Tim Miyashiro

Assistant Professor of Biochemistry and Molecular Biology

410 Frear South
University Park, PA
tim14@psu.edu
814-865-1916

Research Summary

How bacteria adapt to a host environment. The mutualistic symbiosis established between the Hawaiian bobtail squid (Euprymna scolopes) and a bioluminescent bacterium (Vibrio fischeri).

Huck Graduate Students

Jessica Eason

Huck Affiliations

Molecular, Cellular, and Integrative Biosciences

Microbiome Center

Center for Infectious Disease Dynamics

Center for Chemical Ecology

Publication Tags

Aliivibrio Fischeri Symbiosis Decapodiformes Light Bacteria Luminescence Type Vi Secretion Systems Vibrio Vibrio Fischeri Symbionts Symbiont Genes Intraspecific Competition Organ Population Squid Bioluminescence Persistence Animals Colonization Genome In Vitro Techniques Strain Differences Niches Niche

Most Recent Publications

Quorum Sensing Facilitates Interpopulation Signaling by Vibrio fischeri within the Light Organ of Euprymna scolopes

Taylor A. Yount, Andrew N. Murtha, Andrew G. Cecere, Tim I. Miyashiro, 2022, Israel Journal of Chemistry

Vibrio fischeri imports and assimilates sulfate during symbiosis with Euprymna scolopes

Nathan P. Wasilko, Josue S. Ceron, Emily R. Baker, Andrew G. Cecere, Michael S. Wollenberg, Tim I. Miyashiro, 2021, Molecular Microbiology on p. 926-942

The bacterial enhancer binding protein vasH promotes expression of a type vi secretion system in vibrio fischeri during symbiosis

Kirsten R. Guckes, Andrew G. Cecere, Amanda L. Williams, Anjali E. McNeil, Tim Miyashiro, 2020, Journal of Bacteriology

Incompatibility of vibrio fischeri strains during symbiosis establishment depends on two functionally redundant hcp genes

Kirsten R. Guckes, Andrew G. Cecere, Nathan P. Wasilko, Amanda L. Williams, Katherine M. Bultman, Mark J. Mandel, Tim Miyashiro, 2019, Journal of Bacteriology

Draft genome sequences of type VI secretion system-encoding vibrio fischeri strains FQ-A001 and ES401

Katherine M. Bultman, Andrew G. Cecere, Tim Miyashiro, Alecia N. Septer, Mark J. Mandel, 2019, Microbiology Resource Announcements

Sulfur availability for Vibrio fischeri growth during symbiosis establishment depends on biogeography within the squid light organ

Nathan P. Wasilko, Jessie Larios-Valencia, Caroline H. Steingard, Briana M. Nunez, Subhash C. Verma, Tim Miyashiro, 2019, Molecular Microbiology on p. 621-636

Sulfur availability for Vibrio fischeri growth during symbiosis establishment depends on biogeography within the squid light organ

Nathan Wasilko, Jessie Larios-Valencia, Caroline Steingard, Briana Nunez, Subhash Verma, Tim Miyashiro, 2018, Molecular Microbiology

Bacterial symbionts use a type VI secretion system to eliminate competitors in their natural host

Lauren Speare, Andrew G. Cecere, Kirsten R. Guckes, Stephanie Smith, Michael S. Wollenberg, Mark J. Mandel, Tim Miyashiro, Alecia N. Septer, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. E8528-E8537

Intraspecific competition impacts Vibrio fischeri strain diversity during initial colonization of the squid light organ

Yan Sun, Elijah D. LaSota, Andrew G. Cecere, Kyle B. LaPenna, Jessie Larios-Valencia, Michael S. Wollenberg, Tim Miyashiro, 2016, Applied and Environmental Microbiology on p. 3082-3091

Niche-specific impact of a symbiotic function on the persistence of microbial symbionts within a natural host

Subhash C. Verma, Tim Miyashiro, 2016, Applied and Environmental Microbiology on p. 5990-5996

Most-Cited Papers

Bacterial symbionts use a type VI secretion system to eliminate competitors in their natural host

Quorum sensing in the squid-Vibrio symbiosis.

Subhash C. Verma, Tim Miyashiro, 2013, International Journal of Molecular Sciences on p. 16386-16401

Features governing symbiont persistence in the squid-vibrio association

Eric J. Koch, Tim Miyashiro, Margaret J. McFall-Ngai, Edward G. Ruby, 2014, Molecular Ecology on p. 1624-1634

Competence and natural transformation in vibrios

Yan Sun, Eryn E. Bernardy, Brian K. Hammer, Tim Miyashiro, 2013, Molecular Microbiology on p. 583-595

Intraspecific competition impacts Vibrio fischeri strain diversity during initial colonization of the squid light organ

Yan Sun, Elijah D. LaSota, Andrew G. Cecere, Kyle B. LaPenna, Jessie Larios-Valencia, Michael S. Wollenberg, Tim Miyashiro, 2016, Applied and Environmental Microbiology on p. 3082-3091

The putative oligosaccharide translocase SypK connects biofilm formation with quorum signaling in Vibrio fischeri

Tim Miyashiro, Dane Oehlert, Valerie A. Ray, Karen L. Visick, Edward G. Ruby, 2014, MicrobiologyOpen on p. 836-848

Incompatibility of vibrio fischeri strains during symbiosis establishment depends on two functionally redundant hcp genes

Kirsten R. Guckes, Andrew G. Cecere, Nathan P. Wasilko, Amanda L. Williams, Katherine M. Bultman, Mark J. Mandel, Tim Miyashiro, 2019, Journal of Bacteriology

NagC represses N-acetyl-glucosamine utilization genes in Vibrio fischeri within the light organ of Euprymna scolopes

Yan Sun, Subhash C. Verma, Haikel Bogale, Tim Miyashiro, 2015, Frontiers in Microbiology