Thomas Gould

Jean Phillips Shibley Professor and Department Head of Biobehavioral Health

Thomas Gould

Research Summary

Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Nicotine Fear Learning Conditioning (Psychology) Hippocampus Therapeutics Memory Anxiety Corticosterone Inhibition (Psychology) Conditioning Pandemics Psychological Inhibition Sars Virus Neoplasms Cohort Studies Pharmaceutical Preparations Genetic Background Nicotinic Receptors Tobacco Use Disorder Genes Inbred C57bl Mouse Cocaine Neurotransmitter Agents Street Drugs

Most Recent Papers

Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains

Sean M. Mooney-Leber, Dana Zeid, Prescilla Garcia-Trevizo, Laurel R. Seemiller, Molly A. Bogue, Stephen C. Grubb, Gary Peltz, Thomas J. Gould, 2021, Frontiers in Psychiatry

Genetic background determines behavioral responses during fear conditioning

L. R. Seemiller, S. M. Mooney-Leber, E. Henry, A. McGarvey, A. Druffner, G. Peltz, T. J. Gould, 2021, Communications in behavioral biology. Part A: [Original articles]

Terc gene cluster variants predict liver telomere length in mice

Dana Zeid, Sean Mooney-Leber, Laurel R. Seemiller, Lisa R. Goldberg, Thomas J. Gould, 2021, Cells

Genes and behavior: Animal models

Thomas J. Gould, Lisa R. Goldberg, 2021, on p. 255-262

Adult and adolescent C57BL/6J and DBA/2J mice are differentially susceptible to fear learning deficits after acute ethanol or MK-801 treatment

L. R. Seemiller, T. J. Gould, 2021, Behavioural Brain Research

Therapeutic potential of ketamine for alcohol use disorder

Stephen D. Worrell, Thomas J. Gould, 2021, Neuroscience and Biobehavioral Reviews on p. 573-589

Adolescent Stress Reduces Adult Morphine-Induced Behavioral Sensitization in C57BL/6J Mice

Helen M. Kamens, Carley N. Miller, Jasmine I. Caulfield, Dana Zeid, William J. Horton, Constanza P. Silva, Aswathy Sebastian, Istvan Albert, Thomas J. Gould, Diana Fishbein, Patricia Sue Grigson, Sonia A. Cavigelli, 2021, Frontiers in Behavioral Neuroscience

Multigenerational nicotine exposure affects offspring nicotine metabolism, nicotine-induced hypothermia, and basal corticosterone in a sex-dependent manner

Dana Zeid, Lisa R. Goldberg, Laurel R. Seemiller, Sean Mooney-Leber, Philip B. Smith, Thomas J. Gould, 2021, Neurobehavioral toxicology

Elective Cancer Surgery in COVID-19-Free Surgical Pathways during the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78

Systems genetic analysis of nicotine withdrawal deficits in hippocampus-dependent learning

Lisa R. Goldberg, Munir Gunes Kutlu, Dana Zeid, Laurel R. Seemiller, Thomas J. Gould, 2021, Genes, Brain and Behavior

Most-Cited Papers

The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition

Sheree F. Logue, Thomas J. Gould, 2014, Pharmacology Biochemistry and Behavior on p. 45-54

Effects of drugs of abuse on hippocampal plasticity and hippocampus-dependent learning and memory

Munir Gunes Kutlu, Thomas J. Gould, 2016, Learning and Memory on p. 515-533

Developmental toxicity of nicotine

Lucinda J. England, Kjersti Aagaard, Michele Bloch, Kevin Conway, Kelly Cosgrove, Rachel Grana, Thomas J. Gould, Dorothy Hatsukami, Frances Jensen, Denise Kandel, Bruce Lanphear, Frances Leslie, James R. Pauly, Jenae Neiderhiser, Mark Rubinstein, Theodore A. Slotkin, Eliot Spindel, Laura Stroud, Lauren Wakschlag, 2017, Neuroscience and Biobehavioral Reviews on p. 176-189

Elective Cancer Surgery in COVID-19-Free Surgical Pathways during the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78

Gadd45b knockout mice exhibit selective deficits in hippocampus-dependent long-term memory

Prescott T. Leach, Shane G. Poplawski, Justin W. Kenney, Barbara Hoffman, Dan A. Liebermann, Ted Abel, Thomas J. Gould, 2012, Learning and Memory on p. 319-324

Developmental effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning

George S. Portugal, Derek S. Wilkinson, Jill R. Turner, Julie A. Blendy, Thomas J. Gould, 2012, Communications in behavioral biology. Part A: [Original articles] on p. 482-494

Negative affective states and cognitive impairments in nicotine dependence

F. Scott Hall, Andre Der-Avakian, Thomas J. Gould, Athina Markou, Mohammed Shoaib, Jared W. Young, 2015, Neuroscience and Biobehavioral Reviews on p. 168-185

Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition

Xiangdang Shi, Jonathan S. Miller, Lauren J. Harper, Rachel L. Poole, Thomas J. Gould, Ellen M. Unterwald, 2014, Psychopharmacology on p. 3109-3118

NAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives

Vinay Parikh, Munir Gunes Kutlu, Thomas J. Gould, 2016, Schizophrenia Research on p. 1-15

The duration of nicotine withdrawal-associated deficits in contextual fear conditioning parallels changes in hippocampal high affinity nicotinic acetylcholine receptor upregulation

Thomas J. Gould, George S. Portugal, Jessica M. André, Matthew P. Tadman, Michael J. Marks, Justin W. Kenney, Emre Yildirim, Michael Adoff, 2012, Neuropharmacology on p. 2118-2125