Thomas Gould

Jean Phillips Shibley Professor and Department Head of Biobehavioral Health

Thomas Gould

Research Summary

Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.

Huck Graduate Students

Huck Affiliations


Publication Tags

Nicotine Fear Hippocampus Learning Memory Anxiety Therapeutics Conditioning (Psychology) Tobacco Use Disorder Inhibition (Psychology) Conditioning Psychological Inhibition Genetic Background Pharmaceutical Preparations Inbred Strains Mice Maintenance Rodentia Inbred C57bl Mouse Cocaine Length Genes Neurotransmitter Agents Street Drugs Ethanol Data Storage Equipment

Most Recent Papers

Genetic Influences Impacting Nicotine Use and Abuse During Adolescence: Insights from Human and Rodent Studies

L Goldberg, Thomas Gould, Brain Research Bulletin

The impact of adolescent stress on nicotine use and affective disorders in rodent models

Sean M. Mooney-Leber, Michael J. Caruso, Thomas J. Gould, Sonia A. Cavigelli, Helen M. Kamens, 2022, European Journal of Neuroscience on p. 2196-2215

Balancing Risks and Benefits of E-Cigarettes in the Real World.

J Cohen, S Krishnan-Sarin, T Eissenberg, Thomas Gould, M Berman, A Bhatnagar, T Barnett, E Soule, L Popova, Tan ASL, M Blank, P Ling, R O'Connor, 2022, American journal of public health on p. e1-e2

Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains

Sean M. Mooney-Leber, Dana Zeid, Prescilla Garcia-Trevizo, Laurel R. Seemiller, Molly A. Bogue, Stephen C. Grubb, Gary Peltz, Thomas J. Gould, 2021, Frontiers in Psychiatry

Genetic background determines behavioral responses during fear conditioning

L. R. Seemiller, S. M. Mooney-Leber, E. Henry, A. McGarvey, A. Druffner, G. Peltz, T. J. Gould, 2021, Communications in behavioral biology. Part A: [Original articles]

Terc gene cluster variants predict liver telomere length in mice

Dana Zeid, Sean Mooney-Leber, Laurel R. Seemiller, Lisa R. Goldberg, Thomas J. Gould, 2021, Cells

Genes and behavior: Animal models

Thomas J. Gould, Lisa R. Goldberg, 2021, on p. 255-262

Adult and adolescent C57BL/6J and DBA/2J mice are differentially susceptible to fear learning deficits after acute ethanol or MK-801 treatment

L. R. Seemiller, T. J. Gould, 2021, Behavioural Brain Research

Therapeutic potential of ketamine for alcohol use disorder

Stephen D. Worrell, Thomas J. Gould, 2021, Neuroscience and Biobehavioral Reviews on p. 573-589

Adolescent Stress Reduces Adult Morphine-Induced Behavioral Sensitization in C57BL/6J Mice

Helen M. Kamens, Carley N. Miller, Jasmine I. Caulfield, Dana Zeid, William J. Horton, Constanza P. Silva, Aswathy Sebastian, Istvan Albert, Thomas J. Gould, Diana Fishbein, Patricia Sue Grigson, Sonia A. Cavigelli, 2021, Frontiers in Behavioral Neuroscience

Most-Cited Papers

The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition

Sheree F. Logue, Thomas J. Gould, 2014, Pharmacology Biochemistry and Behavior on p. 45-54

Effects of drugs of abuse on hippocampal plasticity and hippocampus-dependent learning and memory

Munir Gunes Kutlu, Thomas J. Gould, 2016, Learning and Memory on p. 515-533

Developmental toxicity of nicotine

Lucinda J. England, Kjersti Aagaard, Michele Bloch, Kevin Conway, Kelly Cosgrove, Rachel Grana, Thomas J. Gould, Dorothy Hatsukami, Frances Jensen, Denise Kandel, Bruce Lanphear, Frances Leslie, James R. Pauly, Jenae Neiderhiser, Mark Rubinstein, Theodore A. Slotkin, Eliot Spindel, Laura Stroud, Lauren Wakschlag, 2017, Neuroscience and Biobehavioral Reviews on p. 176-189

Elective Cancer Surgery in COVID-19-Free Surgical Pathways during the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78

Gadd45b knockout mice exhibit selective deficits in hippocampus-dependent long-term memory

Prescott T. Leach, Shane G. Poplawski, Justin W. Kenney, Barbara Hoffman, Dan A. Liebermann, Ted Abel, Thomas J. Gould, 2012, Learning and Memory on p. 319-324

Developmental effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning

George S. Portugal, Derek S. Wilkinson, Jill R. Turner, Julie A. Blendy, Thomas J. Gould, 2012, Communications in behavioral biology. Part A: [Original articles] on p. 482-494

Negative affective states and cognitive impairments in nicotine dependence

F. Scott Hall, Andre Der-Avakian, Thomas J. Gould, Athina Markou, Mohammed Shoaib, Jared W. Young, 2015, Neuroscience and Biobehavioral Reviews on p. 168-185

Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition

Xiangdang Shi, Jonathan S. Miller, Lauren J. Harper, Rachel L. Poole, Thomas J. Gould, Ellen M. Unterwald, 2014, Psychopharmacology on p. 3109-3118

NAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives

Vinay Parikh, Munir Gunes Kutlu, Thomas J. Gould, 2016, Schizophrenia Research on p. 1-15

Nicotine modulation of fear memories and anxiety: Implications for learning and anxiety disorders

Munir Gunes Kutlu, Thomas J. Gould, 2015, Biochemical Pharmacology on p. 498-511