67 People Results for the Tag: Phosphorylation

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Laura Carrel

Associate Professor of Biochemistry and Molecular Biology
Chromosome structure and function Genome organization Long-range control of gene expression Heterochromatin formation Epigenetic role in human disease Genetics and genomics of X chromosome inactivation in human and mouse

Adam Glick

Associate Chair, Molecular Cellular and Integrative Biosciences; Emphasis Area Representative, Cancer Biology; Professor of Molecular Toxicology and Carcinogenesis;
The role of Transforming Growth Factor-beta in cutaneous inflammation and cancer development, and how the immune system responds to epithelial cells with activated oncogenes such as Ras. Signaling pathways that regulate senescence of premalignant epithelial cells and how cells escape from oncogene-induced senescence.

Center for Infectious Disease Dynamics

Tae-Hee Lee

Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin

Aimin Liu

Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.

Yingwei Mao

Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.

Anthony Schmitt

Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.

Song Tan

Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.

Yinong Yang

Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.

Jesse Lasky

Assistant Professor of Biology
Ecological and evolutionary genomics, genetic and ecophysiological basis of adaptation to environmental stress, evolutionary ecology of biological complexity.

Center for Infectious Disease Dynamics

Arthur Lesk

Professor of Biochemistry and Molecular Biology

Bernhard Luscher

Emphasis Area Representative, Neurobiology; Director of the Center for Molecular Investigation of Neurological Disorders; Professor of Biology, Biochemistry and Molecular Biology
Function of GABAergic synaptic transmission in health and disease, with emphasis of stress based psychiatric disorders such as major depressive disorders and mechanisms of antidepressant drug action

Cheng Dong

Advisor for the Center for Mathematics of Living and Mimetic Matter

David Gilmour

Professor of Molecular and Cell Biology
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Douglas Cavener

Professor and Verne M. Willaman Dean, Eberly College of Science; Chair of the Genetics Program
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.

Francisco Diaz

Associate Professor of Reproductive Biology
Ovarian physiology. Role of SMAD-mediated signaling in follicular and female germ cell (oocyte) development.

Lu Bai

Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.

Pamela Giblin

Professor of Immunology
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Reyad Elbarbary

Assistant Professor of Orthopaedics
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.

Rudolf Schilder

Assistant Professor of Entomology and Biology
Comparative & ecological physiology of insect and mammalian locomotion.

Scott Showalter

Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Biophysical Chemistry applied to solution NMR spectroscopy of partially disordered proteins. NMR studies of protein dynamics coupled with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion.

Shaun Mahony

Assistant Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity

James Connor

Distinguished Professor and Vice Chair of Neurosurgery
Iron transport and toxicity in neurodegenerative diseases/oxidative cell injury.

B. Tracy Nixon

Professor of Biochemistry and Molecular Biology
Structural and functional basis of cellulose synthesis. Using Physcomitrella patens and other organisms as model systems, we are learning how plants make cellulose for building new cell wall. The studies use methods of molecular biology and cryoEM to characterize the enzyme as a monomer, and when it assembles into its larger 'Cellulose Synthase Complex '(CSC for short). The aim is to understand cellulose synthesis to explain fundamentals of cell wall biology in plants, and to enable manipulation of its synthesis for applications in fields of bioenergy and materials.

Franklin Pugh

Director of the Center for Eukaryotic Gene Regulation; Willaman Professor in Molecular Biology
Biochemistry and genomics of eukaryotic transcription regulation.

Jack Vanden Heuvel

Director of the Center for Excellence in Nutrigenomics; Professor of Molecular Toxicology
Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.

Richard Frisque

Professor of Molecular Virology

Sarah Bronson

Associate Professor of Cellular and Molecular Physiology

Regina Vasilatos-Younken

Dean of the Graduate School; Professor of Poultry Science, Endocrine Physiology, and Nutrition
Role of endocrine and metabolic factors in the regulation of muscle and adipose tissue growth.

Ralph Keil

Associate Professor of Biochemistry and Molecular Biology

Donna Korzick

Chair, Intercollege Graduate Degree Program in Integrative and Biomedical Physiology; Professor of Physiology and Kinesiology
My research is focused on aging, post-menopausal women, and cardiac ischemia reperfusion injury using animal models. We are particularly interested in the effects of estrogen deficiency on mitochondrial regulation of cell survival following myocardial infarction. Multiple levels of inquiry addressing mitochondrial quality control regulation and immune signaling is emphasized.

Todd Schell

Professor Microbiology & Immunology

Jong Yun

Professor of Pharmacology

Shantu Amin

Professor of Pharmacology

Arun Sharma

Associate Professor of Pharmacology

Jianming Hu

Professor of Microbiology and Immunology

Colin Barnstable

Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

Jeffery Sample

Professor of Microbiology

Rosalyn Irby

Associate Professor of Cancer Research

Jin-Ming Yang

Professor of Pharmacology

Hong-Gang Wang

Professor of Pharmacology

Kathleen Mulder

Professor of Biochemistry and Molecular Biology

Ying Gu

Associate Professor of Biochemistry and Molecular Biology
Mechanism of cellulose biosynthesis in higher plants. Genetic modification of plant cell wall to scale-up biofuel production.

James Broach

Professor and Chair, Biochemistry and Molecular Biology

Sinisa Dovat

Associate Professor of Pediatric Hematology and Oncology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.

Gustavo Nader

Associate Professor of Kinesiology
Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.

Thomas Gould

Jean Phillips Shibley Professor and Department Head of Biobehavioral Health
Using genetic, pharmacological, behavioral, and molecular biological techniques to study the neurobiology of learning and memory and the effects of addiction on it.

Tatiana Laremore

Director, Proteomics and Mass Spectrometry Core Facility

Gang Ning

Director, Microscopy Core Facility
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.

Center for Infectious Disease Dynamics

Nikolay Dokholyan

G. Thomas Passananti Professor
We are a translational systems research group in the Pharmacology at the Penn State College of Medicine. Our laboratory focuses on understanding etiologies of human diseases, such as cystic fibrosis (CF), amyotrophic lateral sclerosis (ALS), and pain conditions, such as hyperalgesia.

Center for Infectious Disease Dynamics

Elizabeth Proctor

Assistant Professor of Neurosurgery, Pharmacology, Biomedical Engineering, and Engineering Science & Mechanics
Systems biology of complex disease. Integration of heterogeneous data types across length scales.

Mauricio Pontes

Assistant Professor of Pathology

Tami Mysliwiec

Associate Professor of Biology

Guy Townsend

Assistant Professor of Biochemistry and Molecular Biology