181 People Results for the Tag: Genome
Istvan Albert
Research Professor of Bioinformatics
Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.
Center for Infectious Disease Dynamics
Michael Axtell
Professor of Biology
Discovery and characterization of plant microRNAs and siRNAs. Functions of microRNAs and siRNAs in the evolution of plant development. Genomics and bioinformatics of microRNAs, siRNAs, and their targets
John Carlson
Professor of Molecular Genetics; Director, Schatz Center for Tree Molecular Genetics
Genome mapping, including genetic linkage mapping, molecular cytogenetics; studies of genetic diversity in forests.
Laura Carrel
Associate Professor of Biochemistry and Molecular Biology
Genetic, epigenetic, and genomic regulation of expression on the mammalian X chromosome.
Surinder Chopra
Professor of Maize Genetics
Regulation of flavonoid biosynthesis during plant development and plant-pathogen interaction. Epigenetic regulation and allele specific patterns.
Arthur Berg
Associate Professor of Public Health Sciences and Statistics
Unlocking the mysteries of DNA and its connection to human health.
Claude dePamphilis
Director of the Center for Parasitic and Carnivorous Plants; Huck Distinguished Chair in Plant Biology and Evolutionary Genomics; Professor of Biology
Genomics, bioinformatics, and molecular evolution. Origin and diversification of flowers and developmental pathways. Comparative genomics of plants, organelles, and plant gene families. Genomics, evolution, and functional biology of parasitic plants.
Matthew Ferrari
Director of the Center for Infectious Disease Dynamics; Huck Career Development Professor; Associate Professor of Biology
Public Health, Quantitative Epidemiology, Population Ecology, Statistics, Computational and Mathematical Biology
Center for Infectious Disease Dynamics
Santhosh Girirajan
Associate Professor of Biochemistry & Molecular Biology; Associate Professor of Anthropology
Understanding the genetic basis of neurodevelopmental disorders.
Susan Hafenstein
Director of the Center for Structural Biology; Huck Chair of Structural Virology; Professor of Biochemistry and Molecular Biology
Using a structural approach to learn more about viral infectivity, tropism, evolution and pathogenicity. Developing approaches to visualize critical events that cause a break from the regular symmetry of the virus, including packaging of the genome, receptor usage, antibody interactions and uncoating of the viral genome during the final stages of infection.
Center for Infectious Disease Dynamics
Molly Hall
Dr. Frances Keesler Graham Early Career Professor; Assistant Professor of Veterinary and Biomedical Sciences
Building tools to elucidate the complex genetic and environmental underpinnings of human disease. Integrating genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status.
Wendy Hanna-Rose
Professor of Biochemistry and Molecular Biology; Head of BMB
Molecular Genetics of Metabolism and Development in C. elegans
Heather Hines
Associate Professor of Biology and Entomology
Applies genomic, transcriptomic, phylogenomic, and bioinformatic approaches to study the evolution and genetics of diverse traits in bees and wasps. This includes study of mimetic color diversification, plant gall induction, novel morphologies, speciation, and social evolution.
Timothy Jegla
Emphasis Area Representative, Molecular and Evolutionary Genetics; Associate Professor of Biology
Functional evolution of eukaryotic ion channels and evolution of neuronal signaling and cell structure.
Joyce Jose
Assistant Professor of Biochemistry & Molecular Biology
Virus-host interactions involved in the pathogenesis of alphaviruses and flaviviruses. Analysis of virus induced structures and cytoskeletal modifications in mammalian host and insect vector using high-resolution live cell imaging and electron microscopy. Viral determinants of neurotropism, encephalitis, transmission and persistence in BSL-3 pathogens.
Center for Infectious Disease Dynamics
Girish Kirimanjeswara
Associate Professor of Veterinary and Biomedical Science
Establishing the Virulence Factors
Center for Infectious Disease Dynamics
Andrey Krasilnikov
Associate Professor of Biochemistry and Molecular Biology
Structural biology of RNA and RNA-protein complexes
Tae-Hee Lee
Professor of Chemistry
Single-molecule biophysics of the nucleosome and chromatin
Qunhua Li
Associate Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Statistics
Developing statistical and computational methods for analyzing complex omics data and improving quality and reproducibility of high-throughout data
Aimin Liu
Associate Professor of Biology
Biogenesis and function of cilia in mammalian embryonic development.
Hong Ma
Huck Distinguished Research Professor of Plant Molecular Biology; Professor of Biology
Plant development under favorable and stressful conditions; phylogeny and evolutionary biology of plant groups containing major crops and ecologically important species.
Sally Mackenzie
Huck Chair of Functional Genomics; Professor of Biology and of Plant Science
Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.
Jennifer Macalady
Director of the Ecology Institute; Professor of Geosciences
Microbial interactions with earth materials: soils, sediments, solutes, atmospheric gases, minerals, and rocks. Early evolution of Earth’s biosphere, including photosynthesis and sulfur cycling. Microbial ecology, environmental omics, microbial biogeography.
Center for Infectious Disease Dynamics
Yingwei Mao
Associate Professor of Biology
Regulation of neurogenesis using cellular and mouse models; analysis of abnormal neural progenitor cell (NPC) proliferation and its relationship to mental illnesses; identification of drugs that can reverse mouse models of psychiatric disorders.
Timothy McNellis
Associate Professor of Plant Pathology & Environmental Microbiology
Genetics, molecular biology and physiology of plant interactions with phytopathogenic bacteria. Signal transduction events involved in plant disease resistance. Genetic control of plant hypersensitive cell death.
Paul Medvedev
Director of the Center for Computational Biology and Bioinformatics; Associate Professor of Computer Science and Engineering; Associate Professor of Biochemistry and Molecular Biology
Please see the researcher's homepage at http://medvedevgroup.com
Anton Nekrutenko
Professor of Biochemistry and Molecular Biology
Evolution of overlapping reading frames in eukaryotic genomes.
George Perry
Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Anthropology and Biology
Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.
Center for Infectious Disease Dynamics
Jason Rasgon
Professor of Entomology and Disease Epidemiology
Integrating population biology, ecology, molecular tools and theory to address fundamental and applied questions related to vector arthropods and the pathogens they transmit.
Center for Infectious Disease Dynamics
Melissa Rolls
Chair, Intercollege Graduate Degree Program in Molecular, Cellular and Integrative Biosciences; Co-Director of the Center for Cellular Dynamics; Paul Berg Professor of Biochemistry and Molecular Biology
Subcellular compartmentalization of neurons. The cellular basis of neuronal polarity and neuronal responses to injury including degeneration and regeneration.
Steven Schiff
Director of the Center for Neural Engineering; Brush Chair Professor of Engineering; Professor of Neurosurgery; Professor of Engineering Science and Mechanics
Neural engineering, neurosurgery, epilepsy, Parkinsons Disease, wave mechanics, brain machine interfaces, EEG, electrical fields, and control theory.
Center for Infectious Disease Dynamics
Anthony Schmitt
Professor of Molecular Immunology and Infectious Diseases
The process of paramyxovirus particle formation by budding: identifying and characterizing viral proteins used in budding, and learning how these manipulate host budding machinery to allow virus release.
Mingfu Shao
Assistant Professor of Computer Science and Engineering
Our research interests are designing algorithms and developing methods for solving the various challenging problems in biology using combinatorial optimization and machine learning approaches. Current research topics include: transcript assembly, RNA-seq quantification, single-cell RNA-seq, computational cancer biology, genome rearrangements, protein folding.
Cooduvalli Shashikant
Former Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics
Developmental and evolutionary aspects of regulation of patterning genes.
Troy Sutton
Assistant Professor of Veterinary and Biomedical Sciences
Animal models of influenza; Airborne transmission of influenza viruses; Evolution of pandemic influenza viruses; Highly pathogenic avian influenza; Development of live-attenuated influenza vaccine platforms; High containment BSL3+ research
Center for Infectious Disease Dynamics
Song Tan
Director of the Center for Eukaryotic Gene Regulation; Professor of Biochemistry and Molecular Biology
Structural biology of eukaryotic gene regulation.
David Vandenbergh
Professor of Biobehavioral Health
Genetics of addiction in human populations and its neurobiological basis in animal models.
Yinong Yang
Professor, Department of Plant Pathology and Environmental Microbiology
Signal perception and transduction in rice-pathogen interactions. Molecular and genomic strategies for increasing disease resistance and drought tolerance in cereal crops.
Anne Vardo-Zalik
Assistant Professor of Biology
The ecology and population genetics of malaria parasites and their vectors
Center for Infectious Disease Dynamics
David R Hunter
Professor of Statistics, Department Head
I work on statistical models for networks, mixture models, and certain optimization algorithms called MM algorithms. A full list of papers and related work, such as software, may be found at http://sites.stat.psu.edu/~dhunter/.
Center for Infectious Disease Dynamics
Edward Dudley
Professor of Food Science; Director of E. coli Reference Center
Mechanisms driving toxin production in Shiga-toxigenic Escherichia coli; use of genome sequencing to track pathogen transmission during foodborne outbreaks
Center for Infectious Disease Dynamics
Iliana Baums
Professor of Biology
Molecular ecology and evolution of reef invertebrates.
Center for Infectious Disease Dynamics
Ira Ropson
Associate Professor of Biochemistry and Molecular Biology
Folding, stability and function of proteins.
Jasna Kovac
Lester Earl and Veronica Casida Career Development Professor of Food Safety; Assistant Professor of Food Science
Integrating epidemiological, microbiological, molecular and omics methods to better understand microbial pathogenic potential, antimicrobial resistance, and epidemiology of foodborne pathogens.
Center for Infectious Disease Dynamics
Jesse Lasky
Associate Professor of Biology
Ecological and evolutionary genomics, genetic and ecophysiological basis of adaptation to environmental stress, evolutionary ecology of biological complexity.
Center for Infectious Disease Dynamics
Maciej F Boni
Associate Professor of Biology
Human influenza epidemiology and evolution, evaluating population-level malaria treatment strategies with individual-based microsimulation models, phylogenetic analysis of avian influenza evolution in southern Vietnam, economic epidemiology of avian influenza, evaluating population-level efficacy of a potential dengue vaccine with mathematical models
Center for Infectious Disease Dynamics
Moriah Szpara
Associate Professor of Biochemistry & Molecular Biology and Biology
How genetic variation influences the outcomes of viral infection, particularly for neurotropic viruses such as herpes simplex virus 1 (HSV-1) and HSV-2, using high-throughput sequencing, comparative genomics, neuronal cultures, and genetic manipulation of both host and pathogen.
Center for Infectious Disease Dynamics
Murali Haran
Associate Professor of Statistics
Statistical computing (Markov chain Monte Carlo algorithms); spatial models (Gaussian random field models); methods for complex computer models; interdisciplinary collaborations in environmental sciences, climate science, disease modeling, ecology
Center for Infectious Disease Dynamics
Naomi Altman
Professor Emeritus of Statistics
Bioinformatics, gene expression analysis, functional genomics and gene clustering, experimental design, multiple testing, functional data analysis and nonparametric smoothing.
Patricia A. Dunn
Senior Research Associate, Avian Pathologist and Field Investigator
Center for Infectious Disease Dynamics
Scott Lindner
Associate Professor of Biochemistry & Molecular Biology, Co-Director, Center for Malaria Research
Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium spp.).
Center for Infectious Disease Dynamics
Suresh Kuchipudi
Huck Chair in Emerging Infectious Diseases, Clinical Associate Professor; Section Head Mammalian Virology & Immunology
Diagnostic Virology & Serology -Zoonotic and Emerging Viruses -Negative strand RNA viruses -Avian and Mammalian influenza -Immune responses to viruses -Viral pathogenesis Quantitative-omics approach to virus-host interactions
Center for Infectious Disease Dynamics
Andrew Deans
Professor of Entomology, Director of the Frost Entomological Museum
Carolee Bull
Director of the Microbiome Center; Professor of Plant Pathology; Bacterial Systematics Head, Department of Plant Pathology and Environmental Microbiology
Bacterial systematics, epidemiology, and population biology of bacterial plant pathogens and biological control agents to develop alternatives to synthetic chemicals for plant disease management
Dajiang Liu
Associate Professor of Public Health Science
Developing novel methods to analyze very large scale datasets in order to identify genes that are responsible for disease, understand the disease mechanism, and gain clinical insights.
Douglas Cavener
Huck Distinguished Chair in Evolutionary Genetics; Professor of Biology; Former Dean, Eberly College of Science
Regulation of protein synthesis and control of translation initiation of mRNAs in higher eukaryotes and the evolution of tissue specific transcriptional regulation.
Francesca Chiaromonte
Director of the Genome Sciences Institute; Huck Chair in Statistics for the Life Sciences; Professor of Statistics
Developing methods for the analysis of large, high-dimensional and complex data.
Howard Salis
Associate Professor of Chemical Engineering; Associate Professor of Agricultural and Biological Engineering
Engineering microorganisms for applications in synthetic biology and metabolic engineering.
Joseph Reese
Professor of Biochemistry and Molecular Biology
Gene regulation in cell cycle and DNA damage control; regulation of DNA damage-induced transcription.
Kateryna Makova
Director of the Center for Medical Genomics; Professor of Biology
Molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics.
Lu Bai
Associate Professor of Biochemistry and Molecular Biology; Associate Professor of Physics
Single cell / single molecule study of chromatin and gene regulation.
Paul Babitzke
Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
Regulation of gene expression by RNA structure and RNA-binding proteins
Philip Bevilacqua
Co-Director, Center for RNA Molecular Biology; Distinguished Professor of Chemistry and of Biochemistry and Molecular Biology
RNA folding in vivo and genome-wide; RNA regulation of gene expression; Ribozyme Mechanism; roles RNA may have played in the emergence of life on early earth
Reyad Elbarbary
Assistant Professor of Orthopaedics
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.
Richard Ordway
Professor of Molecular Neuroscience and Genetics
Genetic analysis of neural function.
Ross Hardison
Associate Director of the Genome Sciences Institute; T. Ming Chu Professor of Biochemistry and Molecular Biology
Regulation of gene expression during development.
Shaun Mahony
Associate Professor of Biochemistry & Molecular Biology
We apply neural networks and other machine learning approaches to understand how transcription factors control cellular identity
Stephen Schaeffer
Professor of Biology
Population Genetics and Genomics of Chromosomal Rearrangements in Drosophila
Wansheng Liu
Professor of Genomics
Functional annotation of farm animal genomes, structure and function of mammalian sex (X and Y) chromosome, spermatogenesis and male fertility.
Robab Katani
Assistant Research Professor of Global Health
Global health security, infectious diseases, and host-pathogen dynamics, as well as expertise in the enhancement of capabilities in the Low- and Middle-Income Countries, including Tanzania and India.
Center for Infectious Disease Dynamics
David Kennedy
Assistant Professor of Biology
Ecology and evolution of infectious diseases, with particular interest in how disease dynamics influence pathogen emergence, virulence evolution, and drug or vaccine resistance.
Center for Infectious Disease Dynamics
Sally Assmann
Waller Professor of Biology
Molecular biology of plant G-proteins and kinases. Phytohormone regulation of signal transduction and RNA processing. Second messenger regulation of ion channels in plant cells.
Teh-hui Kao
Chair, Intercollege Graduate Degree Program in Plant Biology; Distinguished Professor of Biochemistry and Molecular Biology
Molecular, biochemical, and structural bases of the S-RNase-based self-incompatibility system in flowering plants. F-box protein-mediated ubiquitination and degradation of proteins.
Zhi-Chun Lai
Emphasis Area Representative, Cell and Developmental Biology; Professor of Biology, Biochemistry and Molecular Biology
Signal Transduction, Growth Control, and Cancer Genetics
Kristin Eckert
Professor of Pathology and Laboratory Medicine and of Biochemistry and Molecular Biology
Mechanisms of human cell mutagenesis and repetitive DNA replication in relation to genome evolution.
Donald Bryant
Ernest C. Pollard Professor of Biotechnology; Professor of Biochemistry and Molecular Biology
Photosynthesis, structure-function relationships of proteins, gene regulation, and microbial physiology. Cyanobacteria and green sulfur bacteria. Genomics of photosynthetic bacteria.
Ming Tien
Professor of Biochemistry & Molecular Biology
Characterization and biochemical analysis of cellulose synthesis in a variety of organisms. Mechanism and regulation of fungal degradation of lignin. Dissimilatory Iron reduction.
Kathleen Brown
Professor of Plant Stress Biology
Regulation of root development. Root responses to edaphic stress. Identification and genetic mapping of traits for adaptation to edaphic stress.
Majid Foolad
Professor of Plant Genetics
Genetic characterization of resistance/tolerance to biotic/abiotic stresses, and genes/QTLs contributing to tomato fruit quality. Investigation of genes/QTLs for directed crop improvement and germplasm enhancement. Tomato cultivar development & release.
Mark Guiltinan
J. Franklin Styer Professor of Horticultural Botany; Professor of Plant Molecular Biology; Director, Endowed Program in the Molecular Biology of Cocoa
Plant functional genomics, metabolomics and biotechnology. Identification of key genes for disease resistance and important traits in the tree crop Theoboma cacao, the Chocolate tree.
Jonathan Lynch
Director of the Center for Root and Rhizosphere Biology; Distinguished Professor of Plant Nutrition
Plant adaptation to nutrient and water stress. Global change. World hunger. Root biology.
Keith Cheng
Distinguished Professor of Pathology and Laboratory Medicine, of Biochemistry and Molecular Biology, and of Pharmacology
Computational phenomics, image informatics, and "Geometry of Life" based on x-ray histotomography, population, genomic, and functional genomic analyses of complex traits in human and zebrafish; web-based science resources.
Craig Meyers
Distinguished Professor of Microbiology and Immunology
The differentiation-dependent life cycle of human papillomavirus (HPV) and HPV-associated oncogenesis.
Mark Shriver
Professor of Biological Anthropology
Human population genomics and complex disease mapping.
Costas Maranas
Donald B. Broughton Professor of Chemical Engineering
Computational studies of metabolism and gene regulation.
David Huff
Professor of Turfgrass Breeding and Genetics
Population genetics. Plant evolution and ecology. Crop improvement. Physiological tolerance to biotic and abiotic stress.
David Geiser
Professor of Mycology
Molecular evolutionary genetics of pathogenic and toxigenic fungi.
Robert Eckhardt
Professor
Genetic and environmental influences on growth and development in human populations.
Colin Barnstable
Professor and Chair of Neural Behavioral Sciences
How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.
Siela Maximova
Research Professor of Plant Biotechnology Co-Director, Endowed Program in the Molecular Biology of Cocoa
Molecular basis of plant-pathogen and plant-endophyte interactions. Biotechnology of tree crops. Development of sustainable energy crops.
Fumiko Kawasaki
Associate Research Professor
Genetic and Molecular Studies of Neural Function and Degeneration
Rongling Wu
Director of the Center for Statistical Genetics; Professor of Public Health Sciences
James Broach
Distinguished Professor and Chair of Biochemistry and Molecular Biology
Sinisa Dovat
Professor and Vice Chair for Basic Science Research, Department of Pediatrics; Professor of Biochemistry and Molecular Biology and of Pharmacology
Investigate the role of lymphoid master regulator, IKZF1/Ikaros, in the development of acute lymphoblastic leukemia (ALL); other transcriptional factors in leukemia; CK2 activity; chromatin remodeling; super-enhancers.
Idan Shalev
Assistant Professor of Biobehavioral Health
Interdisciplinary approach to identify mechanisms underpinning the biological embedding of stress across the lifespan with a special focus on biological aging.
Tim Miyashiro
Assistant Professor of Biochemistry and Molecular Biology
How bacteria adapt to a host environment. The mutualistic symbiosis established between the Hawaiian bobtail squid (Euprymna scolopes) and a bioluminescent bacterium (Vibrio fischeri).
Center for Infectious Disease Dynamics
Lynn Lin
Assistant Professor of Statistics
Bayesian mixture model development for classification, variable selection, design and model selection, structured and hierarchical non-parametric Bayesian methods, rare event detection, and statistical computation involving simulation and optimization.
Erin Connolly
Professor and Head of Plant Science
Molecular mechanisms of micronutrient transport. Iron uptake and compartmentalization. Metal ion homeostasis
Gang Ning
Director, Microscopy Core Facility
Using microscopy and flow cytometry to analyze structures and biochemical properties of cells.
Center for Infectious Disease Dynamics
Loida Escote-Carlson
Director, Master of Biotechnology Degree Program; Professor of Biochemistry and Molecular Biology
Suzanne Gonzalez
Assistant Professor of Psychiatry and Behavioral Health and of Pharmacology
My laboratory
focuses on neuropsychiatric genetics in diverse populations. I am particularly
interested in understanding how genetic polymorphisms within key physiological
pathways translate into clinical phenotypes of psychiatric disorders, such as
bipolar disease and schizophrenia.
Yasser El-Manzalawy
Assistant Research Professor of Information Sciences and Technology
Janine Kwapis
Assistant Professor of Biology
Molecular and epigenetic mechanisms underlying learning and memory and age-related memory impairments.
Yifei Huang
Assistant Professor of Biology
Developing novel bioinformatic methods and using them to address fundamental questions in evolutionary genomics and medical genomics.
Squire Booker
Evan Pugh Professor of Chemistry; Professor of Biochemistry and Molecular Biology
Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions. Most ongoing projects deal with members of the Radical S-adenosylmethionine Superfamily, a diverse group of enzymes that employ radical chemistry to catalyze transformations involved in post-transcriptional and post-translational modifications, cofactor biosynthesis, secondary metabolite biosynthesis, and enzyme activation.
Timothy Meredith
Assistant Professor of Biochemistry and Molecular Biology
Understanding how bacterial cell surface complex lipids are synthesized, to characterize structural modifications in response to varying growth environments, and to uncover how these changes are regulated.
Justin DiAngelo
Assistant Professor of Biochemistry and Molecular Biology
Emily Davenport
Assistant Professor of Biology
Understanding the complex relationship humans have with our microbiomes, using high-throughput sequencing technologies and novel computational and statistical techniques.
David Koslicki
Associate Professor of Computer Science and Engineering and Biology
Developing efficient algorithms to extract insight from high-throughput sequencing data.
Ruairidh Sawers
Assistant Professor of Plant Response to Abiotic Stress
Local adaptation and stress tolerance in crop plants and their wild relatives; plant nutrition; arbuscular mycorrhizae; maize genetics and genomics.
Sara Hermann
Assistant Professor of Arthropod Ecology and Trophic Interactions
Estelle Couradeau
Assistant Professor of Ecosystem Science & Management
Liana Burghardt
Huck Early Career Chair of Root Biology and Rhizosphere Interactions; Assistant Professor of Plant Science
Plant-microbe-climate interactions; the evolution and ecology of legumes and nitrogen-fixing rhizobia; the genomic basis and environment dependence of root, nodule, and mutualism traits; GWAS/transcriptomics/evolve & resequence methodologies
Zachary Szpiech
Assistant Professor of Biology
Population and evolutionary genetics, with applications to medical genetics, anthropology, and conservation
Tae Hyun Kim
Huck Early Career Chair; Assistant Professor of Avian Biology
Ganesh Srinivasan Anand
Associate Professor of Chemistry
Dynamics of large biomolecular complexes; uncovering what drives their assembly, regulation and function through mass spectrometry.
Center for Infectious Disease Dynamics
Lindsay Fernandez-Rhodes
Assistant Professor of Biobehavioral Health
The genetic epidemiology of complex diseases in diverse human populations and contexts.
Amie Boal
Associate Professor of Chemistry and of Biochemistry and Molecular Biology
The structural differences between members of large metalloenzyme superfamilies that share common features but promote different reactions or use distinct cofactors.