Stress graduate training program awarded $2.75M
Penn State’s Physiological Adaptations to Stress graduate training program received renewed funding of $2.75 million from the National Institutes of Health's National Institute of General Medical Sciences.
Full Article
Sep 21, 2023
Huck-supported graduate degree programs transition to new leadership
David Koslicki and Greg Shearer have stepped into the leadership roles for the Huck's Bioinformatics and Genomics (BG) and Physiology graduate programs.
Full Article
Apr 24, 2023
Donna Korzick leads training grant initiatives to new highs
There are many things Penn State does to improve the research environment for graduate students, from investments in instrumentation to the availability of mental health resources to recruitment of quality seminar speakers.
Full Article
Jul 27, 2021
Business Bootcamp marks restart of in-person graduate training
After 17 months of pandemic-necessitated online instruction, something resembling normalcy returned to the Huck as grad students were exposed to new career opportunities by the July 18-22 Business of Science bootcamp.
Full Article
Jun 16, 2021
Improving heart health for older women
Heart attacks are the leading cause of death among postmenopausal women. New funding from the National Institute on Aging will enable Penn State researchers to explore the links between tiny receptors in our immune systems called inflammasomes and how/when cells die. These links may enable researchers to develop new therapies to treat and prevent heart disease in older women.
Full Article
Apr 08, 2021
New position will support graduate and post-graduate training
Donna Korzick, professor of physiology and kinesiology, recently assumed a new role as director of graduate training initiatives in the Huck Institutes for the Life Sciences. In this role, Korzick is dedicating half of her time to support the application for and execution of training grants from organizations like the National Institutes of Health.
Full Article
Mar 08, 2021
New Appointments to Build on Excellence in Graduate Training
Two familiar faces within the Huck's graduate program system will be adding new roles to support the Institutes' portfolio of extramurally-funded programs.
Full Article