Weihua Guan
Assistant Professor of Electrical Engineering
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111F Electrical Engineering West
University Park, PA - wzg111@psu.edu
- 814-867-5748
Publication Tags
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Nucleic Acids Nanopores Sensors Glass Ions Parasites Nucleic Acid Clustered Regularly Interspaced Short Palindromic Repeats Equipment And Supplies Molecules Testing Time Dna Amplification Costs And Cost Analysis Blood Malaria Fluorescence Microfluidics Costs Fluids Solid State Figure Of Merit Fabrication IonMost Recent Publications
STAMP-Based Digital CRISPR-Cas13a for Amplification-Free Quantification of HIV-1 Plasma Viral Loads
Reza Nouri, Yuqian Jiang, Anthony J. Politza, Tianyi Liu, Wallace H. Greene, Yusheng Zhu, Jonathan J. Nunez, Xiaojun Lian, Weihua Guan, 2023, ACS Nano on p. 10701-10712
Fully integrated point-of-care blood cell count using multi-frame morphology analysis
Wenchang Zhang, Ya Li, Bing Chen, Yuan Zhang, Ziqiang Du, Feibin Xiang, Yu Hu, Xiaochen Meng, Chunliang Shang, Shengfa Liang, Xiaonan Yang, Weihua Guan, 2023, Biosensors and Bioelectronics
Handheld Purification-Free Nucleic Acid Testing Device for Point-of-Need Detection of Malaria from Whole Blood
Aneesh Kshirsagar, Gihoon Choi, Vishaka Santosh, Tara Harvey, Robert Cory Bernhards, Weihua Guan, 2023, ACS Sensors on p. 673-683
Digital CRISPR systems for the next generation of nucleic acid quantification
Anthony J. Politza, Reza Nouri, Weihua Guan, 2023, TrAC - Trends in Analytical Chemistry
Morphology around Nanopores Fabricated by Laser-Assisted Dielectric Breakdown and Its Impact on Ion and DNA Transport and Sensing
Ming Dong, Reza Nouri, Zifan Tang, Weihua Guan, 2023, ACS applied materials & interfaces
Modeling pyramidal silicon nanopores with effective ion transport
Feibin Xiang, Ming Dong, Wenchang Zhang, Shengfa Liang, Weihua Guan, 2022, Nanotechnology
Figure of Merit for CRISPR-Based Nucleic Acid-Sensing Systems: Improvement Strategies and Performance Comparison
Reza Nouri, Ming Dong, Anthony J. Politza, Weihua Guan, 2022, ACS Sensors on p. 900-911
Rapid detection of novel coronavirus SARS-CoV-2 by RT-LAMP coupled solid-state nanopores
Zifan Tang, Reza Nouri, Ming Dong, Jianbo Yang, Wallace Greene, Yusheng Zhu, Michele Yon, Meera Surendran Nair, Suresh V. Kuchipudi, Weihua Guan, 2022, Biosensors and Bioelectronics
An Ultracompact Real-Time Fluorescence Loop-Mediated Isothermal Amplification (LAMP) Analyzer
Gihoon Choi, Weihua Guan, 2022, on p. 257-278
Sample-to-Answer Microfluidic Nucleic Acid Testing (NAT) on Lab-on-a-Disc for Malaria Detection at Point of Need
Gihoon Choi, Weihua Guan, 2022, on p. 297-313
Most-Cited Papers
CRISPR-based detection of SARS-CoV-2: A review from sample to result
Reza Nouri, Zifan Tang, Ming Dong, Tianyi Liu, Aneesh Kshirsagar, Weihua Guan, 2021, Biosensors and Bioelectronics
Sequence-Specific Recognition of HIV-1 DNA with Solid-State CRISPR-Cas12a-Assisted Nanopores (SCAN)
Reza Nouri, Yuqian Jiang, Xiaojun Lance Lian, Weihua Guan, 2020, ACS Sensors on p. 1273-1280
Voltage gated ion and molecule transport in engineered nanochannels: Theory, fabrication and applications
Weihua Guan, Sylvia Xin Li, Mark A. Reed, 2014, Nanotechnology
Direct Observation of Charge Inversion in Divalent Nanofluidic Devices
Sylvia Xin Li, Weihua Guan, Benjamin Weiner, Mark A. Reed, 2015, Nano Letters on p. 5046-5051
Highly specific and sensitive non-enzymatic determination of uric acid in serum and urine by extended gate field effect transistor sensors
Weihua Guan, Xuexin Duan, Mark A. Reed, 2014, Biosensors and Bioelectronics on p. 225-231
Sample-to-answer palm-sized nucleic acid testing device towards low-cost malaria mass screening
Gihoon Choi, Theodore Prince, Jun Miao, Liwang Cui, Weihua Guan, 2018, Biosensors and Bioelectronics on p. 83-90
Noise in nanopore sensors: Sources, models, reduction, and benchmarking
Shengfa Liang, Feibin Xiang, Zifan Tang, Reza Nouri, Xiaodong He, Ming Dong, Weihua Guan, 2020, Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering on p. 9-17
A field-deployable mobile molecular diagnostic system for malaria at the point of need
Gihoon Choi, Daniel Song, Sony Shrestha, Jun Miao, Liwang Cui, Weihua Guan, 2016, Lab on a Chip - Miniaturisation for Chemistry and Biology on p. 4341-4349
Detection of SARS-CoV-2 with Solid-State CRISPR-Cas12a-Assisted Nanopores
Reza Nouri, Yuqian Jiang, Zifan Tang, Xiaojun Lance Lian, Weihua Guan, 2021, Nano Letters on p. 8393-8400
Loop-Mediated Isothermal Amplification-Coupled Glass Nanopore Counting Toward Sensitive and Specific Nucleic Acid Testing
Zifan Tang, Gihoon Choi, Reza Nouri, Weihua Guan, 2019, Nano Letters on p. 7927-7934
News Articles Featuring Weihua Guan
Jun 20, 2023
Penn State researchers develop digital test to directly measure HIV viral load
A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies.
Full Article
Aug 05, 2022
New at-home, saliva-based COVID test as effective as PCR in preliminary analysis
PCR tests, also called molecular tests or nucleic acid tests, are considered the gold standard in detecting the presence of SARS-CoV-2, the virus that gives rise to COVID-19. However, they can take a few days to process, resulting in unnecessary quarantine for negative individuals or delays for those who require proof of negative testing for travel or other commitments.
Full Article
Apr 01, 2020
Penn State engineer developing device that may be able to test for COVID-19
A point-of-care testing device that may help diagnose the novel coronavirus disease (COVID-19) is under development by Weihua Guan, assistant professor of electrical engineering in Penn State’s College of Engineering.
Full Article
Mar 23, 2020
Penn State funds first round of COVID-19 research proposals
One week after launching a rapid-fire call for proposals, awards are granted to six projects that address the global pandemic, with more to follow
Full Article