Thomas Gould
Jean Phillips Shibley Professor and Department Head of Biobehavioral Health

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219 Biobehavioral Health
University Park, PA - tug70@psu.edu
- 814-863-7256
Research Summary
Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.
Huck Graduate Students
Huck Affiliations
- Molecular, Cellular, and Integrative Biosciences
- Neuroscience
- Neuroscience Institute
- Center for Molecular Investigation of Neurological Disorders
- Center for Brain, Behavior, and Cognition
Links
Publication Tags
Nicotine Fear Hippocampus Learning Memory Anxiety Therapeutics Conditioning (Psychology) Tobacco Use Disorder Inhibition (Psychology) Conditioning Psychological Inhibition Genetic Background Pharmaceutical Preparations Inbred Strains Mice Maintenance Rodentia Inbred C57bl Mouse Cocaine Length Genes Neurotransmitter Agents Street Drugs Ethanol Data Storage EquipmentMost Recent Papers
Genetic Influences Impacting Nicotine Use and Abuse During Adolescence: Insights from Human and Rodent Studies
L Goldberg, Thomas Gould, Brain Research Bulletin
The impact of adolescent stress on nicotine use and affective disorders in rodent models
Sean M. Mooney-Leber, Michael J. Caruso, Thomas J. Gould, Sonia A. Cavigelli, Helen M. Kamens, 2022, European Journal of Neuroscience on p. 2196-2215
Balancing Risks and Benefits of E-Cigarettes in the Real World.
J Cohen, S Krishnan-Sarin, T Eissenberg, Thomas Gould, M Berman, A Bhatnagar, T Barnett, E Soule, L Popova, Tan ASL, M Blank, P Ling, R O'Connor, 2022, American journal of public health on p. e1-e2
Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains
Sean M. Mooney-Leber, Dana Zeid, Prescilla Garcia-Trevizo, Laurel R. Seemiller, Molly A. Bogue, Stephen C. Grubb, Gary Peltz, Thomas J. Gould, 2021, Frontiers in Psychiatry
Genetic background determines behavioral responses during fear conditioning
L. R. Seemiller, S. M. Mooney-Leber, E. Henry, A. McGarvey, A. Druffner, G. Peltz, T. J. Gould, 2021, Communications in behavioral biology. Part A: [Original articles]
Terc gene cluster variants predict liver telomere length in mice
Dana Zeid, Sean Mooney-Leber, Laurel R. Seemiller, Lisa R. Goldberg, Thomas J. Gould, 2021, Cells
Genes and behavior: Animal models
Thomas J. Gould, Lisa R. Goldberg, 2021, on p. 255-262
Adult and adolescent C57BL/6J and DBA/2J mice are differentially susceptible to fear learning deficits after acute ethanol or MK-801 treatment
L. R. Seemiller, T. J. Gould, 2021, Behavioural Brain Research
Therapeutic potential of ketamine for alcohol use disorder
Stephen D. Worrell, Thomas J. Gould, 2021, Neuroscience and Biobehavioral Reviews on p. 573-589
Adolescent Stress Reduces Adult Morphine-Induced Behavioral Sensitization in C57BL/6J Mice
Helen M. Kamens, Carley N. Miller, Jasmine I. Caulfield, Dana Zeid, William J. Horton, Constanza P. Silva, Aswathy Sebastian, Istvan Albert, Thomas J. Gould, Diana Fishbein, Patricia Sue Grigson, Sonia A. Cavigelli, 2021, Frontiers in Behavioral Neuroscience
Most-Cited Papers
The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition
Sheree F. Logue, Thomas J. Gould, 2014, Pharmacology Biochemistry and Behavior on p. 45-54
Effects of drugs of abuse on hippocampal plasticity and hippocampus-dependent learning and memory
Munir Gunes Kutlu, Thomas J. Gould, 2016, Learning and Memory on p. 515-533
Developmental toxicity of nicotine
Lucinda J. England, Kjersti Aagaard, Michele Bloch, Kevin Conway, Kelly Cosgrove, Rachel Grana, Thomas J. Gould, Dorothy Hatsukami, Frances Jensen, Denise Kandel, Bruce Lanphear, Frances Leslie, James R. Pauly, Jenae Neiderhiser, Mark Rubinstein, Theodore A. Slotkin, Eliot Spindel, Laura Stroud, Lauren Wakschlag, 2017, Neuroscience and Biobehavioral Reviews on p. 176-189
Elective Cancer Surgery in COVID-19-Free Surgical Pathways during the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study
James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78
Gadd45b knockout mice exhibit selective deficits in hippocampus-dependent long-term memory
Prescott T. Leach, Shane G. Poplawski, Justin W. Kenney, Barbara Hoffman, Dan A. Liebermann, Ted Abel, Thomas J. Gould, 2012, Learning and Memory on p. 319-324
Developmental effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning
George S. Portugal, Derek S. Wilkinson, Jill R. Turner, Julie A. Blendy, Thomas J. Gould, 2012, Communications in behavioral biology. Part A: [Original articles] on p. 482-494
Negative affective states and cognitive impairments in nicotine dependence
F. Scott Hall, Andre Der-Avakian, Thomas J. Gould, Athina Markou, Mohammed Shoaib, Jared W. Young, 2015, Neuroscience and Biobehavioral Reviews on p. 168-185
Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition
Xiangdang Shi, Jonathan S. Miller, Lauren J. Harper, Rachel L. Poole, Thomas J. Gould, Ellen M. Unterwald, 2014, Psychopharmacology on p. 3109-3118
NAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives
Vinay Parikh, Munir Gunes Kutlu, Thomas J. Gould, 2016, Schizophrenia Research on p. 1-15
Nicotine modulation of fear memories and anxiety: Implications for learning and anxiety disorders
Munir Gunes Kutlu, Thomas J. Gould, 2015, Biochemical Pharmacology on p. 498-511
News Articles Featuring Thomas Gould
Nov 09, 2021
Penn State launches Center for Neurotechnology in Mental Health Research
Penn State is launching a University-wide center to bridge fundamental research to understand the brain and mind with potential clinical applications for diagnosing and treating mental health disorders.
Full Article