Thomas Gould

Jean Phillips Shibley Professor and Department Head of Biobehavioral Health

Thomas Gould

Research Summary

Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.

Huck Affiliations

Links

Publication Tags

Nicotine Fear Memory Hippocampus Anxiety Rodentia Learning Tobacco Use Disorder Inbred Strains Mice Pharmaceutical Preparations Inhibition (Psychology) Psychological Inhibition Genes Nicotinic Receptors Phenotype Genetic Background Cocaine Maintenance Data Storage Equipment Acetylation Alcohol Substance Related Disorders Schizophrenia Inbred Nod Mouse Neoplasms

Most Recent Publications

Chronic nicotine exposure alters sperm small RNA content in C57BL/6J mouse model

Dana Zeid, Thomas Gould, 2023, Developmental Psychobiology

Genetic differences in nicotine sensitivity and metabolism in C57BL/6J and NOD/ShiLtJ mouse strains

Laurel R. Seemiller, Lisa R. Goldberg, Phillip B. Smith, Jason Dennis, Andrew David Patterson, Thomas J. Gould, 2022, Neuropharmacology

Genetic influences impacting nicotine use and abuse during adolescence: Insights from human and rodent studies

Lisa R. Goldberg, Thomas J. Gould, 2022, Journal of Electrophysiological Techniques on p. 24-38

Inbred mouse strain differences in alcohol and nicotine addiction-related phenotypes from adolescence to adulthood

Laurel R. Seemiller, Sheree F. Logue, Thomas J. Gould, 2022, Pharmacology Biochemistry and Behavior

Balancing Risks and Benefits of E-Cigarettes in the Real World

Joanna E. Cohen, Suchitra Krishnan-Sarin, Thomas Eissenberg, Thomas J. Gould, Micah L. Berman, Aruni Bhatnagar, Tracey E. Barnett, Eric Soule, Lucy Popova, Andy S.L. Tan, Melissa D. Blank, Pamela M. Ling, Richard O'Connor, 2022, American Journal of Public Health on p. E1-E2

The impact of adolescent stress on nicotine use and affective disorders in rodent models

Sean M. Mooney-Leber, Michael *Caruso, Michael J. Caruso, Thomas J. Gould, Sonia A. Cavigelli, Helen M. Kamens, 2022, European Journal of Neuroscience on p. 2196-2215

The Effect of Acute Nicotine Administration on Human Delay Cued and Context Fear Conditioning

Alexandra N. Palmisano, Thomas J. Gould, Robert S. Astur, 2022, Experimental and Clinical Psychopharmacology

Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains

Sean M. Mooney-Leber, Dana Zeid, Prescilla Garcia-Trevizo, Laurel R. Seemiller, Molly A. Bogue, Stephen C. Grubb, Gary Peltz, Thomas J. Gould, 2021, Frontiers in Psychiatry

Genetic background determines behavioral responses during fear conditioning

L. R. Seemiller, S. M. Mooney-Leber, E. Henry, A. McGarvey, A. Druffner, G. Peltz, T. J. Gould, 2021, Communications in behavioral biology. Part A: [Original articles]

Genes and behavior: Animal models

Thomas J. Gould, Lisa R. Goldberg, 2021, on p. 255-262

Most-Cited Papers

The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition

Sheree F. Logue, Thomas J. Gould, 2014, Pharmacology Biochemistry and Behavior on p. 45-54

Effects of drugs of abuse on hippocampal plasticity and hippocampus-dependent learning and memory: Contributions to development and maintenance of addiction

Munir Kutlu, Thomas J. Gould, 2016, Learning and Memory on p. 515-533

Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products

Lucinda England, Kjersti Aagaard, Michele Bloch, Kevin Conway, Kelly Cosgrove, Rachel Grana, Thomas J. Gould, Dorothy Hatsukami, Frances Jensen, Denise Kandel, Bruce Lanphear, Frances Leslie, James Pauly, Jenae Neiderhiser, Mark Rubinstein, Theodore Slotkin, Eliot Spindel, Laura Stroud, Lauren Wakschlag, 2017, Neuroscience and Biobehavioral Reviews on p. 176-189

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78

Negative affective states and cognitive impairments in nicotine dependence

F. Scott Hall, Andre Der-Avakian, Thomas J. Gould, Athina Markou, Mohammed Shoaib, Jared W. Young, 2015, Neuroscience and Biobehavioral Reviews on p. 168-185

Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition

Xiangdang Shi, Jonathan S. Miller, Lauren J. Harper, Rachel L. Poole, Thomas J. Gould, Ellen M. Unterwald, 2014, Psychopharmacology on p. 3109-3118

Nicotine modulation of fear memories and anxiety: Implications for learning and anxiety disorders

Munir Gunes Kutlu, Thomas J. Gould, 2015, Biochemical Pharmacology on p. 498-511

NAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives

Vinay Parikh, Munir Gunes Kutlu, Thomas J. Gould, 2016, Schizophrenia Research on p. 1-15

17β-estradiol regulates histone alterations associated with memory consolidation and increases Bdnf promoter acetylation in middle-aged female mice

Ashley M. Fortress, Jaekyoon Kim, Rachel L. Poole, Thomas J. Gould, Karyn M. Frick, 2014, Learning and Memory on p. 457-467

Targeted deletion of the mouse α2 nicotinic acetylcholine receptor subunit gene (Chrna2) potentiates nicotine-modulated behaviors

Shahrdad Lotfipour, Janet S. Byun, Prescott Leach, Christie D. Fowler, Niall P. Murphy, Paul J. Kenny, Thomas J. Gould, Jim Boulter, 2013, Journal of Neuroscience on p. 7728-7741