126 People Results for the Tag: Rna

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Michael Axtell

Distinguished Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets

Laura Carrel

Associate Professor of Biochemistry and Molecular Biology
Genetic, epigenetic, and genomic regulation of expression on the mammalian X chromosome.

Surinder Chopra

Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.

Jessica Conway

Associate Professor of Mathematics
Viral infection dynamics and interplay with therapies for elimination or control

Center for Infectious Disease Dynamics

Susan Hafenstein

Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.

Center for Infectious Disease Dynamics

Mark Hedglin

Assistant Professor of Chemistry; Assistant Professor of Biochemistry and Molecular Biology
Deciphering how efficient and faithful replication of the human genome is achieved within the highly-complex, dynamic, and reactive environment of the nucleus. Identifying pathways for genomic instability in humans, identifying novel oncogenic drug targets, developing better chemotherapeutic treatments for human cancers caused by genomic instability.

Kevin Hockett

Huck Early Career Chair; Assistant Professor of Microbial Ecology
Biological Control, Biology and Ecology of Plant-Microbe and Plant-Environment Interactions, Microbial Ecology and Population Biology Faculty

Center for Infectious Disease Dynamics

Joyce Jose

Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.

Center for Infectious Disease Dynamics

Andrey Krasilnikov

Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes

Aimin Liu

Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.

Sally Mackenzie

Director of the Plant Institute; Huck Chair of Functional Genomics; Professor of Biology and of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Elizabeth McGraw

Professor and Huck Scholar in Entomology
The genetics of vector, pathogen and symbiont interactions.

Center for Infectious Disease Dynamics

Timothy McNellis

Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.

Jason Rasgon

Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.

Center for Infectious Disease Dynamics

Tanya Renner

Assistant Professor of Entomology
Evolution of chemical and structural defense. Molecular evolution, evolutionary genomics, and transcriptomics. Origins and evolution of carnivorous plants.

Mingfu Shao

Assistant Professor of Computer Science and Engineering
Our research interests are designing algorithms and developing methods for solving the various challenging problems in biology using combinatorial optimization and machine learning approaches. Current research topics include: transcript assembly, RNA-seq quantification, single-cell RNA-seq, computational cancer biology, genome rearrangements, protein folding.

Cooduvalli Shashikant

Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.

Troy Sutton

Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research

Center for Infectious Disease Dynamics

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Monica Medina

Professor of Biology

Center for Infectious Disease Dynamics

Moriah Szpara

Associate Professor of Biochemistry & Molecular Biology and Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.

Center for Infectious Disease Dynamics

Peter Hudson

Former Director, Huck Institutes of the Life Sciences; Willaman Professor of Biology
Population dynamics of infectious diseases in wildlife and the dynamics of parasite community structure.

Center for Infectious Disease Dynamics

Scott Lindner

Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).

Center for Infectious Disease Dynamics

Suresh Kuchipudi

Huck Chair in Emerging Infectious Diseases; Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions

Center for Infectious Disease Dynamics

Bhushan Jayarao

Professor of Veterinary and Biomedical Sciences

Cristina Rosa

Associate Professor of Plant Pathology & Environmental Microbiology
Plant Virology, interaction of plant viruses with their insects as vectors and with their plant hosts. Virus evolution, exploration of plant viromes, viral co-infections, effect of climate change on viral resistant breaking strains. Use of nanotechnologies for virus detection and virus disease management.

Dajiang Liu

Co-Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Professor of Public Health Sciences and Biochemistry and Molecular Biology
Developing novel methods to analyze very large scale datasets in order to identify genes that are responsible for disease, understand the disease mechanism, and gain clinical insights.

David Gilmour

Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Douglas Cavener

Huck Distinguished Chair in Evolutionary Genetics; Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Fang (Rose) Zhu

Assistant Professor of Entomology
Understanding the mechanisms and evolution of insects’ adaptation to chemical stresses in their environment.

Francisco Diaz

Director of the Center for Reproductive Health and Biology; Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Howard Salis

Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.

John Regan

Professor of Civil and Environmental Engineering
Biological treatment processes, molecular microbial ecology, bioenergy production.

Joseph Reese

Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.

Joyce Sakamoto

Assistant Research Professor

Center for Infectious Disease Dynamics

Kateryna Makova

Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.

Pak Kin Wong

Professor of Biomedical Engineering, Mechanical Engineering, and Surgery

Paul Babitzke

Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins

Philip Bevilacqua

Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth

Ramesh Ramachandran

Professor of Molecular Endocrinology
The influence of hypothalamic neurotransmitters, hormones, and their receptors on avian reproduction.

Reyad Elbarbary

Assistant Professor of Orthopaedics
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.

Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Wansheng Liu

Professor of Genomics
Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.

Weihua Guan

Assistant Professor of Electrical Engineering

Hyunwook Lee

Postdoctoral Scholar - Hafenstein Lab

Center for Infectious Disease Dynamics

Kurt Vandegrift

Associate Professor
Disease ecology with an emphasis on the population dynamics of zoonotic parasites and reservoir hosts.

Center for Infectious Disease Dynamics

David Kennedy

Assistant Professor of Biology
Ecology and evolution of infectious diseases, with particular interest in how disease dynamics influence pathogen emergence, virulence evolution, and drug or vaccine resistance.

Center for Infectious Disease Dynamics

Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Sally Assmann

Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.

James Connor

Distinguished Professor and Vice Chair of Neurosurgery
Iron transport and toxicity in neurodegenerative diseases/oxidative cell injury.

Richard Cyr

Professor Emeritus of Biology

Zhi-Chun Lai

Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Claire Thomas

Associate Professor of Biology and of Biochemistry and Molecular Biology
Roles of the cytoskeleton at the cell membrane in epithelial cells, including issues of cell polarity and adhesion, cell signaling, and morphogenesis.

Kristin Eckert

Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.

Donald Bryant

Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.

Wayne Curtis

Professor of Chemical Engineering
Regulation and signal transduction in plant secondary metabolism. Phytoremediation of hydrocarbons. Commercial chemical production in plants and plant tissue culture.

Mark Guiltinan

J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.

Craig Meyers

Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.

Leslie Parent

Professor of Medicine and Microbiology & Immunology

Laura Klein

Professor of Biobehavioral Health
Biobehavioral effects of stress on drug abuse; sex differences in neuroendocrine and behavioral stress responses; nicotine regulation of stress reactivity.

Costas Maranas

Donald B. Broughton Professor of Chemical Engineering
Computational studies of metabolism and gene regulation.

David Huff

Professor of Turfgrass Breeding and Genetics
Population genetics. Plant evolution and ecology. Crop improvement. Physiological tolerance to biotic and abiotic stress.

Pamela Mitchell

Emeritus Associate Professor of Biology

Sergei Grigoryev

Professor of Biochemistry and Molecular Biology

Sarah Ades

Professor of Biochemistry & Molecular Biology; Associate Dean of The Graduate School
Signal transduction and antibiotic-induced stress responses in bacteria.

Thomas Spratt

Associate Professor or Biochemistry

Arun Sharma

Associate Professor of Pharmacology

Jianming Hu

Professor of Microbiology and Immunology

Mary Ann Bruns

Professor of Soil Microbiology and Biogeochemistry
Compositions and functions of microbiomes in agriculture, ecological restoration, and engineered systems for ecosystem service provision and climate change adaptation

John Wills

Distinguished Professor of Microbiology and Immunology

Siela Maximova

Research Professor of Plant Biotechnology Co-Director, Endowed Program in the Molecular Biology of Cocoa
Molecular basis of plant-pathogen and plant-endophyte interactions. Biotechnology of tree crops. Development of sustainable energy crops.

Jeffery Sample

Professor of Microbiology

Hong-Gang Wang

Professor of Pharmacology

James Broach

Distinguished Professor and Chair of Biochemistry and Molecular Biology

Xiaojun (Lance) Lian

Associate Professor of Biomedical Engineering
Human Stem Cell Engineering; Genome Editing via CRISPR-Cas9; Epigenome Editing and Epigenetics.

Terrence Bell

Assistant Professor of Phytobiomes
Soil and root-associated microbiomes, microbiome assembly, microbiome manipulation, disturbance.

Neela Yennawar

Director, X-Ray Crystallography and Automated Biological Calorimetry Core Facilities; Research Professor
Biological calorimetry, protein characterization, molecular modeling, X-ray crystallography, and small-angle X-ray scattering.

Gang Ning

Director, Microscopy Core Facility; Research Professor
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.

Center for Infectious Disease Dynamics

Nikolay Dokholyan

G. Thomas Passananti Professor of Pharmacology; Professor of Biochemistry and Molecular Biology
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.

Center for Infectious Disease Dynamics

Matthew Jones

Research Assistant - Read Lab and McGraw Lab

Center for Infectious Disease Dynamics

Sarah Craig

Assistant Research Professor

Yifei Huang

Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.

Joseph Cotruvo

Associate Professor of Chemistry
Biochemistry and chemical biology to uncover and understand new metal and redox biology. We are particularly interested in applications to infectious disease, bioenergy, and cancer biology.

Katsuhiko Murakami

Professor of Biochemistry and Molecular Biology
Structural and Mechanistic Enzymology of Prokaryotic RNA Polymerases

Raymond Hohl

University Professor of Oncology; Professor of Pharmacology

Bruce Stanley

Director of the Section of Research Resources, Hershey

Kari Peter

Assistant Research Professor of Tree Fruit Pathology

Josephine Wee

Assistant Professor of Food Science

Gary Thompson

Associate Dean for Research and Graduate Education, College of Agricultural Sciences; Director, PA Agricultural Experiment Station

Howard Fescemyer

Assistant Research Professor

Emily Weinert

Associate Professor of Biochemistry and Molecular Biology
The mechanisms by which bacteria sense and respond to the environment, as well as how these signaling proteins/pathways affect competition, host colonization, and pathogenesis.

Sung Hyun Cho

Assistant Research Professor, Cryo-Electron Microscopy Core Facility

Stephen Benkovic

Evan Pugh University Professor and Eberly Chair in Chemistry

Squire Booker

Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.

Will Dearnaley

Technical Director, Dept. of Biomedical Engineering & Center for Structural Oncology

Justin Silverman

Assistant Professor of Information Sciences and Technology
Statistical methods for the analysis of biomedical data (or any other interesting data/questions)

Center for Infectious Disease Dynamics

Tae Hyun Kim

Huck Early Career Chair; Assistant Professor of Avian Biology
Improving poultry health by applying modern genetic approaches including gene editing. Particular focus on identifying key genes and regulatory elements associated with improved economic traits.

Ganesh Srinivasan Anand

Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.

Center for Infectious Disease Dynamics

Parisa Kalantari

Assistant Professor of Immunology
Host-parasite interactions using Schistosoma mansoni-induced liver inflammation in mouse models. Modulation of immune responses by the parasite as well as the role of inflammasomes in inducing schistosomiasis.

Christian Huber

Assistant Professor of Biology
How evolutionary mechanisms such as mutation, recombination, and natural selection shape genetic diversity and the variability between individuals and species.

Melanie McReynolds

Huck Early Career Chair in Biochemistry and Molecular Biology; Assistant Professor of Biochemistry and Molecular Biology
The biochemistry behind aging and its intersection with stress, with the long-term goal of identifying strategies that promote healthier aging.

Megan Marshall

Associate Teaching Professor of Agricultural and Biological Engineering

Ilias Georgakopoulos-Soares

Assistant Professor
The development and implementation of new computational methods in genomics and molecular biology, with the aim of identifying genetic biomarkers for the diagnosis, monitoring, and treatment of human diseases, including bacterial and viral infections and of aging-associated diseases including neurodegenerative diseases and cancer.