News

Jun 03, 2021

New images of canine parvovirus may help predict how virus jumps to new species

​Canine parvovirus (CPV) is a highly infectious pathogen that causes severe diseases in unvaccinated dogs, including inflammation of the heart and acute gastrointestinal illness. Originating in cats, the virus is a rare example of a DNA-based virus that can jump between species, and a team of researchers’ discovery may help in predicting this and the virus’ ability to evolve, which could have implications for current vaccines used in dogs.

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May 10, 2021

Pioneering chemist Stephen Benkovic elected Foreign Member of Royal Society 6

Stephen Benkovic, Evan Pugh Professor and Holder of the Eberly Family Chair in Chemistry at Penn State, has been elected a Foreign Member of the Royal Society, the national academy of science in the United Kingdom. The society, founded in 1660, aims to recognize, promote and support excellence in science and to encourage the development and use of science for the benefit of humanity.

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Jan 25, 2021

Regulating the ribosomal RNA production line

Cryo-electron microscopy study allows researchers to visualize structural changes in an E. coli enzyme synthesizing ribosomal RNA that shift it between turbo- and slow-modes depending on the bacteria’s growth rate

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Nov 23, 2020

Altered 'coat' disguises fatal brain virus from neutralizing antibodies

A genetic modification in the ‘coat’ of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers.

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Aug 12, 2020

Determining how a coronavirus protein takes over human protein-making machinery

Jean-Paul Armache, assistant professor of biochemistry and molecular biology, has been awarded seed funding from the Huck Institutes of the Life Sciences at Penn State to use cryo-electron microscopy to study how an important SARS-CoV-2 protein binds to and takes over the human ribosome — a protein factory in the cell that the virus uses to copy itself.

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Jun 05, 2020

New image of a cancer-related enzyme in action helps explain gene regulation

New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells — including cancer cells — regulate their genes.

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Sep 24, 2019

Virus may jump species through 'rock-and-roll' motion with receptors

Like a janitor thumbing through a keychain to find just the right key to open a lock, the "rock-and-roll" motion of the canine parvovirus during the binding process may help explain how the virus can find the spot on a receptor to infect not just dogs, but multiple species, according to an international team of researchers.

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